GO:0047390
JSON
glycerophosphocholine cholinephosphodiesterase activity
Molecular Function
Definition (GO:0047390 GONUTS page)
Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
sn-glycero-3-phosphocholine cholinephosphohydrolase activity | related |
L-3-glycerylphosphinicocholine cholinephosphohydrolase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | E9PTA2 | 10116 | TRPM2_RAT | GO:0016787 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | O94759 | 9606 | TRPM2_HUMAN | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q62226 | 10090 | SHH_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113 | |
NOT-qualified manual | protein | Q63673 | 10116 | SHH_RAT | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q91YD4 | 10090 | TRPM2_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q9NHA8 | 7227 | BGBP3_DROME | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10827089 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 3.1.4.38 | |
KEGG_REACTION | R02591 | |
MetaCyc | 3.1.4.38-RXN | |
RHEA | 19545 | |
Reactome | R-HSA-6814797 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:17754 | glycerol |
has_participant | CHEBI | CHEBI:15377 | water |
has_participant | CHEBI | CHEBI:295975 | choline phosphate(1-) |
has_participant | CHEBI | CHEBI:16870 | choline alfoscerate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0047390 based on ALL annotations
The top 20 of 20 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glycerophosphocholine cholinephosphodiesterase activity
|
250,511.84 | 100.00 | 791 | 791 |
choline metabolic process
|
16,416.44 | 6.47 | 662 | 10,102 |
glycerophosphodiester phosphodiesterase activity
|
5,109.49 | 2.03 | 662 | 32,457 |
side of membrane
|
1,316.96 | 0.53 | 769 | 146,279 |
lipid catabolic process
|
433.01 | 0.17 | 770 | 445,475 |
lipid metabolic process
|
147.12 | 0.06 | 662 | 1,127,241 |
phosphoric diester hydrolase activity
|
92.45 | 0.04 | 105 | 284,508 |
phosphatidylcholine phospholipase C activity
|
24.42 | 0.01 | 1 | 10,257 |
alkaline phosphatase activity
|
13.53 | 0.01 | 2 | 37,027 |
extracellular region
|
9.72 | 0.00 | 102 | 2,628,559 |
Totals | 5346 | 116921190 |
No co-occurrence statistics for GO:0047390 based on MANUAL annotations
The top 10 of 10 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glycerophosphocholine cholinephosphodiesterase activity
|
156,837.00 | 100.00 | 9 | 9 |
choline metabolic process
|
7,252.58 | 4.60 | 8 | 173 |
glycerophosphodiester phosphodiesterase activity
|
2,086.52 | 1.32 | 6 | 451 |
phosphoric diester hydrolase activity
|
891.84 | 0.57 | 7 | 1,231 |
lipid metabolic process
|
509.42 | 0.32 | 8 | 2,463 |
glycerophospholipid catabolic process
|
321.39 | 0.20 | 1 | 488 |
extracellular exosome
|
58.13 | 0.04 | 1 | 2,698 |
extracellular region
|
30.71 | 0.02 | 2 | 10,215 |
plasma membrane
|
8.65 | 0.01 | 8 | 144,998 |
protein binding
|
3.75 | 0.00 | 1 | 41,833 |
Totals | 51 | 204559 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+). |
2020-10-08 | Deleted | SYNONYM | sn-glycero-3-phosphocholine cholinephosphohydrolase activity |
2020-10-08 | Added | SYNONYM | sn-glycero-3-phosphocholine cholinephosphohydrolase activity |
2020-10-08 | Added | SYNONYM | L-3-glycerylphosphinicocholine cholinephosphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | L-3-glycerylphosphinicocholine cholinephosphohydrolase activity |
2019-06-20 | Added | XREF | KEGG_REACTION:R02591 |
2019-06-20 | Deleted | XREF | KEGG:R02591 |
2019-04-01 | Added | XREF | Reactome:R-HSA-6814797 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-6814797 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-08-19 | Added | TERM | glycerophosphocholine cholinephosphodiesterase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+). |
2020-10-08 | Deleted | SYNONYM | sn-glycero-3-phosphocholine cholinephosphohydrolase activity |
2020-10-08 | Added | SYNONYM | sn-glycero-3-phosphocholine cholinephosphohydrolase activity |
2020-10-08 | Added | SYNONYM | L-3-glycerylphosphinicocholine cholinephosphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | L-3-glycerylphosphinicocholine cholinephosphohydrolase activity |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = phosphoryl-choline + glycerol. |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+). |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = phosphoryl-choline + glycerol. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = phosphoryl-choline + glycerol. |
2007-11-08 | Added | SYNONYM | L-3-glycerylphosphinicocholine cholinephosphohydrolase activity |
2007-11-08 | Added | SYNONYM | sn-glycero-3-phosphocholine cholinephosphohydrolase activity |
2003-08-19 | Added | DEFINITION | Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = phosphoryl-choline + glycerol. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0008081 (phosphoric diester hydrolase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Added | XREF | KEGG_REACTION:R02591 |
2019-06-20 | Deleted | XREF | KEGG:R02591 |
2019-04-01 | Added | XREF | Reactome:R-HSA-6814797 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-6814797 |
2018-12-11 | Added | XREF | reactome:R-HSA-6814797 |
2018-07-13 | Deleted | XREF | RHEA:19548 |
2018-07-13 | Added | XREF | RHEA:19545 |
2010-10-11 | Added | XREF | RHEA:19548 |
2010-10-11 | Added | XREF | KEGG:R02591 |
2003-10-27 | Added | XREF | MetaCyc:3.1.4.38-RXN |
2003-08-19 | Added | XREF | EC:3.1.4.38 |
Timestamp | Action | Category | Detail |
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