This term is obsolete.

GO:0046621 JSON

negative regulation of organ growth

Biological Process

Definition (GO:0046621 GONUTS page)

Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.

7,593 annotations

Ancestor Chart

Ancestor chart for GO:0046621
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046621

Child Term Relationship to
GO:0046621
GO:0061914
negative regulation of growth plate cartilage chondrocyte proliferation
is_a
GO:0061117
negative regulation of heart growth
is_a

Cross-references

Database ID Description
InterPro IPR033276 E3 ubiquitin-protein ligase BIG BROTHER
InterPro IPR037547 Protein SAMBA

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0046621 based on ALL annotations
The top 100 of 926 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0046621
negative regulation of organ growth
29,991.66 100.00 6,607 6,607
GO:0035330
regulation of hippo signaling
26,887.58 53.16 3,742 4,174
GO:0019900
kinase binding
3,531.94 10.83 3,784 32,132
GO:0048437
floral organ development
24,918.99 9.98 673 810
GO:0060090
molecular adaptor activity
1,318.49 4.26 3,766 85,665
GO:0031624
ubiquitin conjugating enzyme binding
1,383.71 3.98 1,479 32,057
GO:0035265
organ growth
4,193.11 3.62 308 2,203
GO:0060800
regulation of cell differentiation involved in embryonic placenta development
19,823.25 2.88 193 292
GO:0003157
endocardium development
10,839.68 2.78 193 534
GO:1902043
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
6,312.31 2.63 193 917
Totals 37175 1929226
No co-occurrence statistics for GO:0046621 based on MANUAL annotations
The top 100 of 788 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0046621
negative regulation of organ growth
10,228.50 100.00 138 138
GO:0035330
regulation of hippo signaling
5,941.55 40.51 79 136
GO:0019900
kinase binding
1,439.69 12.97 86 611
GO:0035265
organ growth
1,847.73 10.57 28 155
GO:0035332
positive regulation of hippo signaling
1,124.01 6.67 20 182
GO:0060800
regulation of cell differentiation involved in embryonic placenta development
8,182.80 5.71 8 10
GO:0048625
myoblast fate commitment
5,844.86 5.56 8 14
GO:0032252
secretory granule localization
4,091.40 5.33 8 20
GO:0048641
regulation of skeletal muscle tissue development
3,896.57 5.30 8 21
GO:1901142
insulin metabolic process
3,557.74 5.23 8 23
Totals 1164 21672

Change Log

Timestamp Action Category Detail
2015-06-25 Deleted RELATION is a GO:0045926 (negative regulation of growth)
2014-11-22 Added RELATION is a GO:0048640 (negative regulation of developmental growth)
2012-12-21 Added RELATION is a GO:0051241 (negative regulation of multicellular organismal process)
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of growth of an organ of an organism.
2009-09-04 Deleted SYNONYM negative regulation of organ size
2009-09-04 Deleted SYNONYM inhibition of organ size
2009-09-04 Deleted SYNONYM down regulation of organ size
2009-09-04 Deleted SYNONYM downregulation of organ size
2009-09-04 Deleted SYNONYM down-regulation of organ size
Timestamp Action Category Detail
2007-10-13 Updated TERM negative regulation of organ growth
2002-10-29 Added TERM negative regulation of organ size
Timestamp Action Category Detail
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of growth of an organ of an organism.
2009-09-04 Deleted SYNONYM negative regulation of organ size
2009-09-04 Deleted SYNONYM inhibition of organ size
2009-09-04 Deleted SYNONYM down regulation of organ size
2009-09-04 Deleted SYNONYM downregulation of organ size
2009-09-04 Deleted SYNONYM down-regulation of organ size
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of growth of an organ of an organism.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of growth of an organ of an organism.
2007-10-13 Added SYNONYM negative regulation of organ size
2007-08-09 Added SYNONYM inhibition of organ size
2007-08-09 Added SYNONYM down-regulation of organ size
2007-08-09 Added SYNONYM downregulation of organ size
2007-08-09 Added SYNONYM down regulation of organ size
2007-08-09 Deleted SYNONYM inhibition of organ size
2007-08-09 Deleted SYNONYM downregulation of organ size
2007-08-09 Deleted SYNONYM down-regulation of organ size
2007-08-09 Deleted SYNONYM down regulation of organ size
2007-02-23 Added SYNONYM downregulation of organ size
2007-02-23 Added SYNONYM down regulation of organ size
2007-02-23 Added SYNONYM down-regulation of organ size
2007-02-23 Added SYNONYM inhibition of organ size
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of growth of an organ of an organism.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of growth of an organ of an organism.
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of growth of an organ of an organism.
Timestamp Action Category Detail
2015-06-25 Deleted RELATION is a GO:0045926 (negative regulation of growth)
2014-11-22 Added RELATION is a GO:0048640 (negative regulation of developmental growth)
2012-12-21 Added RELATION is a GO:0051241 (negative regulation of multicellular organismal process)
2008-04-01 Updated RELATION is a GO:0045926 (negative regulation of growth)
2008-04-01 Updated RELATION is a GO:0046620 (regulation of organ growth)
2008-04-01 Added RELATION negatively regulates GO:0035265 (organ growth)
Timestamp Action Category Detail
Timestamp Action Category Detail
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