This term is obsolete.

GO:0047559 JSON

3-dehydro-L-gulonate 2-dehydrogenase activity

Molecular Function

Definition (GO:0047559 GONUTS page)

Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.

1,279 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
3-keto-L-gulonate dehydrogenase activity related
3-ketogulonate dehydrogenase activity related
3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity related
2,3-diketo-L-gulonate reductase activity related

Ancestor Chart

Ancestor chart for GO:0047559
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 5270 BI1_MYCMD GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4KZV0 6945 A0A1S4KZV0_IXOSC GO:0016616 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
EC 1.1.1.130
InterPro IPR023689 2,3-diketo-L-gulonate reductase
MetaCyc 3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0047559 based on ALL annotations
The top 6 of 6 co-occurring terms
Co-occurring Term PR S% #Together #Compared
3-dehydro-L-gulonate 2-dehydrogenase activity
154,929.53 100.00 1,279 1,279
NAD+ binding
505.24 0.33 851 260,954
catalytic activity
41.33 0.03 1,242 4,655,290
oxidoreductase activity
16.06 0.01 1,279 12,339,325
cytoplasm
5.17 0.00 851 25,503,657
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.13 0.00 1 1,161,093
Totals 5503 43921598
No co-occurrence statistics for GO:0047559 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Totals 0 0

Change Log

Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM 3-ketogulonate dehydrogenase activity
2020-10-08 Deleted SYNONYM 3-keto-L-gulonate dehydrogenase activity
2020-10-08 Deleted SYNONYM 2,3-diketo-L-gulonate reductase activity
2020-10-08 Deleted SYNONYM 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity
2020-10-08 Added SYNONYM 3-ketogulonate dehydrogenase activity
2020-10-08 Added SYNONYM 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity
2020-10-08 Added SYNONYM 3-keto-L-gulonate dehydrogenase activity
2020-10-08 Added SYNONYM 2,3-diketo-L-gulonate reductase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.
Timestamp Action Category Detail
2003-08-27 Added TERM 3-dehydro-L-gulonate 2-dehydrogenase activity
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM 3-ketogulonate dehydrogenase activity
2020-10-08 Deleted SYNONYM 3-keto-L-gulonate dehydrogenase activity
2020-10-08 Deleted SYNONYM 2,3-diketo-L-gulonate reductase activity
2020-10-08 Deleted SYNONYM 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity
2020-10-08 Added SYNONYM 3-ketogulonate dehydrogenase activity
2020-10-08 Added SYNONYM 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity
2020-10-08 Added SYNONYM 3-keto-L-gulonate dehydrogenase activity
2020-10-08 Added SYNONYM 2,3-diketo-L-gulonate reductase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.
2007-11-08 Added SYNONYM 3-ketogulonate dehydrogenase activity
2007-11-08 Added SYNONYM 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity
2007-09-06 Added SYNONYM 2,3-diketo-L-gulonate reductase activity
2007-09-06 Added SYNONYM 3-keto-L-gulonate dehydrogenase activity
2003-10-31 Updated DEFINITION Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.
2003-10-24 Updated DEFINITION Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P) = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.
2003-08-28 Updated DEFINITION Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P) = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H2.
2003-08-27 Added DEFINITION Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P) = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H2.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN
2003-08-27 Added XREF EC:1.1.1.130
Timestamp Action Category Detail
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