GO:0045776
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negative regulation of blood pressure
Biological Process
Definition (GO:0045776 GONUTS page)
Any process in which the force of blood traveling through the circulatory system is decreased.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
down-regulation of blood pressure | exact |
downregulation of blood pressure | exact |
inhibition of blood pressure | narrow |
down regulation of blood pressure | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0045776
Child Term | Relationship to GO:0045776 |
---|---|
negative regulation of systemic arterial blood pressure
|
is_a |
negative regulation of blood pressure in another organism
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0045776 | negative regulation of blood pressure | Never in Taxon | 2 | Bacteria | |
GO:0045776 | negative regulation of blood pressure | Never in Taxon | 2157 | Archaea | |
GO:0045776 | negative regulation of blood pressure | Never in Taxon | 4896 | Schizosaccharomyces pombe | |
GO:0045776 | negative regulation of blood pressure | Never in Taxon | 4932 | Saccharomyces cerevisiae |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P18293 | 10090 | ANPRA_MOUSE | GO:0008217 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11997476 | |
NOT-qualified manual | protein | P18910 | 10116 | ANPRA_RAT | GO:0008217 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P26684 | 10116 | EDNRA_RAT | GO:0008217 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q61614 | 10090 | EDNRA_MOUSE | GO:0008217 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:15928212 | |
NOT-qualified manual | protein | Q99JA0-1 | 10090 | CALCA_MOUSE | GO:0008217 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10532808 | |
NOT-qualified manual | protein | Q9ERZ8 | 10116 | TRPV4_RAT | GO:0008217 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:23136043 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0045776 based on ALL annotations
The top 100 of 1,287 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of blood pressure
|
199,732.36 | 100.00 | 976 | 976 |
response to cocaine
|
53,966.68 | 12.93 | 194 | 718 |
positive regulation of renal albumin absorption
|
197,932.97 | 11.26 | 110 | 111 |
negative regulation of intracellular protein transport
|
175,764.47 | 11.10 | 110 | 125 |
positive regulation of myeloid cell apoptotic process
|
135,620.73 | 10.70 | 110 | 162 |
nervous system process involved in regulation of systemic arterial blood pressure
|
121,014.31 | 9.88 | 103 | 170 |
negative regulation of dopamine receptor signaling pathway
|
107,148.09 | 9.67 | 103 | 192 |
positive regulation of renal sodium excretion
|
103,451.13 | 9.44 | 101 | 195 |
positive regulation of glial cell-derived neurotrophic factor production
|
102,923.31 | 9.43 | 101 | 196 |
positive regulation of dopamine uptake involved in synaptic transmission
|
100,864.84 | 9.40 | 101 | 200 |
Totals | 10867 | 80291 |
No co-occurrence statistics for GO:0045776 based on MANUAL annotations
The top 100 of 1,173 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of blood pressure
|
8,970.83 | 100.00 | 144 | 144 |
nitric-oxide synthase activity
|
5,419.87 | 31.87 | 58 | 96 |
arginine catabolic process
|
5,364.00 | 31.69 | 58 | 97 |
nitric oxide mediated signal transduction
|
5,203.08 | 31.18 | 58 | 100 |
nitric oxide biosynthetic process
|
1,905.89 | 16.16 | 58 | 273 |
positive regulation of metanephric podocyte development
|
8,970.83 | 11.11 | 16 | 16 |
positive regulation of renal albumin absorption
|
8,970.83 | 11.11 | 16 | 16 |
negative regulation of metanephric mesenchymal cell migration
|
8,970.83 | 11.11 | 16 | 16 |
negative regulation of intracellular protein transport
|
7,974.07 | 10.96 | 16 | 18 |
detection of oxidative stress
|
7,974.07 | 10.96 | 16 | 18 |
Totals | 1545 | 11432 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2010-12-12 | Deleted | DEFINITION | Any process by which the force of blood traveling through the circulatory system is decreased. |
2010-12-12 | Added | DEFINITION | Any process in which the force of blood traveling through the circulatory system is decreased. |
2009-10-31 | Deleted | RELATION | is a GO:0065008 (regulation of biological quality) |
2009-10-30 | Deleted | RELATION | part of GO:0008217 (regulation of blood pressure) |
2009-10-30 | Added | RELATION | is a GO:0008217 (regulation of blood pressure) |
2009-10-30 | Deleted | DEFINITION | The process by which the force of blood traveling through the circulatory system is decreased. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-08-20 | Added | TERM | negative regulation of blood pressure |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-12-12 | Deleted | DEFINITION | Any process by which the force of blood traveling through the circulatory system is decreased. |
2010-12-12 | Added | DEFINITION | Any process in which the force of blood traveling through the circulatory system is decreased. |
2009-10-30 | Deleted | DEFINITION | The process by which the force of blood traveling through the circulatory system is decreased. |
2009-10-30 | Added | DEFINITION | Any process by which the force of blood traveling through the circulatory system is decreased. |
2008-05-13 | Added | DEFINITION | The process by which the force of blood traveling through the circulatory system is decreased. |
2008-05-12 | Deleted | DEFINITION | The process by which the force of blood traveling through the circulatory system is decreased. |
2007-11-27 | Updated | DEFINITION | The process by which the force of blood traveling through the circulatory system is decreased. |
2007-08-09 | Added | SYNONYM | down-regulation of blood pressure |
2007-08-09 | Added | SYNONYM | down regulation of blood pressure |
2007-08-09 | Added | SYNONYM | downregulation of blood pressure |
2007-08-09 | Deleted | SYNONYM | downregulation of blood pressure |
2007-08-09 | Deleted | SYNONYM | inhibition of blood pressure |
2007-08-09 | Deleted | SYNONYM | down regulation of blood pressure |
2007-08-09 | Deleted | SYNONYM | down-regulation of blood pressure |
2007-08-09 | Added | SYNONYM | inhibition of blood pressure |
2007-02-23 | Added | SYNONYM | downregulation of blood pressure |
2007-02-23 | Added | SYNONYM | down-regulation of blood pressure |
2007-02-23 | Added | SYNONYM | inhibition of blood pressure |
2007-02-23 | Added | SYNONYM | down regulation of blood pressure |
2002-11-27 | Added | DEFINITION | Any process that reduces blood pressure. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-10-31 | Deleted | RELATION | is a GO:0065008 (regulation of biological quality) |
2009-10-30 | Deleted | RELATION | part of GO:0008217 (regulation of blood pressure) |
2009-10-30 | Added | RELATION | is a GO:0008217 (regulation of blood pressure) |
2008-04-01 | Updated | RELATION | part of GO:0008217 (regulation of blood pressure) |
2008-04-01 | Updated | RELATION | is a GO:0065008 (regulation of biological quality) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
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