This term is obsolete.

GO:0048188 JSON

Set1C/COMPASS complex

Cellular Component

Definition (GO:0048188 GONUTS page)

A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30. PMID:11687631 PMID:11742990 PMID:11805083 PMID:12488447 PMID:18508253 PMID:18838538

35,225 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
Set1C exact
Set1/COMPASS complex exact
COMPASS complex exact

Ancestor Chart

Ancestor chart for GO:0048188
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0048188 Set1C/COMPASS complex Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2JW23 10116 A0A0G2JW23_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K8T1 10116 A0A0G2K8T1_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1B0GR71 10090 A0A1B0GR71_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1B0GRK6 10090 A0A1B0GRK6_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5Y8H4 10116 A0A8I5Y8H4_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A0E5 10116 A0A8I6A0E5_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR017111 Histone-lysine N-methyltransferase Set1, fungi
InterPro IPR037353 Histone methyltransferase complex subunit ASH2
InterPro IPR037841 Histone-lysine N-methyltransferase SETD1A/B-like, SET domain
InterPro IPR037850 Retinoblastoma-binding protein 5/Swd1
InterPro IPR037856 Sdc1/DPY30
InterPro IPR037869 Spp1/CFP1

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0048188 based on ALL annotations
The top 100 of 593 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Set1C/COMPASS complex
5,653.68 100.00 34,480 34,480
histone H3K4 methyltransferase activity
1,304.94 11.22 6,180 26,775
nuclear lumen
758.60 6.50 3,865 28,805
methylated histone binding
521.94 5.96 4,968 53,814
histone H3K4 trimethyltransferase activity
2,026.71 3.93 1,459 4,070
histone methyltransferase complex
368.92 1.76 812 12,444
histone binding
109.16 1.70 4,243 219,765
chromatin binding
102.14 1.66 5,880 325,472
chromatin organization
92.17 1.53 6,624 406,314
MLL1/2 complex
4,216.03 1.51 522 700
Totals 142932 25773690
No co-occurrence statistics for GO:0048188 based on MANUAL annotations
The top 100 of 214 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Set1C/COMPASS complex
1,474.66 100.00 876 876
histone H3K4 methyltransferase activity
405.01 9.87 117 426
histone methyltransferase complex
218.82 4.04 46 310
methylated histone binding
71.57 3.13 71 1,463
histone binding
50.11 3.03 191 5,621
transcription initiation-coupled chromatin remodeling
103.26 2.46 32 457
MLL1/2 complex
1,032.26 2.37 21 30
MLL1 complex
126.24 1.98 22 257
MLL3/4 complex
137.35 1.79 19 204
replication fork processing
50.66 1.65 27 786
Totals 2161 138710

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2013-02-13 Deleted RELATION is a GO:0016585 (obsolete chromatin remodeling complex)
2010-11-14 Added DEFINITION A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.
2010-11-14 Deleted DEFINITION A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p.
2010-11-14 Added SYNONYM Set1/COMPASS complex
2009-01-12 Deleted SYNONYM Set1C
2009-01-12 Updated TERM Set1C/COMPASS complex
2009-01-12 Added SYNONYM COMPASS complex
2009-01-12 Added SYNONYM Set1C
2009-01-12 Deleted SYNONYM Set1 complex
Timestamp Action Category Detail
2009-01-12 Updated TERM Set1C/COMPASS complex
2003-08-01 Added TERM COMPASS complex
Timestamp Action Category Detail
2010-11-14 Added DEFINITION A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.
2010-11-14 Deleted DEFINITION A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p.
2010-11-14 Added SYNONYM Set1/COMPASS complex
2009-01-12 Deleted SYNONYM Set1C
2009-01-12 Added SYNONYM COMPASS complex
2009-01-12 Added SYNONYM Set1C
2009-01-12 Deleted SYNONYM Set1 complex
2008-05-13 Added DEFINITION A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p.
2008-05-12 Deleted DEFINITION A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p.
2007-08-09 Deleted SYNONYM Set1C
2007-08-09 Deleted SYNONYM Set1 complex
2007-08-09 Added SYNONYM Set1 complex
2007-08-09 Added SYNONYM Set1C
2004-12-13 Added SYNONYM Set1C
2004-12-13 Added SYNONYM Set1 complex
2004-09-30 Updated DEFINITION A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p.
2003-08-01 Added DEFINITION The COMPASS complex (Complex Proteins Associated with Set1) consists of seven polypeptides, ranging from 130 to 25 kDa, and is related to the trithorax complexes.
Timestamp Action Category Detail
2013-02-13 Deleted RELATION is a GO:0016585 (obsolete chromatin remodeling complex)
2008-04-01 Updated RELATION is a GO:0016585 (obsolete chromatin remodeling complex)
2008-04-01 Updated RELATION is a GO:0035097 (histone methyltransferase complex)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
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