This term is obsolete.

GO:0046914 JSON

transition metal ion binding

Molecular Function

Definition (GO:0046914 GONUTS page)

Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

8,293,893 annotations

Ancestor Chart

Ancestor chart for GO:0046914
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046914

Child Term Relationship to
GO:0046914
molybdenum ion binding
is_a
zinc ion binding
is_a
mercury ion binding
is_a
nickel cation binding
is_a
vanadium ion binding
is_a
cobalt ion binding
is_a
cadmium ion binding
is_a
manganese ion binding
is_a
copper ion binding
is_a
iron ion binding
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P9WGE9 83332 SODC_MYCTU GO:0046872 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15155722

Cross-references

Database ID Description
InterPro IPR001367 Iron dependent repressor, metal binding and dimerisation domain
InterPro IPR003168 Nitrile hydratase, beta subunit
InterPro IPR004232 Nitrile hydratase alpha/Thiocyanate hydrolase gamma
InterPro IPR007167 Ferrous iron transporter FeoA-like domain
InterPro IPR011178 Amyloidogenic glycoprotein, copper-binding
InterPro IPR017416 Chaperonin Cpn20
InterPro IPR017550 Formylmethanofuran dehydrogenase subunit C
InterPro IPR018141 Nitrile hydratase, alpha subunit
InterPro IPR022689 Iron dependent repressor
InterPro IPR034325 S-100

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:33515 transition element cation

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0046914 based on ALL annotations
The top 100 of 680 co-occurring terms
Co-occurring Term PR S% #Together #Compared
transition metal ion binding
1,633.45 100.00 119,342 119,342
plasma membrane copper ion transport
1,009.24 17.67 23,677 38,321
copper ion export
975.68 17.50 23,678 39,641
nitrile hydratase activity
1,211.73 5.72 6,965 9,389
protein dimerization activity
67.88 3.78 34,833 838,193
axonogenesis
225.68 3.69 5,711 41,335
central nervous system development
194.01 3.53 5,699 47,982
heparin binding
134.13 3.28 6,185 75,322
calcium-dependent protein binding
329.05 3.15 4,298 21,336
cell envelope
55.69 3.00 23,632 693,121
Totals 550417 96022921
No co-occurrence statistics for GO:0046914 based on MANUAL annotations
The top 100 of 155 co-occurring terms
Co-occurring Term PR S% #Together #Compared
transition metal ion binding
33,994.71 100.00 38 38
cell envelope
14,230.34 28.57 18 43
plasma membrane copper ion transport
12,487.85 26.09 18 49
copper ion export
8,175.94 19.39 19 79
PTW/PP1 phosphatase complex
2,428.19 5.17 6 84
silver ion transmembrane transport
6,798.94 4.35 2 10
regulation of translational initiation in response to stress
6,798.94 4.35 2 10
copper ion transmembrane transport
3,399.47 3.57 2 20
response to silver ion
2,518.13 3.17 2 27
cadherin binding involved in cell-cell adhesion
2,060.29 2.90 2 33
Totals 278 36453

Change Log

Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-07-03 Deleted DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-06-25 Deleted RELATION is a GO:0043169 (cation binding)
2008-05-13 Added DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2008-05-12 Deleted DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2008-04-01 Updated RELATION is a GO:0046872 (metal ion binding)
2008-04-01 Updated RELATION is a GO:0043169 (cation binding)
2003-06-10 Updated TERM transition metal ion binding
Timestamp Action Category Detail
2003-06-10 Updated TERM transition metal ion binding
2003-04-15 Added TERM transition metal ion binding activity
Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-07-03 Deleted DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2008-05-13 Added DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2008-05-12 Deleted DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
2003-04-15 Added DEFINITION Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
Timestamp Action Category Detail
2009-06-25 Deleted RELATION is a GO:0043169 (cation binding)
2008-04-01 Updated RELATION is a GO:0046872 (metal ion binding)
2008-04-01 Updated RELATION is a GO:0043169 (cation binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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