GO:0047559
JSON
3-dehydro-L-gulonate 2-dehydrogenase activity
Molecular Function
Definition (GO:0047559 GONUTS page)
Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
3-keto-L-gulonate dehydrogenase activity | related |
3-ketogulonate dehydrogenase activity | related |
3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity | related |
2,3-diketo-L-gulonate reductase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 5270 | BI1_MYCMD | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4KZV0 | 6945 | A0A1S4KZV0_IXOSC | GO:0016616 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.1.1.130 | |
InterPro | IPR023689 | 2,3-diketo-L-gulonate reductase |
MetaCyc | 3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0047559 based on ALL annotations
The top 6 of 6 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
3-dehydro-L-gulonate 2-dehydrogenase activity
|
154,929.53 | 100.00 | 1,279 | 1,279 |
NAD+ binding
|
505.24 | 0.33 | 851 | 260,954 |
catalytic activity
|
41.33 | 0.03 | 1,242 | 4,655,290 |
oxidoreductase activity
|
16.06 | 0.01 | 1,279 | 12,339,325 |
cytoplasm
|
5.17 | 0.00 | 851 | 25,503,657 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
0.13 | 0.00 | 1 | 1,161,093 |
Totals | 5503 | 43921598 |
No co-occurrence statistics for GO:0047559 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Totals | 0 | 0 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | 3-ketogulonate dehydrogenase activity |
2020-10-08 | Deleted | SYNONYM | 3-keto-L-gulonate dehydrogenase activity |
2020-10-08 | Deleted | SYNONYM | 2,3-diketo-L-gulonate reductase activity |
2020-10-08 | Deleted | SYNONYM | 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity |
2020-10-08 | Added | SYNONYM | 3-ketogulonate dehydrogenase activity |
2020-10-08 | Added | SYNONYM | 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity |
2020-10-08 | Added | SYNONYM | 3-keto-L-gulonate dehydrogenase activity |
2020-10-08 | Added | SYNONYM | 2,3-diketo-L-gulonate reductase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-08-27 | Added | TERM | 3-dehydro-L-gulonate 2-dehydrogenase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | 3-ketogulonate dehydrogenase activity |
2020-10-08 | Deleted | SYNONYM | 3-keto-L-gulonate dehydrogenase activity |
2020-10-08 | Deleted | SYNONYM | 2,3-diketo-L-gulonate reductase activity |
2020-10-08 | Deleted | SYNONYM | 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity |
2020-10-08 | Added | SYNONYM | 3-ketogulonate dehydrogenase activity |
2020-10-08 | Added | SYNONYM | 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity |
2020-10-08 | Added | SYNONYM | 3-keto-L-gulonate dehydrogenase activity |
2020-10-08 | Added | SYNONYM | 2,3-diketo-L-gulonate reductase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+. |
2007-11-08 | Added | SYNONYM | 3-ketogulonate dehydrogenase activity |
2007-11-08 | Added | SYNONYM | 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity |
2007-09-06 | Added | SYNONYM | 2,3-diketo-L-gulonate reductase activity |
2007-09-06 | Added | SYNONYM | 3-keto-L-gulonate dehydrogenase activity |
2003-10-31 | Updated | DEFINITION | Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+. |
2003-10-24 | Updated | DEFINITION | Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P) = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+. |
2003-08-28 | Updated | DEFINITION | Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P) = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H2. |
2003-08-27 | Added | DEFINITION | Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P) = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H2. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-10-27 | Added | XREF | MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN |
2003-08-27 | Added | XREF | EC:1.1.1.130 |
Timestamp | Action | Category | Detail |
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