This term is obsolete.

GO:0046914 JSON

transition metal ion binding

Molecular Function

Definition (GO:0046914 GONUTS page)

Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

11,391,901 annotations

Ancestor Chart

Ancestor chart for GO:0046914
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046914

Child Term Relationship to
GO:0046914
iron ion binding
is_a
copper ion binding
is_a
nickel cation binding
is_a
cadmium ion binding
is_a
zinc ion binding
is_a
vanadium ion binding
is_a
manganese ion binding
is_a
molybdenum ion binding
is_a
mercury ion binding
is_a
cobalt ion binding
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P9WGE9 83332 SODC_MYCTU GO:0046872 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15155722

Cross-references

Database ID Description
InterPro IPR001367 Iron dependent repressor, metal binding and dimerisation domain
InterPro IPR003168 Nitrile hydratase, beta subunit
InterPro IPR004232 Nitrile hydratase alpha/Thiocyanate hydrolase gamma
InterPro IPR007167 Ferrous iron transporter FeoA-like domain
InterPro IPR011178 Amyloidogenic glycoprotein, copper-binding
InterPro IPR017416 Chaperonin Cpn20
InterPro IPR017550 Formylmethanofuran dehydrogenase subunit C
InterPro IPR018141 Nitrile hydratase, alpha subunit
InterPro IPR022689 Iron dependent repressor
InterPro IPR034325 S-100

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:33515 transition element cation

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0046914 based on ALL annotations
The top 100 of 716 co-occurring terms
Co-occurring Term PR S% #Together #Compared
transition metal ion binding
1,011.95 100.00 195,815 195,815
initiator methionyl aminopeptidase activity
783.97 27.61 58,781 75,875
metalloexopeptidase activity
387.00 23.66 75,001 196,116
metalloaminopeptidase activity
247.87 16.20 63,347 258,623
plasma membrane copper ion transport
624.85 11.34 23,887 38,685
aminopeptidase activity
139.78 11.30 75,001 542,987
copper ion export
603.60 11.27 23,888 40,049
nitrile hydratase activity
743.70 3.57 7,089 9,646
protein dimerization activity
39.90 3.34 35,345 896,340
cell envelope
35.46 2.80 23,842 680,335
Totals 1134131 149197692
No co-occurrence statistics for GO:0046914 based on MANUAL annotations
The top 100 of 158 co-occurring terms
Co-occurring Term PR S% #Together #Compared
transition metal ion binding
38,149.54 100.00 37 37
cell envelope
17,066.90 29.31 17 38
plasma membrane copper ion transport
14,739.60 26.56 17 44
copper ion export
7,228.33 15.79 18 95
PTW/PP1 phosphatase complex
2,543.30 4.96 6 90
silver ion transmembrane transport
7,629.91 4.44 2 10
regulation of translational initiation in response to stress
6,358.26 4.26 2 12
copper ion transmembrane transport
4,015.74 3.70 2 19
response to silver ion
2,825.89 3.23 2 27
telomere maintenance in response to DNA damage
2,179.97 2.86 2 35
Totals 273 37437

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2021-05-24 Added DEFINITION Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-07-03 Deleted DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-06-25 Deleted RELATION is a GO:0043169 (cation binding)
2008-05-13 Added DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2008-05-12 Deleted DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2008-04-01 Updated RELATION is a GO:0046872 (metal ion binding)
2008-04-01 Updated RELATION is a GO:0043169 (cation binding)
2003-06-10 Updated TERM transition metal ion binding
Timestamp Action Category Detail
2003-06-10 Updated TERM transition metal ion binding
2003-04-15 Added TERM transition metal ion binding activity
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2021-05-24 Added DEFINITION Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-07-03 Deleted DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2008-05-13 Added DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2008-05-12 Deleted DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2003-04-15 Added DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
Timestamp Action Category Detail
2009-06-25 Deleted RELATION is a GO:0043169 (cation binding)
2008-04-01 Updated RELATION is a GO:0046872 (metal ion binding)
2008-04-01 Updated RELATION is a GO:0043169 (cation binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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