This term is obsolete.

GO:0050415 JSON

formimidoylglutamase activity

Molecular Function

Definition (GO:0050415 GONUTS page)

Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide.

5,357 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
formiminoglutamase activity exact
formiminoglutamate hydrolase activity related
N-formimino-L-glutamate formiminohydrolase activity related
N-formiminoglutamate hydrolase activity related
N-formimidoyl-L-glutamate formimidoylhydrolase activity related

Ancestor Chart

Ancestor chart for GO:0050415
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q91YD4 10090 TRPM2_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q9NHA8 7227 BGBP3_DROME GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10827089

Cross-references

Database ID Description
EC 3.5.3.8
InterPro IPR005923 Formiminoglutamase
KEGG_REACTION R02285
MetaCyc FORMIMINOGLUTAMASE-RXN
RHEA 22492

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:16397 formamide
has_participant CHEBI CHEBI:58928 N-formimidoyl-L-glutamate(1-)
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:29985 L-glutamate(1-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0050415 based on ALL annotations
The top 31 of 31 co-occurring terms
Co-occurring Term PR S% #Together #Compared
formimidoylglutamase activity
36,396.34 100.00 5,356 5,356
putrescine biosynthetic process from arginine, using agmatinase
3,778.75 10.34 5,161 49,710
agmatinase activity
3,772.83 10.33 5,161 49,788
L-histidine catabolic process to glutamate and formamide
2,592.80 7.08 4,967 69,724
L-histidine metabolic process
2,108.07 5.77 5,026 86,775
L-histidine catabolic process to glutamate and formate
2,154.32 5.76 3,644 61,564
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
2,045.44 5.60 5,002 89,005
manganese ion binding
329.61 0.90 4,265 470,951
L-histidine catabolic process
73.36 0.19 142 70,452
N-formylglutamate deformylase activity
85.24 0.06 4 1,708
Totals 49294 212807575
No co-occurrence statistics for GO:0050415 based on MANUAL annotations
The top 4 of 4 co-occurring terms
Co-occurring Term PR S% #Together #Compared
formimidoylglutamase activity
1,291,799.00 100.00 1 1
putrescine biosynthetic process from arginine, using agmatinase
9,097.18 0.70 1 142
agmatinase activity
9,097.18 0.70 1 142
L-histidine catabolic process
7,424.13 0.57 1 174
Totals 4 459

Change Log

Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide.
2020-10-08 Deleted SYNONYM N-formimidoyl-L-glutamate formimidoylhydrolase activity
2020-10-08 Added SYNONYM formiminoglutamate hydrolase activity
2020-10-08 Deleted SYNONYM N-formiminoglutamate hydrolase activity
2020-10-08 Deleted SYNONYM formiminoglutamate hydrolase activity
2020-10-08 Added SYNONYM N-formimino-L-glutamate formiminohydrolase activity
2020-10-08 Deleted SYNONYM N-formimino-L-glutamate formiminohydrolase activity
2020-10-08 Added SYNONYM N-formiminoglutamate hydrolase activity
2020-10-08 Added SYNONYM N-formimidoyl-L-glutamate formimidoylhydrolase activity
Timestamp Action Category Detail
2003-08-30 Added TERM formimidoylglutamase activity
Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide.
2020-10-08 Deleted SYNONYM N-formimidoyl-L-glutamate formimidoylhydrolase activity
2020-10-08 Added SYNONYM formiminoglutamate hydrolase activity
2020-10-08 Deleted SYNONYM N-formiminoglutamate hydrolase activity
2020-10-08 Deleted SYNONYM formiminoglutamate hydrolase activity
2020-10-08 Added SYNONYM N-formimino-L-glutamate formiminohydrolase activity
2020-10-08 Deleted SYNONYM N-formimino-L-glutamate formiminohydrolase activity
2020-10-08 Added SYNONYM N-formiminoglutamate hydrolase activity
2020-10-08 Added SYNONYM N-formimidoyl-L-glutamate formimidoylhydrolase activity
2010-10-11 Added DEFINITION Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide.
2008-05-13 Added DEFINITION Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide.
2007-11-08 Added SYNONYM N-formimidoyl-L-glutamate formimidoylhydrolase activity
2007-11-08 Added SYNONYM N-formiminoglutamate hydrolase activity
2007-11-08 Added SYNONYM N-formimino-L-glutamate formiminohydrolase activity
2007-09-06 Added SYNONYM formiminoglutamate hydrolase activity
2007-08-09 Deleted SYNONYM formiminoglutamase activity
2007-08-09 Added SYNONYM formiminoglutamase activity
2004-04-19 Added SYNONYM formiminoglutamase activity
2004-04-16 Deleted SYNONYM formiminoglutamase activity
2003-10-27 Added SYNONYM formiminoglutamase activity
2003-08-30 Added DEFINITION Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016813 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines)
Timestamp Action Category Detail
2019-06-20 Deleted XREF KEGG:R02285
2019-06-20 Added XREF KEGG_REACTION:R02285
2018-07-13 Added XREF RHEA:22492
2018-07-13 Deleted XREF RHEA:22495
2010-10-11 Added XREF RHEA:22495
2010-10-11 Added XREF KEGG:R02285
2003-10-27 Added XREF MetaCyc:FORMIMINOGLUTAMASE-RXN
2003-08-30 Added XREF EC:3.5.3.8
Timestamp Action Category Detail
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