GO:0045900
JSON
negative regulation of translational elongation
Biological Process
Definition (GO:0045900 GONUTS page)
Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
inhibition of translational elongation | narrow |
down-regulation of translational elongation | exact |
down regulation of translational elongation | exact |
downregulation of translational elongation | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0045900
Child Term | Relationship to GO:0045900 |
---|---|
negative regulation of cytoplasmic translational elongation
|
is_a |
negative regulation of mitochondrial translational elongation
|
is_a |
negative regulation of selenocysteine incorporation
|
is_a |
negative regulation of translational frameshifting
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5Y7T8 | 10116 | A0A8I5Y7T8_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5YBE4 | 10116 | A0A8I5YBE4_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN4 | 10116 | A6HXN4_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN5 | 10116 | A6HXN5_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN7 | 10116 | A6HXN7_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JXC6 | 10116 | A6JXC6_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZJ50 | 10116 | D3ZJ50_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D4A417 | 10116 | D4A417_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P9WNV7 | 83332 | DNAJ2_MYCTU | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487 | |
NOT-qualified manual | protein | Q15170 | 9606 | TCAL1_HUMAN | GO:0010629 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:7971997 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR008832 | Signal recognition particle SRP9 |
InterPro | IPR022374 | Energy-dependent translational throttle protein EttA |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0045900 based on ALL annotations
The top 100 of 137 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of translational elongation
|
3,268.76 | 100.00 | 59,637 | 59,637 |
ribosomal small subunit binding
|
882.23 | 21.99 | 32,380 | 119,972 |
regulation of translation
|
479.11 | 14.51 | 55,658 | 379,733 |
cytosolic small ribosomal subunit
|
238.19 | 6.87 | 32,373 | 444,264 |
ribosome binding
|
143.87 | 4.09 | 21,735 | 493,807 |
tRNA binding
|
61.06 | 1.82 | 24,135 | 1,291,960 |
signal recognition particle, endoplasmic reticulum targeting
|
83.50 | 1.29 | 1,517 | 59,385 |
signal recognition particle
|
76.78 | 1.24 | 1,517 | 64,587 |
7S RNA binding
|
69.75 | 1.17 | 1,517 | 71,093 |
rRNA binding
|
38.74 | 1.16 | 24,137 | 2,036,482 |
Totals | 400535 | 138829813 |
No co-occurrence statistics for GO:0045900 based on MANUAL annotations
The top 53 of 53 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of translational elongation
|
12,790.09 | 100.00 | 101 | 101 |
ribosomal small subunit binding
|
1,748.42 | 13.49 | 92 | 673 |
regulation of translation at synapse, modulating synaptic transmission
|
8,526.73 | 7.62 | 8 | 12 |
negative regulation of cytoplasmic translation
|
627.73 | 3.13 | 8 | 163 |
mRNA regulatory element binding translation repressor activity
|
511.60 | 2.73 | 8 | 200 |
translation factor activity, RNA binding
|
520.53 | 2.63 | 7 | 172 |
poly-pyrimidine tract binding
|
386.12 | 2.23 | 8 | 265 |
dormancy process
|
2,131.68 | 1.80 | 2 | 12 |
cytosolic small ribosomal subunit
|
203.56 | 1.59 | 90 | 5,655 |
GTPase inhibitor activity
|
609.05 | 1.42 | 2 | 42 |
Totals | 456 | 863145 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. |
2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of translational elongation. |
2008-05-13 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of translational elongation. |
2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of translational elongation. |
2008-04-01 | Updated | RELATION | is a GO:0017148 (negative regulation of translation) |
2008-04-01 | Updated | RELATION | is a GO:0006448 (regulation of translational elongation) |
2008-04-01 | Added | RELATION | negatively regulates GO:0006414 (translational elongation) |
2007-08-09 | Deleted | SYNONYM | down regulation of translational elongation |
2007-08-09 | Added | SYNONYM | downregulation of translational elongation |
2007-08-09 | Added | SYNONYM | down-regulation of translational elongation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-08-20 | Added | TERM | negative regulation of translational elongation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. |
2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of translational elongation. |
2008-05-13 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of translational elongation. |
2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of translational elongation. |
2007-08-09 | Deleted | SYNONYM | down regulation of translational elongation |
2007-08-09 | Added | SYNONYM | downregulation of translational elongation |
2007-08-09 | Added | SYNONYM | down-regulation of translational elongation |
2007-08-09 | Deleted | SYNONYM | inhibition of translational elongation |
2007-08-09 | Deleted | SYNONYM | downregulation of translational elongation |
2007-08-09 | Deleted | SYNONYM | down-regulation of translational elongation |
2007-08-09 | Added | SYNONYM | down regulation of translational elongation |
2007-08-09 | Added | SYNONYM | inhibition of translational elongation |
2007-02-23 | Added | SYNONYM | downregulation of translational elongation |
2007-02-23 | Added | SYNONYM | inhibition of translational elongation |
2007-02-23 | Added | SYNONYM | down-regulation of translational elongation |
2007-02-23 | Added | SYNONYM | down regulation of translational elongation |
2006-05-04 | Updated | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of translational elongation. |
2005-10-21 | Updated | DEFINITION | Any process that stops, prevents or reduces the rate, frequency or extent of translational elongation. |
2002-11-27 | Added | DEFINITION | Any process that stops, prevents or reduces the rate of translational elongation. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0017148 (negative regulation of translation) |
2008-04-01 | Updated | RELATION | is a GO:0006448 (regulation of translational elongation) |
2008-04-01 | Added | RELATION | negatively regulates GO:0006414 (translational elongation) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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