GO:0051595
JSON
response to methylglyoxal
Biological Process
Definition (GO:0051595 GONUTS page)
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| response to pyruvaldehyde | exact |
Ancestor Chart
Ancestor chart for GO:0051595
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0051595
| Child Term | Relationship to GO:0051595 |
|---|---|
|
cellular response to methylglyoxal
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Response to guidelines | Link |
Cross-references
| Database | ID | Description |
|---|---|---|
| InterPro | IPR023941 | Glutathione-regulated potassium-efflux system protein KefC |
Cross-Ontology Relations
| Relation | Other Ontology | ID | Term |
|---|---|---|---|
| has_primary_input | CHEBI | CHEBI:17158 | methylglyoxal |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0051595 based on ALL annotations
The top 100 of 191 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
response to methylglyoxal
|
147,436.66 | 100.00 | 1,344 | 1,344 |
|
glutathione-regulated potassium exporter activity
|
62,468.04 | 40.93 | 1,241 | 2,929 |
|
toxic substance binding
|
15,411.80 | 10.36 | 1,241 | 11,872 |
|
regulation of axon extension
|
15,616.87 | 4.37 | 93 | 878 |
|
cerebral cortex neuron differentiation
|
12,672.47 | 3.99 | 93 | 1,082 |
|
negative regulation of protein localization to nucleus
|
8,479.66 | 3.24 | 93 | 1,617 |
|
negative regulation of circadian rhythm
|
7,175.10 | 2.94 | 93 | 1,911 |
|
enzyme binding
|
4,122.04 | 2.79 | 1,241 | 44,388 |
|
type I interferon-mediated signaling pathway
|
4,137.48 | 2.04 | 93 | 3,314 |
|
positive regulation of defense response to virus by host
|
4,075.98 | 2.02 | 93 | 3,364 |
| Totals | 12536 | 6199103 | ||
No co-occurrence statistics for GO:0051595 based on MANUAL annotations
The top 100 of 172 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
response to methylglyoxal
|
128,321.19 | 100.00 | 11 | 11 |
|
cellular response to tert-butyl hydroperoxide
|
128,321.19 | 18.18 | 2 | 2 |
|
regulation of CD4-positive, alpha-beta T cell activation
|
64,160.59 | 8.33 | 1 | 2 |
|
high mobility group box 1 binding
|
64,160.59 | 8.33 | 1 | 2 |
|
response to selenite ion
|
64,160.59 | 8.33 | 1 | 2 |
|
glutathione-regulated potassium exporter activity
|
42,773.73 | 7.69 | 1 | 3 |
|
regulation of hormone levels
|
12,832.12 | 6.90 | 2 | 20 |
|
negative regulation of blood circulation
|
25,664.24 | 6.67 | 1 | 5 |
|
positive regulation of DNA-templated DNA replication
|
16,040.15 | 5.56 | 1 | 8 |
|
cellular detoxification of methylglyoxal
|
14,257.91 | 5.26 | 1 | 9 |
| Totals | 141 | 14992 | ||
Change Log
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- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2015-06-25 | Deleted | RELATION | is a GO:0010033 (obsolete response to organic substance) |
| 2015-06-25 | Deleted | RELATION | is a GO:1901700 (response to oxygen-containing compound) |
| 2014-11-13 | Added | RELATION | is a GO:1901654 (response to ketone) |
| 2013-06-13 | Deleted | RELATION | is a GO:0009636 (response to toxic substance) |
| 2012-12-15 | Added | RELATION | is a GO:1901700 (response to oxygen-containing compound) |
| 2012-02-04 | Deleted | DEFINITION | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. |
| 2012-02-04 | Added | RELATION | is a GO:0010033 (obsolete response to organic substance) |
| 2012-02-04 | Added | DEFINITION | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal. |
| 2011-05-08 | Added | DEFINITION | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. |
| 2011-05-08 | Deleted | DEFINITION | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2005-09-18 | Added | TERM | response to methylglyoxal |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2012-02-04 | Deleted | DEFINITION | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. |
| 2012-02-04 | Added | DEFINITION | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal. |
| 2011-05-08 | Added | DEFINITION | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. |
| 2011-05-08 | Deleted | DEFINITION | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. |
| 2008-05-13 | Added | DEFINITION | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. |
| 2008-05-12 | Deleted | DEFINITION | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. |
| 2007-08-09 | Deleted | SYNONYM | response to pyruvaldehyde |
| 2007-08-09 | Added | SYNONYM | response to pyruvaldehyde |
| 2005-09-20 | Updated | DEFINITION | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. |
| 2005-09-18 | Added | SYNONYM | response to pyruvaldehyde |
| 2005-09-18 | Added | DEFINITION | A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perception of, or exposure to, methylglyoxal. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2015-06-25 | Deleted | RELATION | is a GO:0010033 (obsolete response to organic substance) |
| 2015-06-25 | Deleted | RELATION | is a GO:1901700 (response to oxygen-containing compound) |
| 2014-11-13 | Added | RELATION | is a GO:1901654 (response to ketone) |
| 2013-06-13 | Deleted | RELATION | is a GO:0009636 (response to toxic substance) |
| 2012-12-15 | Added | RELATION | is a GO:1901700 (response to oxygen-containing compound) |
| 2012-02-04 | Added | RELATION | is a GO:0010033 (obsolete response to organic substance) |
| 2008-04-01 | Updated | RELATION | is a GO:0009636 (response to toxic substance) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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