This term is obsolete.

GO:0050692 JSON

DNA binding domain binding

Molecular Function

Definition (GO:0050692 GONUTS page)

Binding to a protein's DNA binding domain (DBD). PMID:9682036

203 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
DBD binding exact

Ancestor Chart

Ancestor chart for GO:0050692
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Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I5ZRB2 10116 A0A8I5ZRB2_RAT GO:0050692 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ATU9 10116 A0A8I6ATU9_RAT GO:0050692 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GHJ9 10116 A0A8I6GHJ9_RAT GO:0050692 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B5DFB6 10116 B5DFB6_RAT GO:0050692 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein F1M049 10116 F1M049_RAT GO:0050692 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O70305 10090 ATX2_MOUSE GO:0050692 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9668173
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0050692 based on ALL annotations
The top 100 of 312 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0050692
DNA binding domain binding
985,845.06 100.00 201 201
GO:0061114
branching involved in pancreas morphogenesis
985,845.06 47.76 96 96
GO:2000979
positive regulation of forebrain neuron differentiation
985,845.06 47.76 96 96
GO:0002194
hepatocyte cell migration
985,845.06 47.76 96 96
GO:1901978
positive regulation of cell cycle checkpoint
975,681.70 47.52 96 97
GO:0050693
LBD domain binding
363,801.34 36.35 193 523
GO:0060421
positive regulation of heart growth
482,862.88 31.89 96 196
GO:0060838
lymphatic endothelial cell fate commitment
392,054.25 28.85 103 259
GO:0002157
positive regulation of thyroid hormone receptor signaling pathway
449,504.50 28.76 88 193
GO:0046619
lens placode formation involved in camera-type eye formation
401,021.75 28.15 96 236
Totals 6702 386269
No co-occurrence statistics for GO:0050692 based on MANUAL annotations
The top 100 of 302 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0050692
DNA binding domain binding
88,220.81 100.00 16 16
GO:2000979
positive regulation of forebrain neuron differentiation
70,576.65 23.53 4 5
GO:0050693
LBD domain binding
26,139.50 22.86 8 27
GO:0061114
branching involved in pancreas morphogenesis
66,165.61 17.65 3 4
GO:0002194
hepatocyte cell migration
66,165.61 17.65 3 4
GO:0060838
lymphatic endothelial cell fate commitment
32,080.30 17.39 4 11
GO:1901978
positive regulation of cell cycle checkpoint
52,932.48 16.67 3 5
GO:0046619
lens placode formation involved in camera-type eye formation
27,144.86 16.00 4 13
GO:0070858
negative regulation of bile acid biosynthetic process
27,144.86 16.00 4 13
GO:0055005
ventricular cardiac myofibril assembly
17,644.16 12.50 4 20
Totals 270 4561

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein.
2021-05-24 Added DEFINITION Binding to a protein's DNA binding domain (DBD).
2019-11-01 Added DEFINITION Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein.
2019-11-01 Deleted SYNONYM DNA binding domain binding
2019-11-01 Added SYNONYM DBD binding
2019-11-01 Updated TERM DNA binding domain binding
2019-11-01 Deleted DEFINITION Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
2009-07-03 Deleted DEFINITION Interacting selectively with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
2008-05-13 Added DEFINITION Interacting selectively with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
Timestamp Action Category Detail
2019-11-01 Updated TERM DNA binding domain binding
2003-10-11 Added TERM DBD domain binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein.
2021-05-24 Added DEFINITION Binding to a protein's DNA binding domain (DBD).
2019-11-01 Added DEFINITION Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein.
2019-11-01 Deleted SYNONYM DNA binding domain binding
2019-11-01 Added SYNONYM DBD binding
2019-11-01 Deleted DEFINITION Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
2009-07-03 Deleted DEFINITION Interacting selectively with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
2008-05-13 Added DEFINITION Interacting selectively with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
2008-05-12 Deleted DEFINITION Interacting selectively with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
2007-08-09 Deleted SYNONYM DNA binding domain binding
2007-08-09 Added SYNONYM DNA binding domain binding
2004-04-19 Added SYNONYM DNA binding domain binding
2004-04-16 Deleted SYNONYM DNA binding domain binding
2003-10-11 Added SYNONYM DNA binding domain binding
2003-10-11 Added DEFINITION Interacting selectively with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0019904 (protein domain specific binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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