This term is obsolete.

GO:0051145 JSON

smooth muscle cell differentiation

Biological Process

Definition (GO:0051145 GONUTS page)

The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.

8,704 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
nonstriated muscle cell differentiation exact

Ancestor Chart

Ancestor chart for GO:0051145
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0051145

Child Term Relationship to
GO:0051145
vascular associated smooth muscle cell differentiation
is_a
enteric smooth muscle cell differentiation
is_a
regulation of smooth muscle cell differentiation
regulates
kidney smooth muscle cell differentiation
is_a
ureter smooth muscle cell differentiation
is_a
smooth muscle cell differentiation involved in prostate glandular acinus development
is_a
negative regulation of smooth muscle cell differentiation
negatively_regulates
positive regulation of smooth muscle cell differentiation
positively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0051145 smooth muscle cell differentiation Only in Taxon 6072 Eumetazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q8VDV3-1 10090 R3GEF_MOUSE GO:0042692 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:28096466

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0000192 smooth muscle cell

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:2000721 obsolete positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation consider GO:0051145
GO:2000745 obsolete positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation consider GO:0051145
GO:2000820 obsolete negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation consider GO:0051145

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0051145 based on ALL annotations
The top 100 of 1,127 co-occurring terms
Co-occurring Term PR S% #Together #Compared
smooth muscle cell differentiation
29,711.75 100.00 6,561 6,561
cardiac muscle cell differentiation
11,993.40 15.55 1,324 3,280
lymph vessel development
7,934.31 7.00 568 2,127
regulation of vascular endothelial growth factor receptor signaling pathway
5,370.46 5.86 524 2,899
epithelial tube branching involved in lung morphogenesis
7,796.70 5.69 444 1,692
endocardial cushion formation
8,826.92 3.69 265 892
branching involved in ureteric bud morphogenesis
3,015.73 3.64 352 3,468
mesonephros development
7,175.56 3.56 263 1,089
metanephros development
3,319.57 3.38 303 2,712
outflow tract morphogenesis
2,421.67 3.35 353 4,331
Totals 33451 405570
No co-occurrence statistics for GO:0051145 based on MANUAL annotations
The top 100 of 1,059 co-occurring terms
Co-occurring Term PR S% #Together #Compared
smooth muscle cell differentiation
9,640.29 100.00 134 134
cardiac muscle cell differentiation
1,285.37 7.94 22 165
regulation of vascular endothelial growth factor receptor signaling pathway
1,483.12 6.64 14 91
leucine zipper domain binding
2,466.12 6.63 11 43
lymph vessel development
1,291.11 6.49 15 112
muscle cell fate determination
4,820.15 6.29 9 18
positive regulation of osteoblast differentiation
765.10 5.90 25 315
regulation of modification of postsynaptic structure
1,928.06 5.75 10 50
epithelial tube branching involved in lung morphogenesis
1,285.37 5.66 12 90
smooth muscle contractile fiber
4,820.15 5.63 8 16
Totals 885 7668

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2010-03-11 Deleted RELATION part of GO:0048745 (smooth muscle tissue development)
2010-03-03 Added RELATION part of GO:0048745 (smooth muscle tissue development)
2008-05-13 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2008-05-12 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2008-04-01 Updated RELATION is a GO:0042692 (muscle cell differentiation)
2007-08-09 Deleted SYNONYM nonstriated muscle cell differentiation
2007-08-09 Added SYNONYM nonstriated muscle cell differentiation
Timestamp Action Category Detail
2004-09-25 Added TERM smooth muscle cell differentiation
Timestamp Action Category Detail
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2008-05-13 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2008-05-12 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2007-08-09 Deleted SYNONYM nonstriated muscle cell differentiation
2007-08-09 Added SYNONYM nonstriated muscle cell differentiation
2005-06-30 Updated DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2005-01-21 Updated DEFINITION Processes whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
2004-09-25 Added SYNONYM nonstriated muscle cell differentiation
2004-09-25 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
Timestamp Action Category Detail
2010-03-11 Deleted RELATION part of GO:0048745 (smooth muscle tissue development)
2010-03-03 Added RELATION part of GO:0048745 (smooth muscle tissue development)
2008-04-01 Updated RELATION is a GO:0042692 (muscle cell differentiation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
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