This term is obsolete.
See also the molecular function term 'ferrochelatase activity ; GO:0004325'.

GO:0046501 JSON

protoporphyrinogen IX metabolic process

Biological Process

Definition (GO:0046501 GONUTS page)

The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.

Comments

See also the molecular function term 'ferrochelatase activity ; GO:0004325'.

286,775 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
protoporphyrinogen IX metabolism exact

Ancestor Chart

Ancestor chart for GO:0046501
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046501

Child Term Relationship to
GO:0046501
protoporphyrinogen IX biosynthetic process
is_a

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input_or_output CHEBI CHEBI:57307 protoporphyrinogen(2-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0046501 based on ALL annotations
The top 95 of 95 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protoporphyrinogen IX metabolic process
1,031,422.20 100.00 189 189
regulation of hemoglobin biosynthetic process
1,009,359.56 94.82 183 187
negative regulation of hemoglobin biosynthetic process
1,020,211.06 47.89 91 92
detection of UV
839,741.90 43.81 92 113
integrated stress response signaling
178,859.33 14.56 90 519
HRI-mediated signaling
142,592.92 12.00 90 651
acute inflammatory response
137,021.05 11.62 91 685
very-low-density lipoprotein particle assembly
127,885.23 10.97 92 742
response to iron ion starvation
121,185.37 10.40 90 766
multicellular organismal-level iron ion homeostasis
83,040.15 8.03 183 2,273
Totals 4865 138129012
No co-occurrence statistics for GO:0046501 based on MANUAL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protoporphyrinogen IX metabolic process
117,436.27 100.00 11 11
regulation of hemoglobin biosynthetic process
102,756.73 58.33 7 8
detection of UV
53,380.13 29.41 5 11
response to platinum ion
52,193.90 25.00 4 9
heme B biosynthetic process
32,882.16 24.14 7 25
heme O biosynthetic process
24,178.06 18.42 7 34
negative regulation of hemoglobin biosynthetic process
58,718.14 15.38 2 4
very-low-density lipoprotein particle assembly
17,270.04 12.50 5 34
response to methylmercury
10,924.31 8.00 4 43
heme metabolic process
10,676.02 7.84 4 44
Totals 237 600417

Change Log

Timestamp Action Category Detail
2013-06-13 Deleted RELATION is a GO:0043170 (macromolecule metabolic process)
2013-02-02 Added RELATION is a GO:0043170 (macromolecule metabolic process)
2012-10-29 Deleted RELATION is a GO:0006725 (obsolete cellular aromatic compound metabolic process)
2009-07-06 Added RELATION is a GO:0006725 (obsolete cellular aromatic compound metabolic process)
2008-05-13 Added DEFINITION The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
2008-04-01 Updated RELATION is a GO:0006778 (porphyrin-containing compound metabolic process)
2007-08-09 Added SYNONYM protoporphyrinogen IX metabolism
2007-08-09 Deleted SYNONYM protoporphyrinogen IX metabolism
2007-01-29 Added SYNONYM protoporphyrinogen IX metabolism
Timestamp Action Category Detail
2007-01-15 Updated TERM protoporphyrinogen IX metabolic process
2002-10-02 Added TERM protoporphyrinogen IX metabolism
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
2007-08-09 Added SYNONYM protoporphyrinogen IX metabolism
2007-08-09 Deleted SYNONYM protoporphyrinogen IX metabolism
2007-01-29 Added SYNONYM protoporphyrinogen IX metabolism
2006-05-04 Updated DEFINITION The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
2005-01-21 Updated DEFINITION The chemical reactions involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
2004-07-22 Updated DEFINITION The chemical reactions and physical changes involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
2002-11-27 Added DEFINITION The chemical reactions and physical changes involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase (GO:0004325), which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
Timestamp Action Category Detail
2013-06-13 Deleted RELATION is a GO:0043170 (macromolecule metabolic process)
2013-02-02 Added RELATION is a GO:0043170 (macromolecule metabolic process)
2012-10-29 Deleted RELATION is a GO:0006725 (obsolete cellular aromatic compound metabolic process)
2009-07-06 Added RELATION is a GO:0006725 (obsolete cellular aromatic compound metabolic process)
2008-04-01 Updated RELATION is a GO:0006778 (porphyrin-containing compound metabolic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
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