This term is obsolete.
Note that this term refers to the proliferation of previously activated T cells; it is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells.

GO:0050798 JSON

activated T cell proliferation

Biological Process

Definition (GO:0050798 GONUTS page)

The expansion of a T cell population following activation by an antigenic stimulus.

Comments

Note that this term refers to the proliferation of previously activated T cells; it is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells.

609 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
activated T lymphocyte proliferation exact
activated T-cell proliferation exact
activated T-lymphocyte proliferation exact
proliferation of activated T cells exact

Ancestor Chart

Ancestor chart for GO:0050798
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0050798

Child Term Relationship to
GO:0050798
negative regulation of activated T cell proliferation
negatively_regulates
positive regulation of activated T cell proliferation
positively_regulates
regulation of activated T cell proliferation
regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0050798 activated T cell proliferation Only in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I5ZNM6 10116 A0A8I5ZNM6_RAT GO:0050798 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZWP3 10116 A0A8I5ZWP3_RAT GO:0050798 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6I9Y3 10116 A6I9Y3_RAT GO:0050798 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6J3R4 10116 A6J3R4_RAT GO:0050798 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B5LUQ7 115422 FALX3_LITFA GO:0046651 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332
NOT-qualified manual protein B5LUQ8 115422 FALX6_LITFA GO:0046651 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332
NOT-qualified manual protein B5LUQ9 115422 FALX7_LITFA GO:0046651 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332
NOT-qualified manual protein B5LUR0 115422 FALX8_LITFA GO:0046651 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332
NOT-qualified manual protein B5LUR1 115422 FALX9_LITFA GO:0046651 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18803332
NOT-qualified manual protein D3ZLP3 10116 D3ZLP3_RAT GO:0050798 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0050798 based on ALL annotations
The top 100 of 655 co-occurring terms
Co-occurring Term PR S% #Together #Compared
activated T cell proliferation
325,984.60 100.00 598 598
regulation of CD4-positive, alpha-beta T cell proliferation
325,984.60 17.56 105 105
protein localization to cytoplasmic microtubule plus-end
300,164.03 15.35 93 101
DN4 thymocyte differentiation
291,505.44 15.27 93 104
regulation of T cell homeostatic proliferation
173,748.12 15.22 105 197
type IV hypersensitivity
305,820.56 15.07 91 97
negative regulation of dendritic spine maintenance
162,992.30 13.83 96 192
positive regulation of T cell costimulation
147,585.06 12.85 91 201
phospholipase C-inhibiting G protein-coupled receptor signaling pathway
136,561.12 12.79 93 222
regulation of calcium ion import across plasma membrane
124,184.60 12.73 96 252
Totals 9219 105556
No co-occurrence statistics for GO:0050798 based on MANUAL annotations
The top 100 of 561 co-occurring terms
Co-occurring Term PR S% #Together #Compared
activated T cell proliferation
22,272.40 100.00 58 58
integrin alphaM-beta2 complex
19,652.12 25.00 15 17
cellular extravasation
12,373.55 21.43 15 27
integrin alphaX-beta2 complex
18,845.87 18.33 11 13
positive regulation of neutrophil degranulation
9,651.37 17.33 13 30
integrin alphaL-beta2 complex
18,560.33 16.67 10 12
ICAM-3 receptor activity
17,132.61 16.39 10 13
positive regulation of mast cell differentiation
15,908.85 16.13 10 14
vertebrate eye-specific patterning
11,878.61 12.31 8 15
leukocyte adhesion to vascular endothelial cell
11,878.61 12.31 8 15
Totals 701 5445

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2010-10-06 Added SYNONYM proliferation of activated T cells
2008-05-13 Added DEFINITION The expansion of a T cell population following activation by an antigenic stimulus.
2008-05-12 Deleted DEFINITION The expansion of a T cell population following activation by an antigenic stimulus.
2008-04-01 Updated RELATION is a GO:0042098 (T cell proliferation)
2007-12-27 Updated DEFINITION The expansion of a T cell population following activation by an antigenic stimulus.
2007-08-09 Deleted SYNONYM activated T-cell proliferation
2007-08-09 Deleted SYNONYM activated T-lymphocyte proliferation
2007-08-09 Deleted SYNONYM activated T lymphocyte proliferation
2007-08-09 Added SYNONYM activated T-cell proliferation
Timestamp Action Category Detail
2005-06-02 Updated TERM activated T cell proliferation
2004-01-03 Added TERM activated T-cell proliferation
Timestamp Action Category Detail
2010-10-06 Added SYNONYM proliferation of activated T cells
2008-05-13 Added DEFINITION The expansion of a T cell population following activation by an antigenic stimulus.
2008-05-12 Deleted DEFINITION The expansion of a T cell population following activation by an antigenic stimulus.
2007-12-27 Updated DEFINITION The expansion of a T cell population following activation by an antigenic stimulus.
2007-08-09 Deleted SYNONYM activated T-cell proliferation
2007-08-09 Deleted SYNONYM activated T-lymphocyte proliferation
2007-08-09 Deleted SYNONYM activated T lymphocyte proliferation
2007-08-09 Added SYNONYM activated T-cell proliferation
2007-08-09 Added SYNONYM activated T lymphocyte proliferation
2007-08-09 Added SYNONYM activated T-lymphocyte proliferation
2005-06-02 Added SYNONYM activated T lymphocyte proliferation
2005-06-02 Added SYNONYM activated T-cell proliferation
2005-06-02 Added SYNONYM activated T-lymphocyte proliferation
2005-05-26 Updated DEFINITION The rapid expansion of a T cell population following activation by an antigenic stimulus.
2004-01-03 Added DEFINITION The rapid expansion of a T-cell population following activation by an antigenic stimulus.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0042098 (T cell proliferation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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