This term is obsolete.

GO:0045776 JSON

negative regulation of blood pressure

Biological Process

Definition (GO:0045776 GONUTS page)

Any process in which the force of blood traveling through the circulatory system is decreased.

6,927 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
down-regulation of blood pressure exact
downregulation of blood pressure exact
inhibition of blood pressure narrow
down regulation of blood pressure exact

Ancestor Chart

Ancestor chart for GO:0045776
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045776

Child Term Relationship to
GO:0045776
negative regulation of systemic arterial blood pressure
is_a
negative regulation of blood pressure in another organism
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0045776 negative regulation of blood pressure Never in Taxon 2 Bacteria
GO:0045776 negative regulation of blood pressure Never in Taxon 2157 Archaea
GO:0045776 negative regulation of blood pressure Never in Taxon 4896 Schizosaccharomyces pombe
GO:0045776 negative regulation of blood pressure Never in Taxon 4932 Saccharomyces cerevisiae

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P18293 10090 ANPRA_MOUSE GO:0008217 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11997476
NOT-qualified manual protein P18910 10116 ANPRA_RAT GO:0008217 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P26684 10116 EDNRA_RAT GO:0008217 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q61614 10090 EDNRA_MOUSE GO:0008217 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:15928212
NOT-qualified manual protein Q99JA0-1 10090 CALCA_MOUSE GO:0008217 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10532808
NOT-qualified manual protein Q9ERZ8 10116 TRPV4_RAT GO:0008217 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23136043

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0045776 based on ALL annotations
The top 100 of 1,287 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of blood pressure
199,732.36 100.00 976 976
response to cocaine
53,966.68 12.93 194 718
positive regulation of renal albumin absorption
197,932.97 11.26 110 111
negative regulation of intracellular protein transport
175,764.47 11.10 110 125
positive regulation of myeloid cell apoptotic process
135,620.73 10.70 110 162
nervous system process involved in regulation of systemic arterial blood pressure
121,014.31 9.88 103 170
negative regulation of dopamine receptor signaling pathway
107,148.09 9.67 103 192
positive regulation of renal sodium excretion
103,451.13 9.44 101 195
positive regulation of glial cell-derived neurotrophic factor production
102,923.31 9.43 101 196
positive regulation of dopamine uptake involved in synaptic transmission
100,864.84 9.40 101 200
Totals 10867 80291
No co-occurrence statistics for GO:0045776 based on MANUAL annotations
The top 100 of 1,173 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of blood pressure
8,970.83 100.00 144 144
nitric-oxide synthase activity
5,419.87 31.87 58 96
arginine catabolic process
5,364.00 31.69 58 97
nitric oxide mediated signal transduction
5,203.08 31.18 58 100
nitric oxide biosynthetic process
1,905.89 16.16 58 273
positive regulation of metanephric podocyte development
8,970.83 11.11 16 16
positive regulation of renal albumin absorption
8,970.83 11.11 16 16
negative regulation of metanephric mesenchymal cell migration
8,970.83 11.11 16 16
negative regulation of intracellular protein transport
7,974.07 10.96 16 18
detection of oxidative stress
7,974.07 10.96 16 18
Totals 1545 11432

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:2157 (Archaea)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:2 (Bacteria)
2010-12-12 Deleted DEFINITION Any process by which the force of blood traveling through the circulatory system is decreased.
2010-12-12 Added DEFINITION Any process in which the force of blood traveling through the circulatory system is decreased.
2009-10-31 Deleted RELATION is a GO:0065008 (regulation of biological quality)
2009-10-30 Deleted RELATION part of GO:0008217 (regulation of blood pressure)
2009-10-30 Added RELATION is a GO:0008217 (regulation of blood pressure)
2009-10-30 Deleted DEFINITION The process by which the force of blood traveling through the circulatory system is decreased.
Timestamp Action Category Detail
2002-08-20 Added TERM negative regulation of blood pressure
Timestamp Action Category Detail
2010-12-12 Deleted DEFINITION Any process by which the force of blood traveling through the circulatory system is decreased.
2010-12-12 Added DEFINITION Any process in which the force of blood traveling through the circulatory system is decreased.
2009-10-30 Deleted DEFINITION The process by which the force of blood traveling through the circulatory system is decreased.
2009-10-30 Added DEFINITION Any process by which the force of blood traveling through the circulatory system is decreased.
2008-05-13 Added DEFINITION The process by which the force of blood traveling through the circulatory system is decreased.
2008-05-12 Deleted DEFINITION The process by which the force of blood traveling through the circulatory system is decreased.
2007-11-27 Updated DEFINITION The process by which the force of blood traveling through the circulatory system is decreased.
2007-08-09 Added SYNONYM down-regulation of blood pressure
2007-08-09 Added SYNONYM down regulation of blood pressure
2007-08-09 Added SYNONYM downregulation of blood pressure
2007-08-09 Deleted SYNONYM downregulation of blood pressure
2007-08-09 Deleted SYNONYM inhibition of blood pressure
2007-08-09 Deleted SYNONYM down regulation of blood pressure
2007-08-09 Deleted SYNONYM down-regulation of blood pressure
2007-08-09 Added SYNONYM inhibition of blood pressure
2007-02-23 Added SYNONYM downregulation of blood pressure
2007-02-23 Added SYNONYM down-regulation of blood pressure
2007-02-23 Added SYNONYM inhibition of blood pressure
2007-02-23 Added SYNONYM down regulation of blood pressure
2002-11-27 Added DEFINITION Any process that reduces blood pressure.
Timestamp Action Category Detail
2009-10-31 Deleted RELATION is a GO:0065008 (regulation of biological quality)
2009-10-30 Deleted RELATION part of GO:0008217 (regulation of blood pressure)
2009-10-30 Added RELATION is a GO:0008217 (regulation of blood pressure)
2008-04-01 Updated RELATION part of GO:0008217 (regulation of blood pressure)
2008-04-01 Updated RELATION is a GO:0065008 (regulation of biological quality)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:2157 (Archaea)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:2 (Bacteria)
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