This term is obsolete.

GO:0050129 JSON

N-formylglutamate deformylase activity

Molecular Function

Definition (GO:0050129 GONUTS page)

Catalysis of the reaction: N-formyl-L-glutamate + H2O = L-glutamate + formate.

1,708 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
formylglutamate deformylase activity related
beta-citryl-L-glutamate hydrolase activity related
beta-citryl-L-glutamate amidase activity related
N-formyl-L-glutamate amidohydrolase activity related
beta-citryl-L-glutamate amidohydrolase activity related
N-formylglutamate hydrolase activity related
beta-citrylglutamate amidase activity related
beta-citryl-L-glutamate-hydrolyzing enzyme related

Ancestor Chart

Ancestor chart for GO:0050129
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q91YD4 10090 TRPM2_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q9NHA8 7227 BGBP3_DROME GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10827089

Cross-references

Database ID Description
EC 3.5.1.68
KEGG_REACTION R00525
MetaCyc N-FORMYLGLUTAMATE-DEFORMYLASE-RXN
RHEA 12476

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15740 formate
has_participant CHEBI CHEBI:17684 N-formyl-L-glutamate(2-)
has_participant CHEBI CHEBI:29985 L-glutamate(1-)
has_participant CHEBI CHEBI:15377 water

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0050129 based on ALL annotations
The top 42 of 42 co-occurring terms
Co-occurring Term PR S% #Together #Compared
N-formylglutamate deformylase activity
114,132.78 100.00 1,708 1,708
N-carbamoyl-L-amino-acid hydrolase activity
172.67 0.08 3 1,983
guanine deaminase activity
92.70 0.07 13 16,006
formimidoylglutamase activity
85.24 0.06 4 5,356
carboxylic acid catabolic process
67.07 0.05 6 10,210
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
42.32 0.04 33 89,005
acylglycerol catabolic process
27.67 0.02 10 41,252
glycerolipid catabolic process
23.37 0.02 4 19,537
epoxide hydrolase activity
21.22 0.02 8 43,031
hydrolase activity
16.73 0.01 1,680 11,461,355
Totals 3710 175536307
No co-occurrence statistics for GO:0050129 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term PR S% #Together #Compared
N-formylglutamate deformylase activity
184,542.70 100.00 7 7
carboxylic acid catabolic process
110,725.63 54.55 6 10
catabolic process
65,132.73 33.33 6 17
carboxypeptidase activity
3,315.14 1.79 6 334
L-histidine catabolic process
1,060.59 0.56 1 174
peptidase activity
670.66 0.36 6 1,651
proteolysis
149.09 0.08 6 7,427
membrane
18.13 0.01 6 61,077
Totals 44 70697

Change Log

Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: N-formyl-L-glutamate + H2O = L-glutamate + formate.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate.
2020-10-08 Added SYNONYM beta-citryl-L-glutamate hydrolase activity
2020-10-08 Added SYNONYM beta-citryl-L-glutamate amidase activity
2020-10-08 Deleted SYNONYM formylglutamate deformylase activity
2020-10-08 Deleted SYNONYM beta-citryl-L-glutamate hydrolase activity
2020-10-08 Deleted SYNONYM beta-citrylglutamate amidase activity
2020-10-08 Deleted SYNONYM beta-citryl-L-glutamate amidohydrolase activity
2020-10-08 Deleted SYNONYM beta-citryl-L-glutamate amidase activity
2020-10-08 Added SYNONYM beta-citrylglutamate amidase activity
Timestamp Action Category Detail
2003-08-29 Added TERM N-formylglutamate deformylase activity
Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: N-formyl-L-glutamate + H2O = L-glutamate + formate.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate.
2020-10-08 Added SYNONYM beta-citryl-L-glutamate hydrolase activity
2020-10-08 Added SYNONYM beta-citryl-L-glutamate amidase activity
2020-10-08 Deleted SYNONYM formylglutamate deformylase activity
2020-10-08 Deleted SYNONYM beta-citryl-L-glutamate hydrolase activity
2020-10-08 Deleted SYNONYM beta-citrylglutamate amidase activity
2020-10-08 Deleted SYNONYM beta-citryl-L-glutamate amidohydrolase activity
2020-10-08 Deleted SYNONYM beta-citryl-L-glutamate amidase activity
2020-10-08 Added SYNONYM beta-citrylglutamate amidase activity
2020-10-08 Added SYNONYM formylglutamate deformylase activity
2020-10-08 Added SYNONYM N-formylglutamate hydrolase activity
2020-10-08 Added SYNONYM beta-citryl-L-glutamate amidohydrolase activity
2020-10-08 Added SYNONYM N-formyl-L-glutamate amidohydrolase activity
2020-10-08 Deleted SYNONYM N-formyl-L-glutamate amidohydrolase activity
2020-10-08 Deleted SYNONYM N-formylglutamate hydrolase activity
2010-10-11 Added DEFINITION Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: N-formyl-L-glutamate + H2O = formate + L-glutamate.
2008-05-13 Added DEFINITION Catalysis of the reaction: N-formyl-L-glutamate + H2O = formate + L-glutamate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: N-formyl-L-glutamate + H2O = formate + L-glutamate.
2007-11-08 Added SYNONYM beta-citryl-L-glutamate amidohydrolase activity
2007-11-08 Added SYNONYM beta-citrylglutamate amidase activity
2007-11-08 Added SYNONYM formylglutamate deformylase activity
2007-11-08 Added SYNONYM beta-citryl-L-glutamate amidase activity
2007-11-08 Added SYNONYM N-formylglutamate hydrolase activity
2007-11-08 Added SYNONYM N-formyl-L-glutamate amidohydrolase activity
2007-11-08 Added SYNONYM beta-citryl-L-glutamate-hydrolyzing enzyme
2007-09-06 Added SYNONYM beta-citryl-L-glutamate hydrolase activity
2003-08-29 Added DEFINITION Catalysis of the reaction: N-formyl-L-glutamate + H2O = formate + L-glutamate.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
Timestamp Action Category Detail
2019-06-20 Added XREF KEGG_REACTION:R00525
2019-06-20 Deleted XREF KEGG:R00525
2018-07-13 Deleted XREF RHEA:12479
2018-07-13 Added XREF RHEA:12476
2010-10-11 Added XREF RHEA:12479
2010-10-11 Added XREF KEGG:R00525
2003-10-27 Added XREF MetaCyc:N-FORMYLGLUTAMATE-DEFORMYLASE-RXN
2003-08-29 Added XREF EC:3.5.1.68
Timestamp Action Category Detail
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