Note that this term refers to the proliferation of previously activated T cells; it is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells.
GO:0050798
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activated T cell proliferation
Biological Process
Definition (GO:0050798 GONUTS page)
The expansion of a T cell population following activation by an antigenic stimulus.
Comments
Note that this term refers to the proliferation of previously activated T cells; it is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
activated T lymphocyte proliferation | exact |
activated T-cell proliferation | exact |
activated T-lymphocyte proliferation | exact |
proliferation of activated T cells | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0050798
Child Term | Relationship to GO:0050798 |
---|---|
negative regulation of activated T cell proliferation
|
negatively_regulates |
positive regulation of activated T cell proliferation
|
positively_regulates |
regulation of activated T cell proliferation
|
regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0050798 | activated T cell proliferation | Only in Taxon | 7742 | Vertebrata |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5ZNM6 | 10116 | A0A8I5ZNM6_RAT | GO:0050798 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5ZWP3 | 10116 | A0A8I5ZWP3_RAT | GO:0050798 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6I9Y3 | 10116 | A6I9Y3_RAT | GO:0050798 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6J3R4 | 10116 | A6J3R4_RAT | GO:0050798 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | B5LUQ7 | 115422 | FALX3_LITFA | GO:0046651 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332 | |
NOT-qualified manual | protein | B5LUQ8 | 115422 | FALX6_LITFA | GO:0046651 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332 | |
NOT-qualified manual | protein | B5LUQ9 | 115422 | FALX7_LITFA | GO:0046651 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332 | |
NOT-qualified manual | protein | B5LUR0 | 115422 | FALX8_LITFA | GO:0046651 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332 | |
NOT-qualified manual | protein | B5LUR1 | 115422 | FALX9_LITFA | GO:0046651 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332 | |
NOT-qualified manual | protein | D3ZLP3 | 10116 | D3ZLP3_RAT | GO:0050798 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0050798 based on ALL annotations
The top 100 of 655 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
activated T cell proliferation
|
325,984.60 | 100.00 | 598 | 598 |
regulation of CD4-positive, alpha-beta T cell proliferation
|
325,984.60 | 17.56 | 105 | 105 |
protein localization to cytoplasmic microtubule plus-end
|
300,164.03 | 15.35 | 93 | 101 |
DN4 thymocyte differentiation
|
291,505.44 | 15.27 | 93 | 104 |
regulation of T cell homeostatic proliferation
|
173,748.12 | 15.22 | 105 | 197 |
type IV hypersensitivity
|
305,820.56 | 15.07 | 91 | 97 |
negative regulation of dendritic spine maintenance
|
162,992.30 | 13.83 | 96 | 192 |
positive regulation of T cell costimulation
|
147,585.06 | 12.85 | 91 | 201 |
phospholipase C-inhibiting G protein-coupled receptor signaling pathway
|
136,561.12 | 12.79 | 93 | 222 |
regulation of calcium ion import across plasma membrane
|
124,184.60 | 12.73 | 96 | 252 |
Totals | 9219 | 105556 |
No co-occurrence statistics for GO:0050798 based on MANUAL annotations
The top 100 of 561 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
activated T cell proliferation
|
22,272.40 | 100.00 | 58 | 58 |
integrin alphaM-beta2 complex
|
19,652.12 | 25.00 | 15 | 17 |
cellular extravasation
|
12,373.55 | 21.43 | 15 | 27 |
integrin alphaX-beta2 complex
|
18,845.87 | 18.33 | 11 | 13 |
positive regulation of neutrophil degranulation
|
9,651.37 | 17.33 | 13 | 30 |
integrin alphaL-beta2 complex
|
18,560.33 | 16.67 | 10 | 12 |
ICAM-3 receptor activity
|
17,132.61 | 16.39 | 10 | 13 |
positive regulation of mast cell differentiation
|
15,908.85 | 16.13 | 10 | 14 |
vertebrate eye-specific patterning
|
11,878.61 | 12.31 | 8 | 15 |
leukocyte adhesion to vascular endothelial cell
|
11,878.61 | 12.31 | 8 | 15 |
Totals | 701 | 5445 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
2010-10-06 | Added | SYNONYM | proliferation of activated T cells |
2008-05-13 | Added | DEFINITION | The expansion of a T cell population following activation by an antigenic stimulus. |
2008-05-12 | Deleted | DEFINITION | The expansion of a T cell population following activation by an antigenic stimulus. |
2008-04-01 | Updated | RELATION | is a GO:0042098 (T cell proliferation) |
2007-12-27 | Updated | DEFINITION | The expansion of a T cell population following activation by an antigenic stimulus. |
2007-08-09 | Deleted | SYNONYM | activated T-cell proliferation |
2007-08-09 | Deleted | SYNONYM | activated T-lymphocyte proliferation |
2007-08-09 | Deleted | SYNONYM | activated T lymphocyte proliferation |
2007-08-09 | Added | SYNONYM | activated T-cell proliferation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-06-02 | Updated | TERM | activated T cell proliferation |
2004-01-03 | Added | TERM | activated T-cell proliferation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-10-06 | Added | SYNONYM | proliferation of activated T cells |
2008-05-13 | Added | DEFINITION | The expansion of a T cell population following activation by an antigenic stimulus. |
2008-05-12 | Deleted | DEFINITION | The expansion of a T cell population following activation by an antigenic stimulus. |
2007-12-27 | Updated | DEFINITION | The expansion of a T cell population following activation by an antigenic stimulus. |
2007-08-09 | Deleted | SYNONYM | activated T-cell proliferation |
2007-08-09 | Deleted | SYNONYM | activated T-lymphocyte proliferation |
2007-08-09 | Deleted | SYNONYM | activated T lymphocyte proliferation |
2007-08-09 | Added | SYNONYM | activated T-cell proliferation |
2007-08-09 | Added | SYNONYM | activated T lymphocyte proliferation |
2007-08-09 | Added | SYNONYM | activated T-lymphocyte proliferation |
2005-06-02 | Added | SYNONYM | activated T lymphocyte proliferation |
2005-06-02 | Added | SYNONYM | activated T-cell proliferation |
2005-06-02 | Added | SYNONYM | activated T-lymphocyte proliferation |
2005-05-26 | Updated | DEFINITION | The rapid expansion of a T cell population following activation by an antigenic stimulus. |
2004-01-03 | Added | DEFINITION | The rapid expansion of a T-cell population following activation by an antigenic stimulus. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0042098 (T cell proliferation) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
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