GO:0051380
JSON
norepinephrine binding
Molecular Function
Definition (GO:0051380 GONUTS page)
Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
noradrenaline binding | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:72587 | (R)-noradrenaline(1+) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0051380 based on ALL annotations
The top 100 of 252 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
norepinephrine binding
|
134,255.36 | 100.00 | 1,452 | 1,452 |
beta2-adrenergic receptor activity
|
122,527.31 | 76.05 | 1,191 | 1,305 |
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
|
66,480.48 | 46.50 | 1,284 | 2,593 |
regulation of smooth muscle contraction
|
19,501.54 | 13.19 | 856 | 5,893 |
adrenergic receptor activity
|
19,588.16 | 10.51 | 397 | 2,721 |
heat generation
|
63,088.48 | 10.02 | 164 | 349 |
diet induced thermogenesis
|
28,894.85 | 8.00 | 164 | 762 |
blood vessel diameter maintenance
|
11,117.94 | 7.75 | 794 | 9,588 |
fear response
|
31,319.29 | 7.71 | 150 | 643 |
negative regulation of multicellular organism growth
|
19,297.00 | 6.75 | 164 | 1,141 |
Totals | 21444 | 3094977 |
No co-occurrence statistics for GO:0051380 based on MANUAL annotations
The top 100 of 229 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
norepinephrine binding
|
26,363.25 | 100.00 | 49 | 49 |
beta2-adrenergic receptor activity
|
23,261.69 | 56.60 | 30 | 34 |
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
|
12,357.77 | 36.14 | 30 | 64 |
beta-adrenergic receptor activity
|
24,605.70 | 28.00 | 14 | 15 |
beta3-adrenergic receptor activity
|
12,727.09 | 21.88 | 14 | 29 |
positive regulation of lipophagy
|
9,090.77 | 14.71 | 10 | 29 |
negative regulation of G protein-coupled receptor signaling pathway
|
5,478.08 | 14.55 | 16 | 77 |
epinephrine binding
|
3,721.87 | 9.84 | 12 | 85 |
adenylate cyclase-activating adrenergic receptor signaling pathway
|
2,080.12 | 7.85 | 46 | 583 |
positive regulation of autophagosome maturation
|
2,929.25 | 7.75 | 10 | 90 |
Totals | 481 | 11930 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-04 | Added | RELATION | is a GO:0043169 (cation binding) |
2021-05-24 | Added | DEFINITION | Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2012-10-29 | Deleted | RELATION | is a GO:0043176 (amine binding) |
2012-10-04 | Deleted | RELATION | is a GO:0043178 (alcohol binding) |
2012-09-07 | Added | RELATION | is a GO:1901338 (catecholamine binding) |
2009-07-06 | Added | RELATION | is a GO:0043178 (alcohol binding) |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2008-10-02 | Deleted | RELATION | is a GO:0042562 (hormone binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-06-27 | Added | TERM | norepinephrine binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2008-05-13 | Added | DEFINITION | Interacting selectively with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2007-08-09 | Added | SYNONYM | noradrenaline binding |
2007-08-09 | Deleted | SYNONYM | noradrenaline binding |
2005-06-27 | Added | DEFINITION | Interacting selectively with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. |
2005-06-27 | Added | SYNONYM | noradrenaline binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-04 | Added | RELATION | is a GO:0043169 (cation binding) |
2012-10-29 | Deleted | RELATION | is a GO:0043176 (amine binding) |
2012-10-04 | Deleted | RELATION | is a GO:0043178 (alcohol binding) |
2012-09-07 | Added | RELATION | is a GO:1901338 (catecholamine binding) |
2009-07-06 | Added | RELATION | is a GO:0043178 (alcohol binding) |
2008-10-02 | Deleted | RELATION | is a GO:0042562 (hormone binding) |
2008-10-02 | Deleted | RELATION | is a GO:0042165 (obsolete neurotransmitter binding) |
2008-04-01 | Updated | RELATION | is a GO:0042165 (obsolete neurotransmitter binding) |
2008-04-01 | Updated | RELATION | is a GO:0042562 (hormone binding) |
2008-04-01 | Updated | RELATION | is a GO:0043176 (amine binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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