This term is obsolete.

GO:0047856 JSON

dihydrocoumarin hydrolase activity

Molecular Function

Definition (GO:0047856 GONUTS page)

Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H+.

2 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
dihydrocoumarin lipase activity exact
dihydrocoumarin lactonohydrolase activity related
3,4-dihydrocoumarin hydrolase activity exact

Ancestor Chart

Ancestor chart for GO:0047856
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Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q6DFZ6 7955 NOT1B_DANRE GO:0052689 To remove over-annotation from InterPro entries; Eukaryotic TrEmbl proteins are false positives probably due to low quality sequences. Reported by InterPro on 21st April 2015. IPR004963
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein P33438 7227 GLT_DROME GO:0052689 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:2108864
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 3.1.1.35
KEGG_REACTION R03692
MetaCyc DIHYDROCOUMARIN-LIPASE-RXN
RHEA 10360

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:46957 3-(2-hydroxyphenyl)propanoate
has_participant CHEBI CHEBI:16151 3,4-dihydrocoumarin

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0018733 obsolete 3,4-dihydrocoumarin hydrolase activity replaced_by GO:0047856

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0047856 based on ALL annotations
The top 19 of 19 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0047856
dihydrocoumarin hydrolase activity
99,545,720.00 100.00 2 2
GO:0046226
coumarin catabolic process
16,590,953.00 14.29 1 6
GO:2001038
regulation of cellular response to drug
1,213,972.20 1.20 1 82
GO:0032929
negative regulation of superoxide anion generation
822,691.94 0.82 1 121
GO:1901335
lactone catabolic process
436,604.03 0.44 1 228
GO:0003096
renal sodium ion transport
291,922.94 0.29 1 341
GO:0004063
aryldialkylphosphatase activity
269,771.60 0.27 1 369
GO:0046395
carboxylic acid catabolic process
156,272.72 0.16 1 637
GO:0102007
acyl-L-homoserine-lactone lactonohydrolase activity
76,988.18 0.08 1 1,293
GO:0004064
arylesterase activity
17,833.34 0.02 1 5,582
Totals 21 57288642
No co-occurrence statistics for GO:0047856 based on MANUAL annotations
The top 14 of 14 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0047856
dihydrocoumarin hydrolase activity
1,410,811.00 100.00 1 1
GO:0046226
coumarin catabolic process
282,162.22 20.00 1 5
GO:0102007
acyl-L-homoserine-lactone lactonohydrolase activity
235,135.16 16.67 1 6
GO:1901335
lactone catabolic process
201,544.42 14.29 1 7
GO:0032929
negative regulation of superoxide anion generation
176,351.38 12.50 1 8
GO:2001038
regulation of cellular response to drug
156,756.78 11.11 1 9
GO:0046395
carboxylic acid catabolic process
141,081.11 10.00 1 10
GO:0003096
renal sodium ion transport
88,175.69 6.25 1 16
GO:0004064
arylesterase activity
19,870.58 1.41 1 71
GO:0010124
phenylacetate catabolic process
6,187.77 0.44 1 228
Totals 14 40778

Change Log

Timestamp Action Category Detail
2024-06-27 Added SYNONYM 3,4-dihydrocoumarin hydrolase activity
2022-09-01 Deleted DEFINITION Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+).
2022-09-01 Added DEFINITION Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H+.
2020-10-08 Deleted SYNONYM dihydrocoumarin lactonohydrolase activity
2020-10-08 Added SYNONYM dihydrocoumarin lactonohydrolase activity
2019-06-20 Deleted XREF KEGG:R03692
2019-06-20 Added XREF KEGG_REACTION:R03692
2018-07-13 Deleted XREF RHEA:10363
2018-07-13 Added XREF RHEA:10360
2011-05-03 Added RELATION is a GO:0052689 (carboxylic ester hydrolase activity)
Timestamp Action Category Detail
2003-08-29 Added TERM dihydrocoumarin hydrolase activity
Timestamp Action Category Detail
2024-06-27 Added SYNONYM 3,4-dihydrocoumarin hydrolase activity
2022-09-01 Deleted DEFINITION Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+).
2022-09-01 Added DEFINITION Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H+.
2020-10-08 Deleted SYNONYM dihydrocoumarin lactonohydrolase activity
2020-10-08 Added SYNONYM dihydrocoumarin lactonohydrolase activity
2010-10-11 Added DEFINITION Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+).
2010-10-11 Deleted DEFINITION Catalysis of the reaction: dihydrocoumarin + H2O = melilotate.
2008-05-13 Added DEFINITION Catalysis of the reaction: dihydrocoumarin + H2O = melilotate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: dihydrocoumarin + H2O = melilotate.
2007-11-08 Added SYNONYM dihydrocoumarin lactonohydrolase activity
2007-08-09 Added SYNONYM dihydrocoumarin lipase activity
2007-08-09 Deleted SYNONYM dihydrocoumarin lipase activity
2004-04-19 Added SYNONYM dihydrocoumarin lipase activity
2004-04-16 Deleted SYNONYM dihydrocoumarin lipase activity
2003-10-27 Added SYNONYM dihydrocoumarin lipase activity
2003-08-29 Added DEFINITION Catalysis of the reaction: dihydrocoumarin + H2O = melilotate.
Timestamp Action Category Detail
2011-05-03 Added RELATION is a GO:0052689 (carboxylic ester hydrolase activity)
2011-05-03 Deleted RELATION is a GO:0004091 (carboxylesterase activity)
2008-04-01 Updated RELATION is a GO:0004091 (carboxylesterase activity)
Timestamp Action Category Detail
2019-06-20 Deleted XREF KEGG:R03692
2019-06-20 Added XREF KEGG_REACTION:R03692
2018-07-13 Deleted XREF RHEA:10363
2018-07-13 Added XREF RHEA:10360
2010-10-11 Added XREF KEGG:R03692
2010-10-11 Added XREF RHEA:10363
2003-10-27 Added XREF MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN
2003-08-29 Added XREF EC:3.1.1.35
Timestamp Action Category Detail
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