This term is obsolete.

GO:0045747 JSON

positive regulation of Notch signaling pathway

Biological Process

Definition (GO:0045747 GONUTS page)

Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.

8,348 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
positive regulation of N signalling pathway exact
stimulation of Notch signaling pathway narrow
up regulation of Notch signaling pathway exact
up-regulation of Notch signaling pathway exact
positive regulation of Notch signalling pathway exact
upregulation of Notch signaling pathway exact
positive regulation of N signaling pathway exact
activation of Notch signaling pathway narrow

Ancestor Chart

Ancestor chart for GO:0045747
Chart options
Ancestor chart

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0045747 positive regulation of Notch signaling pathway Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein B0BN23 10116 B0BN23_RAT GO:0008593 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O95858 9606 TSN15_HUMAN GO:0008593 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23091066
NOT-qualified manual protein Q5FVK6 10116 C2D1B_RAT GO:0008593 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q66HA5 10116 C2D1A_RAT GO:0008593 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q8BRN9 10090 C2D1B_MOUSE GO:0008593 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:26720614
NOT-qualified manual protein Q8K1A6 10090 C2D1A_MOUSE GO:0008593 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:26720614

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0035481 obsolete positive regulation of Notch signaling pathway involved in heart induction consider GO:0045747

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0045747 based on ALL annotations
The top 100 of 1,973 co-occurring terms
Co-occurring Term PR S% #Together #Compared
positive regulation of Notch signaling pathway
23,863.24 100.00 8,169 8,169
regulation of clathrin-dependent endocytosis
9,782.53 14.28 1,468 3,581
AP-2 adaptor complex binding
7,605.57 12.98 1,468 4,606
UDP-xylosyltransferase activity
4,503.64 9.92 1,413 7,487
negative regulation of stem cell differentiation
8,038.47 5.56 510 1,514
negative regulation of neuron differentiation
3,144.14 5.08 624 4,736
regulation of neurogenesis
3,202.10 4.92 588 4,382
neuronal stem cell population maintenance
4,882.98 4.25 416 2,033
Notch binding
1,451.77 4.21 981 16,125
inhibition of neuroepithelial cell differentiation
19,648.73 4.19 345 419
Totals 38907 281380
No co-occurrence statistics for GO:0045747 based on MANUAL annotations
The top 100 of 1,758 co-occurring terms
Co-occurring Term PR S% #Together #Compared
positive regulation of Notch signaling pathway
3,777.19 100.00 342 342
regulation of clathrin-dependent endocytosis
1,859.09 15.48 63 128
AP-2 adaptor complex binding
1,844.67 15.44 63 129
heart induction
1,555.31 5.65 21 51
pulmonary valve morphogenesis
1,149.58 5.38 21 69
aortic valve morphogenesis
712.09 5.22 23 122
UDP-xylosyltransferase activity
351.63 4.81 31 333
phosphatase regulator activity
1,735.47 4.70 17 37
Notch binding
236.07 4.25 40 640
ventricular septum morphogenesis
466.02 3.98 19 154
Totals 1566 12167

Change Log

Timestamp Action Category Detail
2019-09-29 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2011-01-16 Added RELATION is a GO:0009967 (positive regulation of signal transduction)
2011-01-16 Deleted RELATION is a GO:0035468 (positive regulation of signaling pathway)
2010-04-21 Added RELATION is a GO:0035468 (positive regulation of signaling pathway)
2010-04-21 Deleted RELATION is a GO:0009967 (positive regulation of signal transduction)
2008-05-13 Added DEFINITION Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
2008-05-12 Deleted DEFINITION Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
2008-04-01 Updated RELATION is a GO:0008593 (regulation of Notch signaling pathway)
2008-04-01 Added RELATION positively regulates GO:0007219 (Notch signaling pathway)
2008-04-01 Updated RELATION is a GO:0009967 (positive regulation of signal transduction)
Timestamp Action Category Detail
2004-02-14 Updated TERM positive regulation of Notch signaling pathway
2003-08-07 Updated TERM positive regulation of N signaling pathway
2002-08-20 Added TERM positive regulation of N receptor signaling pathway
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
2008-05-12 Deleted DEFINITION Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
2007-09-10 Added SYNONYM positive regulation of Notch signalling pathway
2007-09-10 Deleted SYNONYM positive regulation of Notch signaling pathway
2007-08-09 Added SYNONYM upregulation of Notch signaling pathway
2007-08-09 Deleted SYNONYM positive regulation of N signaling pathway
2007-08-09 Deleted SYNONYM positive regulation of Notch signaling pathway
2007-08-09 Added SYNONYM up-regulation of Notch signaling pathway
2007-08-09 Added SYNONYM up regulation of Notch signaling pathway
2007-08-09 Added SYNONYM stimulation of Notch signaling pathway
2007-08-09 Added SYNONYM positive regulation of Notch signaling pathway
2007-08-09 Added SYNONYM positive regulation of N signalling pathway
2007-08-09 Added SYNONYM positive regulation of N signaling pathway
2007-08-09 Added SYNONYM activation of Notch signaling pathway
2007-08-09 Deleted SYNONYM upregulation of Notch signaling pathway
2007-08-09 Deleted SYNONYM up-regulation of Notch signaling pathway
2007-08-09 Deleted SYNONYM up regulation of Notch signaling pathway
2007-08-09 Deleted SYNONYM stimulation of Notch signaling pathway
2007-08-09 Deleted SYNONYM activation of Notch signaling pathway
2007-08-09 Deleted SYNONYM positive regulation of N signalling pathway
2007-02-23 Added SYNONYM activation of Notch signaling pathway
2007-02-23 Added SYNONYM up-regulation of Notch signaling pathway
2007-02-23 Added SYNONYM upregulation of Notch signaling pathway
2007-02-23 Added SYNONYM up regulation of Notch signaling pathway
2007-02-23 Added SYNONYM stimulation of Notch signaling pathway
2006-05-04 Updated DEFINITION Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
2005-10-21 Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the Notch signaling pathway.
2004-04-19 Added SYNONYM positive regulation of Notch signaling pathway
2004-04-19 Added SYNONYM positive regulation of N signaling pathway
2004-04-19 Added SYNONYM positive regulation of N signalling pathway
2004-04-16 Deleted SYNONYM positive regulation of Notch signaling pathway
2004-04-16 Deleted SYNONYM positive regulation of N signaling pathway
2004-04-16 Deleted SYNONYM positive regulation of N signalling pathway
2004-02-14 Added SYNONYM positive regulation of N signaling pathway
2003-11-13 Added SYNONYM positive regulation of N signalling pathway
2003-08-07 Added SYNONYM positive regulation of Notch signaling pathway
2003-08-07 Updated DEFINITION Any process that activates or increases the rate of the Notch signaling pathway.
2002-11-27 Added DEFINITION Any process that activates or increases the rate of N receptor signaling pathway activity.
Timestamp Action Category Detail
2011-01-16 Added RELATION is a GO:0009967 (positive regulation of signal transduction)
2011-01-16 Deleted RELATION is a GO:0035468 (positive regulation of signaling pathway)
2010-04-21 Added RELATION is a GO:0035468 (positive regulation of signaling pathway)
2010-04-21 Deleted RELATION is a GO:0009967 (positive regulation of signal transduction)
2008-04-01 Updated RELATION is a GO:0008593 (regulation of Notch signaling pathway)
2008-04-01 Added RELATION positively regulates GO:0007219 (Notch signaling pathway)
2008-04-01 Updated RELATION is a GO:0009967 (positive regulation of signal transduction)
Timestamp Action Category Detail
Timestamp Action Category Detail
2019-09-29 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
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