This term is obsolete.

GO:0047376 JSON

all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity

Molecular Function

Definition (GO:0047376 GONUTS page)

Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.

137 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
all-trans-retinyl-palmitate hydrolase activity broad
all-trans-retinyl-palmitate acylhydrolase activity broad
retinyl-palmitate palmitohydrolase activity broad

Ancestor Chart

Ancestor chart for GO:0047376
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity Never in Taxon 4895 Schizosaccharomyces

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q6DFZ6 7955 NOT1B_DANRE GO:0052689 To remove over-annotation from InterPro entries; Eukaryotic TrEmbl proteins are false positives probably due to low quality sequences. Reported by InterPro on 21st April 2015. IPR004963
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein P33438 7227 GLT_DROME GO:0052689 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:2108864
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
KEGG_REACTION R02368
MetaCyc 3.1.1.64-RXN
RHEA 13933
Reactome R-HSA-2404140
Reactome R-HSA-2429643

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:17616 all-trans-retinyl palmitate
has_participant CHEBI CHEBI:7896 hexadecanoate
has_participant CHEBI CHEBI:17336 all-trans-retinol
has_participant CHEBI CHEBI:15378 hydron

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0047376 based on ALL annotations
The top 88 of 88 co-occurring terms
Co-occurring Term PR S% #Together #Compared
all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity
1,422,910.80 100.00 137 137
short-chain fatty acid catabolic process
213,436.62 1.95 3 20
fatty-acyl-ethyl-ester synthase activity
1,422,910.80 1.46 2 2
acylcarnitine hydrolase activity
948,607.25 1.45 2 3
cytosolic lipolysis
355,727.70 1.40 2 8
trans-permethrin hydrolase activity
29,187.92 1.22 4 195
lipoprotein lipase activity
16,626.76 1.16 88 7,531
ether lipid metabolic process
21,397.15 1.13 6 399
retinol metabolic process
15,371.30 1.08 137 12,682
cold-induced thermogenesis
45,171.77 1.01 2 63
Totals 1467 178011726
No co-occurrence statistics for GO:0047376 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Totals 0 0

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2023-03-06 Deleted RELATION part of GO:0042572 (retinol metabolic process)
2023-03-06 Added RELATION is a GO:0050253 (retinyl-palmitate esterase activity)
2023-03-06 Deleted RELATION is a GO:0052689 (carboxylic ester hydrolase activity)
2021-04-20 Deleted XREF EC:3.1.1.-
2021-01-04 Deleted XREF EC:3.1.1
2021-01-04 Added XREF EC:3.1.1.-
2019-06-20 Deleted XREF KEGG:R02368
2019-06-20 Added XREF KEGG_REACTION:R02368
2019-04-01 Added XREF Reactome:R-HSA-2429643
Timestamp Action Category Detail
2012-03-01 Updated TERM all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity
2003-08-19 Added TERM all-trans-retinyl-palmitate hydrolase activity
Timestamp Action Category Detail
2012-03-01 Deleted DEFINITION Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol.
2012-03-01 Added DEFINITION Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.
2012-03-01 Added SYNONYM retinyl-palmitate palmitohydrolase activity
2012-03-01 Added SYNONYM all-trans-retinyl-palmitate acylhydrolase activity
2012-03-01 Added SYNONYM all-trans-retinyl-palmitate hydrolase activity
2012-03-01 Deleted SYNONYM all-trans-retinyl-palmitate acylhydrolase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol.
2007-11-08 Added SYNONYM all-trans-retinyl-palmitate acylhydrolase activity
2006-01-24 Updated DEFINITION Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol.
2003-08-19 Added DEFINITION Catalysis of the reaction: H2O + retinol-palmitate = palmitate + Retinol.
Timestamp Action Category Detail
2023-03-06 Deleted RELATION part of GO:0042572 (retinol metabolic process)
2023-03-06 Added RELATION is a GO:0050253 (retinyl-palmitate esterase activity)
2023-03-06 Deleted RELATION is a GO:0052689 (carboxylic ester hydrolase activity)
2013-09-25 Added RELATION part of GO:0042572 (retinol metabolic process)
2011-05-03 Added RELATION is a GO:0052689 (carboxylic ester hydrolase activity)
2011-05-03 Deleted RELATION is a GO:0004091 (carboxylesterase activity)
2008-04-01 Updated RELATION is a GO:0004091 (carboxylesterase activity)
Timestamp Action Category Detail
2021-04-20 Deleted XREF EC:3.1.1.-
2021-01-04 Deleted XREF EC:3.1.1
2021-01-04 Added XREF EC:3.1.1.-
2019-06-20 Deleted XREF KEGG:R02368
2019-06-20 Added XREF KEGG_REACTION:R02368
2019-04-01 Added XREF Reactome:R-HSA-2429643
2019-04-01 Added XREF Reactome:R-HSA-2404140
2019-04-01 Deleted XREF reactome:R-HSA-2404140
2019-04-01 Deleted XREF reactome:R-HSA-2429643
2018-12-11 Added XREF reactome:R-HSA-2404140
2018-12-11 Added XREF reactome:R-HSA-2429643
2018-07-13 Deleted XREF RHEA:13936
2018-07-13 Added XREF RHEA:13933
2016-10-03 Added XREF EC:3.1.1
2016-10-03 Deleted XREF EC:3.1.1.-
2012-03-01 Added XREF EC:3.1.1.-
2012-03-01 Deleted XREF EC:3.1.1.64
2012-03-01 Added XREF KEGG:R02368
2011-09-16 Added XREF RHEA:13936
2003-10-27 Added XREF MetaCyc:3.1.1.64-RXN
2003-08-19 Added XREF EC:3.1.1.64
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
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