GO:0047847
JSON
deoxyuridine phosphorylase activity
Molecular Function
Definition (GO:0047847 GONUTS page)
Catalysis of the reaction: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil.
Ancestor Chart
Ancestor chart for GO:0047847
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016757 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A6KJI3 | 10116 | A6KJI3_RAT | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D6WQD5 | 7070 | D6WQD5_TRICA | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q6AYL7 | 10116 | Q6AYL7_RAT | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7JRM5 | 7227 | Q7JRM5_DROME | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.4.2.2 | |
EC | 2.4.2.3 | |
MetaCyc | URA-PHOSPH-RXN | |
RHEA | 22824 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:16450 | 2'-deoxyuridine |
has_participant | CHEBI | CHEBI:57259 | 2-deoxy-alpha-D-ribose 1-phosphate(2-) |
has_participant | CHEBI | CHEBI:17568 | uracil |
has_participant | CHEBI | CHEBI:43474 | hydrogenphosphate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0047847 based on ALL annotations
The top 94 of 94 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
deoxyuridine phosphorylase activity
|
13,927.18 | 100.00 | 13,997 | 13,997 |
uridine phosphorylase activity
|
7,190.44 | 45.45 | 11,078 | 21,457 |
pyrimidine-nucleoside phosphorylase activity
|
6,028.47 | 35.74 | 9,409 | 21,737 |
guanosine phosphorylase activity
|
12,030.24 | 34.94 | 5,175 | 5,991 |
thymidine phosphorylase activity
|
4,724.27 | 29.31 | 9,559 | 28,180 |
pyrimidine nucleoside metabolic process
|
2,556.67 | 12.99 | 4,305 | 23,451 |
pyrimidine nucleobase metabolic process
|
1,942.21 | 10.68 | 4,380 | 31,408 |
nucleoside catabolic process
|
1,749.41 | 9.40 | 3,801 | 30,260 |
purine-nucleoside phosphorylase activity
|
1,337.00 | 8.32 | 5,387 | 56,115 |
1,4-alpha-oligoglucan phosphorylase activity
|
1,284.02 | 7.67 | 4,380 | 47,508 |
Totals | 126876 | 309457196 |
No co-occurrence statistics for GO:0047847 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
deoxyuridine phosphorylase activity
|
184,542.70 | 100.00 | 7 | 7 |
uridine metabolic process
|
147,634.17 | 50.00 | 4 | 5 |
dCMP catabolic process
|
71,766.61 | 38.89 | 7 | 18 |
CMP catabolic process
|
58,276.65 | 30.00 | 6 | 19 |
UMP catabolic process
|
58,276.65 | 30.00 | 6 | 19 |
dTMP catabolic process
|
46,135.68 | 18.75 | 3 | 12 |
dUMP catabolic process
|
34,601.76 | 15.00 | 3 | 16 |
UMP salvage
|
24,070.79 | 11.11 | 3 | 23 |
thymidine phosphorylase activity
|
19,090.63 | 9.09 | 3 | 29 |
uridine phosphorylase activity
|
15,753.65 | 8.54 | 7 | 82 |
Totals | 81 | 135855 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-11 | Deleted | XREF | MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN |
2024-07-11 | Added | XREF | EC:2.4.2.2 |
2024-07-11 | Added | XREF | MetaCyc:URA-PHOSPH-RXN |
2024-07-11 | Added | XREF | EC:2.4.2.3 |
2024-04-12 | Deleted | SYNONYM | 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity |
2024-04-12 | Deleted | SYNONYM | deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity |
2024-04-12 | Deleted | SYNONYM | deoxyuridine:phosphate deoxy-D-ribosyltransferase activity |
2024-04-12 | Deleted | RELATION | is a GO:0016763 (pentosyltransferase activity) |
2024-04-12 | Added | RELATION | is a GO:0016154 (pyrimidine-nucleoside phosphorylase activity) |
2024-04-12 | Added | DEFINITION | Catalysis of the reaction: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-08-29 | Added | TERM | deoxyuridine phosphorylase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-04-12 | Deleted | SYNONYM | 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity |
2024-04-12 | Deleted | SYNONYM | deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity |
2024-04-12 | Deleted | SYNONYM | deoxyuridine:phosphate deoxy-D-ribosyltransferase activity |
2024-04-12 | Added | DEFINITION | Catalysis of the reaction: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil. |
2024-04-12 | Deleted | DEFINITION | Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate. |
2020-10-08 | Added | SYNONYM | 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity |
2020-10-08 | Added | SYNONYM | deoxyuridine:phosphate deoxy-D-ribosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | deoxyuridine:phosphate deoxy-D-ribosyltransferase activity |
2020-10-08 | Added | SYNONYM | deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate. |
2007-11-08 | Added | SYNONYM | deoxyuridine:phosphate deoxy-D-ribosyltransferase activity |
2007-11-08 | Added | SYNONYM | deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity |
2007-11-08 | Added | SYNONYM | 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity |
2003-08-29 | Added | DEFINITION | Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-04-12 | Deleted | RELATION | is a GO:0016763 (pentosyltransferase activity) |
2024-04-12 | Added | RELATION | is a GO:0016154 (pyrimidine-nucleoside phosphorylase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016763 (pentosyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-11 | Deleted | XREF | MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN |
2024-07-11 | Added | XREF | EC:2.4.2.2 |
2024-07-11 | Added | XREF | MetaCyc:URA-PHOSPH-RXN |
2024-07-11 | Added | XREF | EC:2.4.2.3 |
2024-04-12 | Deleted | XREF | EC:2.4.2.23 |
2018-07-13 | Deleted | XREF | RHEA:22827 |
2018-07-13 | Added | XREF | RHEA:22824 |
2011-09-16 | Added | XREF | RHEA:22827 |
2003-10-27 | Added | XREF | MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN |
2003-08-29 | Added | XREF | EC:2.4.2.23 |
Timestamp | Action | Category | Detail |
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