This term is obsolete.

GO:0047390 JSON

glycerophosphocholine cholinephosphodiesterase activity

Molecular Function

Definition (GO:0047390 GONUTS page)

Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+.

808 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
sn-glycero-3-phosphocholine cholinephosphohydrolase activity related
L-3-glycerylphosphinicocholine cholinephosphohydrolase activity related

Ancestor Chart

Ancestor chart for GO:0047390
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q91YD4 10090 TRPM2_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q9NHA8 7227 BGBP3_DROME GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10827089

Cross-references

Database ID Description
EC 3.1.4.38
KEGG_REACTION R02591
MetaCyc 3.1.4.38-RXN
RHEA 19545
Reactome R-HSA-6814797

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:17754 glycerol
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:295975 choline phosphate(1-)
has_participant CHEBI CHEBI:16870 choline alfoscerate

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0047390 based on ALL annotations
The top 20 of 20 co-occurring terms
Co-occurring Term PR S% #Together #Compared
glycerophosphocholine cholinephosphodiesterase activity
250,511.84 100.00 791 791
choline metabolic process
16,416.44 6.47 662 10,102
glycerophosphodiester phosphodiesterase activity
5,109.49 2.03 662 32,457
side of membrane
1,316.96 0.53 769 146,279
lipid catabolic process
433.01 0.17 770 445,475
lipid metabolic process
147.12 0.06 662 1,127,241
phosphoric diester hydrolase activity
92.45 0.04 105 284,508
phosphatidylcholine phospholipase C activity
24.42 0.01 1 10,257
alkaline phosphatase activity
13.53 0.01 2 37,027
extracellular region
9.72 0.00 102 2,628,559
Totals 5346 116921190
No co-occurrence statistics for GO:0047390 based on MANUAL annotations
The top 10 of 10 co-occurring terms
Co-occurring Term PR S% #Together #Compared
glycerophosphocholine cholinephosphodiesterase activity
156,837.00 100.00 9 9
choline metabolic process
7,252.58 4.60 8 173
glycerophosphodiester phosphodiesterase activity
2,086.52 1.32 6 451
phosphoric diester hydrolase activity
891.84 0.57 7 1,231
lipid metabolic process
509.42 0.32 8 2,463
glycerophospholipid catabolic process
321.39 0.20 1 488
extracellular exosome
58.13 0.04 1 2,698
extracellular region
30.71 0.02 2 10,215
plasma membrane
8.65 0.01 8 144,998
protein binding
3.75 0.00 1 41,833
Totals 51 204559

Change Log

Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+).
2020-10-08 Deleted SYNONYM sn-glycero-3-phosphocholine cholinephosphohydrolase activity
2020-10-08 Added SYNONYM sn-glycero-3-phosphocholine cholinephosphohydrolase activity
2020-10-08 Added SYNONYM L-3-glycerylphosphinicocholine cholinephosphohydrolase activity
2020-10-08 Deleted SYNONYM L-3-glycerylphosphinicocholine cholinephosphohydrolase activity
2019-06-20 Added XREF KEGG_REACTION:R02591
2019-06-20 Deleted XREF KEGG:R02591
2019-04-01 Added XREF Reactome:R-HSA-6814797
2019-04-01 Deleted XREF reactome:R-HSA-6814797
Timestamp Action Category Detail
2003-08-19 Added TERM glycerophosphocholine cholinephosphodiesterase activity
Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+).
2020-10-08 Deleted SYNONYM sn-glycero-3-phosphocholine cholinephosphohydrolase activity
2020-10-08 Added SYNONYM sn-glycero-3-phosphocholine cholinephosphohydrolase activity
2020-10-08 Added SYNONYM L-3-glycerylphosphinicocholine cholinephosphohydrolase activity
2020-10-08 Deleted SYNONYM L-3-glycerylphosphinicocholine cholinephosphohydrolase activity
2010-10-11 Deleted DEFINITION Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = phosphoryl-choline + glycerol.
2010-10-11 Added DEFINITION Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+).
2008-05-13 Added DEFINITION Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = phosphoryl-choline + glycerol.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = phosphoryl-choline + glycerol.
2007-11-08 Added SYNONYM L-3-glycerylphosphinicocholine cholinephosphohydrolase activity
2007-11-08 Added SYNONYM sn-glycero-3-phosphocholine cholinephosphohydrolase activity
2003-08-19 Added DEFINITION Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = phosphoryl-choline + glycerol.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008081 (phosphoric diester hydrolase activity)
Timestamp Action Category Detail
2019-06-20 Added XREF KEGG_REACTION:R02591
2019-06-20 Deleted XREF KEGG:R02591
2019-04-01 Added XREF Reactome:R-HSA-6814797
2019-04-01 Deleted XREF reactome:R-HSA-6814797
2018-12-11 Added XREF reactome:R-HSA-6814797
2018-07-13 Deleted XREF RHEA:19548
2018-07-13 Added XREF RHEA:19545
2010-10-11 Added XREF RHEA:19548
2010-10-11 Added XREF KEGG:R02591
2003-10-27 Added XREF MetaCyc:3.1.4.38-RXN
2003-08-19 Added XREF EC:3.1.4.38
Timestamp Action Category Detail
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