Note that this should not be confused with 'geranylgeranyl-diphosphate geranylgeranyltransferase activity ; GO:0016767', EC:2.5.1.32. This activity is the second part of the formation of phytoene from geranylgeranyl-diphosphate, the first stage of which is catalyzed by EC:2.5.1.32.
GO:0046905
JSON
15-cis-phytoene synthase activity
Molecular Function
Definition (GO:0046905 GONUTS page)
Catalysis of the reaction: 2 geranylgeranyl diphosphate -> 15-cis-phytoene + 2 diphosphate. PMID:12641468
Comments
Note that this should not be confused with 'geranylgeranyl-diphosphate geranylgeranyltransferase activity ; GO:0016767', EC:2.5.1.32. This activity is the second part of the formation of phytoene from geranylgeranyl-diphosphate, the first stage of which is catalyzed by EC:2.5.1.32.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
phytoene synthase activity | broad |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0046905 | 15-cis-phytoene synthase activity | Only in Taxon | 33090 | Viridiplantae |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | E9PTA2 | 10116 | TRPM2_RAT | GO:0016787 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | O94759 | 9606 | TRPM2_HUMAN | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | P95028 | 83331 | P95028_MYCTO | GO:0008610 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16952959 | |
NOT-qualified manual | protein | Q2M2R8 | 10116 | PEX5_RAT | GO:0008299 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q62226 | 10090 | SHH_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113 | |
NOT-qualified manual | protein | Q63673 | 10116 | SHH_RAT | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
RHEA | 34479 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:58011 | (1R,2R,3R)-prephytoene diphosphate(3-) |
has_participant | CHEBI | CHEBI:27787 | 15-cis-phytoene |
has_participant | CHEBI | CHEBI:33019 | diphosphate(3-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0046905 based on ALL annotations
The top 45 of 45 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
15-cis-phytoene synthase activity
|
443,042.70 | 100.00 | 440 | 440 |
plastoglobule
|
131,036.54 | 29.44 | 433 | 1,464 |
carotene biosynthetic process
|
76,663.68 | 17.30 | 439 | 2,537 |
geranylgeranyl-diphosphate geranylgeranyltransferase activity
|
23,061.49 | 5.21 | 440 | 8,453 |
farnesyltranstransferase activity
|
6,573.97 | 1.48 | 432 | 29,114 |
squalene synthase [NAD(P)H] activity
|
5,764.32 | 1.30 | 434 | 33,357 |
carotenoid biosynthetic process
|
3,174.12 | 0.72 | 440 | 61,415 |
lycopene beta cyclase activity
|
318.90 | 0.07 | 7 | 9,725 |
intramolecular lyase activity
|
133.40 | 0.03 | 7 | 23,248 |
biosynthetic process
|
126.44 | 0.03 | 435 | 1,524,289 |
Totals | 4143 | 165023167 |
No co-occurrence statistics for GO:0046905 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
15-cis-phytoene synthase activity
|
49,684.58 | 100.00 | 26 | 26 |
geranylgeranyl-diphosphate geranylgeranyltransferase activity
|
7,527.97 | 15.06 | 25 | 165 |
carotenoid biosynthetic process
|
3,667.99 | 7.28 | 22 | 298 |
plastoglobule
|
4,731.86 | 7.23 | 6 | 63 |
lycopene beta cyclase activity
|
4,731.86 | 7.23 | 6 | 63 |
carotene biosynthetic process
|
1,667.27 | 2.94 | 5 | 149 |
chloroplast
|
5.61 | 0.01 | 1 | 8,862 |
membrane
|
0.81 | 0.00 | 1 | 61,077 |
Totals | 92 | 70703 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-04-04 | Added | CONSTRAINT | in_taxon NCBITaxon:33090 (Viridiplantae) |
2021-03-28 | Added | RELATION | is a GO:0016462 (pyrophosphatase activity) |
2021-03-28 | Deleted | RELATION | is a GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups) |
2021-03-28 | Added | XREF | RHEA:34479 |
2021-03-28 | Added | SYNONYM | phytoene synthase activity |
2021-03-28 | Updated | TERM | 15-cis-phytoene synthase activity |
2021-03-28 | Added | DEFINITION | Catalysis of the reaction: 2 geranylgeranyl diphosphate -> 15-cis-phytoene + 2 diphosphate. |
2021-03-28 | Deleted | DEFINITION | Catalysis of the reaction: prephytoene pyrophosphate = phytoene + diphosphate. |
2018-07-18 | Added | RELATION | is a GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups) |
2018-07-18 | Deleted | RELATION | is a GO:0003824 (catalytic activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-28 | Updated | TERM | 15-cis-phytoene synthase activity |
2003-04-05 | Added | TERM | phytoene synthase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-28 | Added | SYNONYM | phytoene synthase activity |
2021-03-28 | Added | DEFINITION | Catalysis of the reaction: 2 geranylgeranyl diphosphate -> 15-cis-phytoene + 2 diphosphate. |
2021-03-28 | Deleted | DEFINITION | Catalysis of the reaction: prephytoene pyrophosphate = phytoene + diphosphate. |
2010-10-08 | Added | DEFINITION | Catalysis of the reaction: prephytoene pyrophosphate = phytoene + diphosphate. |
2010-10-08 | Deleted | DEFINITION | Catalysis of the reaction: prephytoene pyrophosphate = phytoene + pyrophosphate. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: prephytoene pyrophosphate = phytoene + pyrophosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: prephytoene pyrophosphate = phytoene + pyrophosphate. |
2003-04-05 | Added | DEFINITION | Catalysis of the reaction: prephytoene pyrophosphate = phytoene + pyrophosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-28 | Added | RELATION | is a GO:0016462 (pyrophosphatase activity) |
2021-03-28 | Deleted | RELATION | is a GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups) |
2018-07-18 | Added | RELATION | is a GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups) |
2018-07-18 | Deleted | RELATION | is a GO:0003824 (catalytic activity) |
2011-04-07 | Added | RELATION | part of GO:0016120 (carotene biosynthetic process) |
2008-04-01 | Updated | RELATION | is a GO:0003824 (catalytic activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-28 | Added | XREF | RHEA:34479 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-04-04 | Added | CONSTRAINT | in_taxon NCBITaxon:33090 (Viridiplantae) |
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