This term is obsolete.

GO:0048709 JSON

oligodendrocyte differentiation

Biological Process

Definition (GO:0048709 GONUTS page)

The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. PMID:15139015

17,199 annotations

Ancestor Chart

Ancestor chart for GO:0048709
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0048709

Child Term Relationship to
GO:0048709
positive regulation of oligodendrocyte differentiation
positively_regulates
oligodendrocyte cell fate commitment
is_a
regulation of oligodendrocyte differentiation
regulates
spinal cord oligodendrocyte cell differentiation
is_a
oligodendrocyte development
part_of
negative regulation of oligodendrocyte differentiation
negatively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0048709 oligodendrocyte differentiation Only in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q54NG5 44689 Q54NG5_DICDI GO:0007417 To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 IPR034968
IEA Review protein Q54NG6 44689 Q54NG6_DICDI GO:0007417 To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 IPR034968
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P0CI71 10116 K0319_RAT GO:0022008 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q2EI20 7955 REST_DANRE GO:0022008 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:22951640
NOT-qualified manual protein Q5SZV5 10090 K0319_MOUSE GO:0022008 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27510895

Cross-references

Database ID Description
InterPro IPR032658 Oligodendrocyte transcription factor 2, basic helix-loop-helix domain

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0000128 oligodendrocyte

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0048709 based on ALL annotations
The top 100 of 2,503 co-occurring terms
Co-occurring Term PR S% #Together #Compared
oligodendrocyte differentiation
33,152.86 100.00 5,880 5,880
positive regulation of chondrocyte differentiation
7,713.68 13.60 1,450 6,232
chondrocyte differentiation
4,408.58 9.68 1,544 11,611
oligodendrocyte cell fate specification
26,541.31 9.27 558 697
negative regulation of oligodendrocyte differentiation
10,672.60 9.27 677 2,103
positive regulation of oligodendrocyte differentiation
10,174.55 8.89 654 2,131
neuron fate commitment
8,311.87 7.97 615 2,453
negative regulation of photoreceptor cell differentiation
25,527.70 7.68 462 600
oligodendrocyte development
5,864.33 6.71 574 3,245
tube development
16,416.27 6.51 410 828
Totals 45129 472263
No co-occurrence statistics for GO:0048709 based on MANUAL annotations
The top 100 of 2,310 co-occurring terms
Co-occurring Term PR S% #Together #Compared
oligodendrocyte differentiation
5,187.95 100.00 249 249
negative regulation of oligodendrocyte differentiation
2,517.68 11.62 33 68
positive regulation of oligodendrocyte differentiation
1,525.87 10.51 35 119
astrocyte differentiation
1,429.33 8.44 27 98
positive regulation of chondrocyte differentiation
1,122.76 8.19 29 134
oligodendrocyte development
951.64 8.01 31 169
neuroblast proliferation
758.62 7.21 31 212
central nervous system myelination
965.20 6.78 24 129
cell maturation
894.47 6.78 25 145
hippocampus development
588.32 6.51 33 291
Totals 1776 14277

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2008-05-13 Added DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2008-05-12 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2008-04-01 Updated RELATION is a GO:0010001 (glial cell differentiation)
2008-04-01 Updated RELATION part of GO:0007417 (central nervous system development)
2005-10-01 Updated DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2005-09-30 Added DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2005-09-29 Added TERM oligodendrocyte differentiation
Timestamp Action Category Detail
2005-09-29 Added TERM oligodendrocyte differentiation
Timestamp Action Category Detail
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2008-05-13 Added DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2008-05-12 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2005-10-01 Updated DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
2005-09-30 Added DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0010001 (glial cell differentiation)
2008-04-01 Updated RELATION part of GO:0007417 (central nervous system development)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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