This term is obsolete.

GO:0047847 JSON

deoxyuridine phosphorylase activity

Molecular Function

Definition (GO:0047847 GONUTS page)

Catalysis of the reaction: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil.

14,005 annotations

Ancestor Chart

Ancestor chart for GO:0047847
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016757 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A6KJI3 10116 A6KJI3_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D6WQD5 7070 D6WQD5_TRICA GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q6AYL7 10116 Q6AYL7_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7JRM5 7227 Q7JRM5_DROME GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 2.4.2.2
EC 2.4.2.3
MetaCyc URA-PHOSPH-RXN
RHEA 22824

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:16450 2'-deoxyuridine
has_participant CHEBI CHEBI:57259 2-deoxy-alpha-D-ribose 1-phosphate(2-)
has_participant CHEBI CHEBI:17568 uracil
has_participant CHEBI CHEBI:43474 hydrogenphosphate

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0047847 based on ALL annotations
The top 94 of 94 co-occurring terms
Co-occurring Term PR S% #Together #Compared
deoxyuridine phosphorylase activity
13,927.18 100.00 13,997 13,997
uridine phosphorylase activity
7,190.44 45.45 11,078 21,457
pyrimidine-nucleoside phosphorylase activity
6,028.47 35.74 9,409 21,737
guanosine phosphorylase activity
12,030.24 34.94 5,175 5,991
thymidine phosphorylase activity
4,724.27 29.31 9,559 28,180
pyrimidine nucleoside metabolic process
2,556.67 12.99 4,305 23,451
pyrimidine nucleobase metabolic process
1,942.21 10.68 4,380 31,408
nucleoside catabolic process
1,749.41 9.40 3,801 30,260
purine-nucleoside phosphorylase activity
1,337.00 8.32 5,387 56,115
1,4-alpha-oligoglucan phosphorylase activity
1,284.02 7.67 4,380 47,508
Totals 126876 309457196
No co-occurrence statistics for GO:0047847 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term PR S% #Together #Compared
deoxyuridine phosphorylase activity
184,542.70 100.00 7 7
uridine metabolic process
147,634.17 50.00 4 5
dCMP catabolic process
71,766.61 38.89 7 18
CMP catabolic process
58,276.65 30.00 6 19
UMP catabolic process
58,276.65 30.00 6 19
dTMP catabolic process
46,135.68 18.75 3 12
dUMP catabolic process
34,601.76 15.00 3 16
UMP salvage
24,070.79 11.11 3 23
thymidine phosphorylase activity
19,090.63 9.09 3 29
uridine phosphorylase activity
15,753.65 8.54 7 82
Totals 81 135855

Change Log

Timestamp Action Category Detail
2024-07-11 Deleted XREF MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN
2024-07-11 Added XREF EC:2.4.2.2
2024-07-11 Added XREF MetaCyc:URA-PHOSPH-RXN
2024-07-11 Added XREF EC:2.4.2.3
2024-04-12 Deleted SYNONYM 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity
2024-04-12 Deleted SYNONYM deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity
2024-04-12 Deleted SYNONYM deoxyuridine:phosphate deoxy-D-ribosyltransferase activity
2024-04-12 Deleted RELATION is a GO:0016763 (pentosyltransferase activity)
2024-04-12 Added RELATION is a GO:0016154 (pyrimidine-nucleoside phosphorylase activity)
2024-04-12 Added DEFINITION Catalysis of the reaction: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil.
Timestamp Action Category Detail
2003-08-29 Added TERM deoxyuridine phosphorylase activity
Timestamp Action Category Detail
2024-04-12 Deleted SYNONYM 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity
2024-04-12 Deleted SYNONYM deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity
2024-04-12 Deleted SYNONYM deoxyuridine:phosphate deoxy-D-ribosyltransferase activity
2024-04-12 Added DEFINITION Catalysis of the reaction: 2'-deoxyuridine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + uracil.
2024-04-12 Deleted DEFINITION Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate.
2020-10-08 Added SYNONYM 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity
2020-10-08 Added SYNONYM deoxyuridine:phosphate deoxy-D-ribosyltransferase activity
2020-10-08 Deleted SYNONYM deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity
2020-10-08 Deleted SYNONYM deoxyuridine:phosphate deoxy-D-ribosyltransferase activity
2020-10-08 Added SYNONYM deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity
2020-10-08 Deleted SYNONYM 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate.
2007-11-08 Added SYNONYM deoxyuridine:phosphate deoxy-D-ribosyltransferase activity
2007-11-08 Added SYNONYM deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity
2007-11-08 Added SYNONYM 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity
2003-08-29 Added DEFINITION Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate.
Timestamp Action Category Detail
2024-04-12 Deleted RELATION is a GO:0016763 (pentosyltransferase activity)
2024-04-12 Added RELATION is a GO:0016154 (pyrimidine-nucleoside phosphorylase activity)
2008-04-01 Updated RELATION is a GO:0016763 (pentosyltransferase activity)
Timestamp Action Category Detail
2024-07-11 Deleted XREF MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN
2024-07-11 Added XREF EC:2.4.2.2
2024-07-11 Added XREF MetaCyc:URA-PHOSPH-RXN
2024-07-11 Added XREF EC:2.4.2.3
2024-04-12 Deleted XREF EC:2.4.2.23
2018-07-13 Deleted XREF RHEA:22827
2018-07-13 Added XREF RHEA:22824
2011-09-16 Added XREF RHEA:22827
2003-10-27 Added XREF MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN
2003-08-29 Added XREF EC:2.4.2.23
Timestamp Action Category Detail
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