GO:0048143
JSON
astrocyte activation
Biological Process
Definition (GO:0048143 GONUTS page)
A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. PMID:10526094 PMID:10695728 PMID:12529254 PMID:12580336 PMID:9585813
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0048143
Child Term | Relationship to GO:0048143 |
---|---|
regulation of astrocyte activation
|
regulates |
negative regulation of astrocyte activation
|
negatively_regulates |
astrocyte activation involved in immune response
|
is_a |
positive regulation of astrocyte activation
|
positively_regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0048143 | astrocyte activation | Only in Taxon | 7742 | Vertebrata |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q54NG5 | 44689 | Q54NG5_DICDI | GO:0007417 | To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 | IPR034968 |
IEA Review | protein | Q54NG6 | 44689 | Q54NG6_DICDI | GO:0007417 | To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 | IPR034968 |
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P0CI71 | 10116 | K0319_RAT | GO:0022008 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q2EI20 | 7955 | REST_DANRE | GO:0022008 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:22951640 | |
NOT-qualified manual | protein | Q5SZV5 | 10090 | K0319_MOUSE | GO:0022008 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27510895 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CL | CL:0000127 | astrocyte |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0048143 based on ALL annotations
The top 100 of 1,322 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
astrocyte activation
|
147,457.47 | 100.00 | 1,322 | 1,322 |
microglial cell activation
|
69,190.68 | 29.56 | 587 | 1,251 |
positive regulation of axon regeneration
|
72,031.28 | 26.62 | 488 | 999 |
ciliary neurotrophic factor receptor binding
|
37,265.28 | 17.65 | 488 | 1,931 |
ciliary neurotrophic factor-mediated signaling pathway
|
34,897.79 | 16.85 | 488 | 2,062 |
astrocyte activation involved in immune response
|
142,634.10 | 15.58 | 207 | 214 |
positive regulation of amyloid fibril formation
|
98,782.20 | 14.54 | 207 | 309 |
smooth endoplasmic reticulum calcium ion homeostasis
|
101,409.35 | 13.89 | 196 | 285 |
regulation of spontaneous synaptic transmission
|
103,458.06 | 12.46 | 174 | 248 |
cell surface receptor signaling pathway via STAT
|
27,734.29 | 10.68 | 262 | 1,393 |
Totals | 14504 | 70416 |
No co-occurrence statistics for GO:0048143 based on MANUAL annotations
The top 100 of 1,160 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
astrocyte activation
|
15,563.84 | 100.00 | 83 | 83 |
microglial cell activation
|
5,187.95 | 23.23 | 36 | 108 |
ciliary neurotrophic factor-mediated signaling pathway
|
6,299.65 | 15.74 | 17 | 42 |
ciliary neurotrophic factor receptor binding
|
4,899.73 | 14.17 | 17 | 54 |
neuroinflammatory response
|
5,082.07 | 13.79 | 16 | 49 |
complement-mediated synapse pruning
|
8,093.20 | 13.68 | 13 | 25 |
multivesicular body, internal vesicle lumen
|
14,266.86 | 13.10 | 11 | 12 |
negative regulation of cardiocyte differentiation
|
14,266.86 | 13.10 | 11 | 12 |
response to hydroxyisoflavone
|
14,266.86 | 13.10 | 11 | 12 |
positive regulation of prolactin secretion
|
13,169.41 | 12.94 | 11 | 13 |
Totals | 1131 | 3903 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
2022-01-12 | Added | RELATION | is a GO:0061900 (glial cell activation) |
2022-01-12 | Deleted | RELATION | is a GO:0001775 (cell activation) |
2020-11-03 | Deleted | RELATION | is a GO:0061900 (glial cell activation) |
2020-11-03 | Added | RELATION | is a GO:0001775 (cell activation) |
2017-06-15 | Added | RELATION | is a GO:0061900 (glial cell activation) |
2017-06-15 | Deleted | RELATION | is a GO:0001775 (cell activation) |
2008-05-13 | Added | DEFINITION | A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
2008-05-12 | Deleted | DEFINITION | A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
2008-04-01 | Updated | RELATION | is a GO:0001775 (cell activation) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-07-21 | Added | TERM | astrocyte activation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
2008-05-12 | Deleted | DEFINITION | A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
2003-11-11 | Updated | DEFINITION | A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. |
2003-07-22 | Added | DEFINITION | A change in morphology and behavior of an astrocyte cell resulting from exposure to a mitogen or to an antigen to which they have been primed. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-01-12 | Added | RELATION | is a GO:0061900 (glial cell activation) |
2022-01-12 | Deleted | RELATION | is a GO:0001775 (cell activation) |
2020-11-03 | Deleted | RELATION | is a GO:0061900 (glial cell activation) |
2020-11-03 | Added | RELATION | is a GO:0001775 (cell activation) |
2017-06-15 | Added | RELATION | is a GO:0061900 (glial cell activation) |
2017-06-15 | Deleted | RELATION | is a GO:0001775 (cell activation) |
2008-04-01 | Updated | RELATION | is a GO:0001775 (cell activation) |
2008-04-01 | Updated | RELATION | part of GO:0014002 (astrocyte development) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
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