This term is obsolete.

GO:0047805 JSON

cytidylate cyclase activity

Molecular Function

Definition (GO:0047805 GONUTS page)

Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H+.

5 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
CTP diphosphate-lyase (cyclizing) related
3',5'-cyclic-CMP synthase activity related
cytidylyl cyclase activity related
3'5'-cyclic-CMP synthase activity related
CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming) related
cytidyl cyclase activity related

Ancestor Chart

Ancestor chart for GO:0047805
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 4.6.1.6
KEGG_REACTION R00574
MetaCyc CYTIDYLATE-CYCLASE-RXN
RHEA 14737

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:37563 CTP(4-)
has_participant CHEBI CHEBI:33019 diphosphate(3-)
has_participant CHEBI CHEBI:58003 3',5'-cyclic CMP(1-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0047805 based on ALL annotations
The top 34 of 34 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cytidylate cyclase activity
39,630,972.00 100.00 5 5
retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission
426,139.50 1.03 1 93
cellular response to nitric oxide
330,258.12 0.83 3 360
nitric oxide binding
164,103.42 0.41 4 966
positive regulation of nitric oxide mediated signal transduction
151,263.27 0.38 1 262
nitric oxide mediated signal transduction
147,601.39 0.37 2 537
relaxation of vascular associated smooth muscle
91,105.69 0.23 1 435
nitric oxide-cGMP-mediated signaling
87,340.98 0.22 4 1,815
guanylate cyclase complex, soluble
17,617.68 0.04 4 8,998
response to oxygen levels
12,703.59 0.03 3 9,359
Totals 98 73631364
No co-occurrence statistics for GO:0047805 based on MANUAL annotations
The top 26 of 26 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cytidylate cyclase activity
705,766.50 100.00 2 2
retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission
352,883.25 33.33 1 2
positive regulation of nitric oxide mediated signal transduction
78,418.50 10.00 1 9
nitric oxide binding
39,209.25 5.56 2 36
nitric oxide-cGMP-mediated signaling
27,677.12 3.92 2 51
relaxation of vascular associated smooth muscle
15,016.31 2.08 1 47
response to herbicide
14,703.47 2.04 1 48
cellular response to nitric oxide
9,048.29 1.27 1 78
guanylate cyclase complex, soluble
8,159.15 1.16 2 173
nitric oxide mediated signal transduction
6,987.79 0.98 1 101
Totals 38 150046

Change Log

Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H+.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+).
2020-10-08 Deleted SYNONYM 3',5'-cyclic-CMP synthase activity
2020-10-08 Deleted SYNONYM 3'5'-cyclic-CMP synthase activity
2020-10-08 Deleted SYNONYM cytidyl cyclase activity
2020-10-08 Added SYNONYM 3',5'-cyclic-CMP synthase activity
2020-10-08 Added SYNONYM CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)
2020-10-08 Added SYNONYM 3'5'-cyclic-CMP synthase activity
2020-10-08 Added SYNONYM cytidylyl cyclase activity
2020-10-08 Added SYNONYM CTP diphosphate-lyase (cyclizing)
Timestamp Action Category Detail
2003-08-29 Added TERM cytidylate cyclase activity
Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H+.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+).
2020-10-08 Deleted SYNONYM 3',5'-cyclic-CMP synthase activity
2020-10-08 Deleted SYNONYM 3'5'-cyclic-CMP synthase activity
2020-10-08 Deleted SYNONYM cytidyl cyclase activity
2020-10-08 Added SYNONYM 3',5'-cyclic-CMP synthase activity
2020-10-08 Added SYNONYM CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)
2020-10-08 Added SYNONYM 3'5'-cyclic-CMP synthase activity
2020-10-08 Added SYNONYM cytidylyl cyclase activity
2020-10-08 Added SYNONYM CTP diphosphate-lyase (cyclizing)
2020-10-08 Added SYNONYM cytidyl cyclase activity
2020-10-08 Deleted SYNONYM cytidylyl cyclase activity
2020-10-08 Deleted SYNONYM CTP diphosphate-lyase (cyclizing)
2020-10-08 Deleted SYNONYM CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)
2010-10-11 Deleted DEFINITION Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate.
2010-10-11 Added DEFINITION Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+).
2008-05-13 Added DEFINITION Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate.
2007-11-08 Added SYNONYM CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)
2007-11-08 Added SYNONYM CTP diphosphate-lyase (cyclizing)
2007-11-08 Added SYNONYM 3',5'-cyclic-CMP synthase activity
2007-09-06 Added SYNONYM cytidyl cyclase activity
2007-09-06 Added SYNONYM cytidylyl cyclase activity
2007-09-06 Added SYNONYM 3'5'-cyclic-CMP synthase activity
2003-08-29 Added DEFINITION Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate.
Timestamp Action Category Detail
2011-03-30 Added RELATION part of GO:0009190 (cyclic nucleotide biosynthetic process)
2008-04-01 Updated RELATION is a GO:0016849 (phosphorus-oxygen lyase activity)
2008-04-01 Updated RELATION is a GO:0009975 (cyclase activity)
Timestamp Action Category Detail
2019-06-20 Added XREF KEGG_REACTION:R00574
2019-06-20 Deleted XREF KEGG:R00574
2018-07-13 Added XREF RHEA:14737
2018-07-13 Deleted XREF RHEA:14740
2010-10-11 Added XREF RHEA:14740
2010-10-11 Added XREF KEGG:R00574
2003-10-27 Added XREF MetaCyc:CYTIDYLATE-CYCLASE-RXN
2003-08-29 Added XREF EC:4.6.1.6
Timestamp Action Category Detail
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