GO:0047376
JSON
all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity
Molecular Function
Definition (GO:0047376 GONUTS page)
Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
all-trans-retinyl-palmitate hydrolase activity | broad |
all-trans-retinyl-palmitate acylhydrolase activity | broad |
retinyl-palmitate palmitohydrolase activity | broad |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0047376 | all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity | Never in Taxon | 4895 | Schizosaccharomyces |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q6DFZ6 | 7955 | NOT1B_DANRE | GO:0052689 | To remove over-annotation from InterPro entries; Eukaryotic TrEmbl proteins are false positives probably due to low quality sequences. Reported by InterPro on 21st April 2015. | IPR004963 |
NOT-qualified manual | protein | E9PTA2 | 10116 | TRPM2_RAT | GO:0016787 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | O94759 | 9606 | TRPM2_HUMAN | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | P33438 | 7227 | GLT_DROME | GO:0052689 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:2108864 | |
NOT-qualified manual | protein | Q62226 | 10090 | SHH_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113 | |
NOT-qualified manual | protein | Q63673 | 10116 | SHH_RAT | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
KEGG_REACTION | R02368 | |
MetaCyc | 3.1.1.64-RXN | |
RHEA | 13933 | |
Reactome | R-HSA-2404140 | |
Reactome | R-HSA-2429643 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15377 | water |
has_participant | CHEBI | CHEBI:17616 | all-trans-retinyl palmitate |
has_participant | CHEBI | CHEBI:7896 | hexadecanoate |
has_participant | CHEBI | CHEBI:17336 | all-trans-retinol |
has_participant | CHEBI | CHEBI:15378 | hydron |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0047376 based on ALL annotations
The top 88 of 88 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity
|
1,422,910.80 | 100.00 | 137 | 137 |
short-chain fatty acid catabolic process
|
213,436.62 | 1.95 | 3 | 20 |
fatty-acyl-ethyl-ester synthase activity
|
1,422,910.80 | 1.46 | 2 | 2 |
acylcarnitine hydrolase activity
|
948,607.25 | 1.45 | 2 | 3 |
cytosolic lipolysis
|
355,727.70 | 1.40 | 2 | 8 |
trans-permethrin hydrolase activity
|
29,187.92 | 1.22 | 4 | 195 |
lipoprotein lipase activity
|
16,626.76 | 1.16 | 88 | 7,531 |
ether lipid metabolic process
|
21,397.15 | 1.13 | 6 | 399 |
retinol metabolic process
|
15,371.30 | 1.08 | 137 | 12,682 |
cold-induced thermogenesis
|
45,171.77 | 1.01 | 2 | 63 |
Totals | 1467 | 178011726 |
No co-occurrence statistics for GO:0047376 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Totals | 0 | 0 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
2023-03-06 | Deleted | RELATION | part of GO:0042572 (retinol metabolic process) |
2023-03-06 | Added | RELATION | is a GO:0050253 (retinyl-palmitate esterase activity) |
2023-03-06 | Deleted | RELATION | is a GO:0052689 (carboxylic ester hydrolase activity) |
2021-04-20 | Deleted | XREF | EC:3.1.1.- |
2021-01-04 | Deleted | XREF | EC:3.1.1 |
2021-01-04 | Added | XREF | EC:3.1.1.- |
2019-06-20 | Deleted | XREF | KEGG:R02368 |
2019-06-20 | Added | XREF | KEGG_REACTION:R02368 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2429643 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-03-01 | Updated | TERM | all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity |
2003-08-19 | Added | TERM | all-trans-retinyl-palmitate hydrolase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-03-01 | Deleted | DEFINITION | Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol. |
2012-03-01 | Added | DEFINITION | Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate. |
2012-03-01 | Added | SYNONYM | retinyl-palmitate palmitohydrolase activity |
2012-03-01 | Added | SYNONYM | all-trans-retinyl-palmitate acylhydrolase activity |
2012-03-01 | Added | SYNONYM | all-trans-retinyl-palmitate hydrolase activity |
2012-03-01 | Deleted | SYNONYM | all-trans-retinyl-palmitate acylhydrolase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol. |
2007-11-08 | Added | SYNONYM | all-trans-retinyl-palmitate acylhydrolase activity |
2006-01-24 | Updated | DEFINITION | Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol. |
2003-08-19 | Added | DEFINITION | Catalysis of the reaction: H2O + retinol-palmitate = palmitate + Retinol. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-03-06 | Deleted | RELATION | part of GO:0042572 (retinol metabolic process) |
2023-03-06 | Added | RELATION | is a GO:0050253 (retinyl-palmitate esterase activity) |
2023-03-06 | Deleted | RELATION | is a GO:0052689 (carboxylic ester hydrolase activity) |
2013-09-25 | Added | RELATION | part of GO:0042572 (retinol metabolic process) |
2011-05-03 | Added | RELATION | is a GO:0052689 (carboxylic ester hydrolase activity) |
2011-05-03 | Deleted | RELATION | is a GO:0004091 (carboxylesterase activity) |
2008-04-01 | Updated | RELATION | is a GO:0004091 (carboxylesterase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-04-20 | Deleted | XREF | EC:3.1.1.- |
2021-01-04 | Deleted | XREF | EC:3.1.1 |
2021-01-04 | Added | XREF | EC:3.1.1.- |
2019-06-20 | Deleted | XREF | KEGG:R02368 |
2019-06-20 | Added | XREF | KEGG_REACTION:R02368 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2429643 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2404140 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2404140 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2429643 |
2018-12-11 | Added | XREF | reactome:R-HSA-2404140 |
2018-12-11 | Added | XREF | reactome:R-HSA-2429643 |
2018-07-13 | Deleted | XREF | RHEA:13936 |
2018-07-13 | Added | XREF | RHEA:13933 |
2016-10-03 | Added | XREF | EC:3.1.1 |
2016-10-03 | Deleted | XREF | EC:3.1.1.- |
2012-03-01 | Added | XREF | EC:3.1.1.- |
2012-03-01 | Deleted | XREF | EC:3.1.1.64 |
2012-03-01 | Added | XREF | KEGG:R02368 |
2011-09-16 | Added | XREF | RHEA:13936 |
2003-10-27 | Added | XREF | MetaCyc:3.1.1.64-RXN |
2003-08-19 | Added | XREF | EC:3.1.1.64 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
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