This term is obsolete.

GO:0051717 JSON

inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity

Molecular Function

Definition (GO:0051717 GONUTS page)

Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate.

1,215 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity related
inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity related
inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity related

Ancestor Chart

Ancestor chart for GO:0051717
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0051717

Child Term Relationship to
GO:0051717
PTEN phosphatase complex
capable_of

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein A0A087QTQ7 9233 A0A087QTQ7_APTFO GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A087VMI5 100784 A0A087VMI5_BALRE GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091CMN8 885580 A0A091CMN8_FUKDA GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091HHI2 9244 A0A091HHI2_CALAN GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091JLW6 188379 A0A091JLW6_EGRGA GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091L9X5 187382 A0A091L9X5_9AVES GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091P439 57397 A0A091P439_APAVI GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091SAD7 54374 A0A091SAD7_9AVES GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091SQ34 176057 A0A091SQ34_NESNO GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A093DPA0 121530 A0A093DPA0_TAUER GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130

Cross-references

Database ID Description
InterPro IPR017361 Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN
MetaCyc 3.1.3.62-RXN
RHEA 77155
Reactome R-HSA-1855200
Reactome R-HSA-1855205

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:43474 hydrogenphosphate
has_participant CHEBI CHEBI:203600 1D-myo-inositol 1,4,5-trisphosphate(6-)
has_participant CHEBI CHEBI:57895 1D-myo-inositol 1,3,4,5-tetrakisphosphate(8-)
has_participant CHEBI CHEBI:15377 water

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0051717 based on ALL annotations
The top 100 of 280 co-occurring terms
Co-occurring Term PR S% #Together #Compared
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
161,239.69 100.00 1,209 1,209
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
160,839.58 99.50 1,206 1,209
phosphatidylinositol phosphate phosphatase activity
27,717.23 17.02 1,144 6,655
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
26,454.81 16.29 1,159 7,064
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
24,965.34 15.48 1,206 7,789
cell motility
11,038.86 6.83 1,159 16,929
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
70,414.81 5.32 69 158
negative regulation of keratinocyte migration
154,020.00 5.28 64 67
phosphatidylinositol 3-kinase/protein kinase B signal transduction
8,285.92 5.13 1,160 22,573
negative regulation of wound healing, spreading of epidermal cells
45,660.80 4.67 64 226
Totals 31516 4721720
No co-occurrence statistics for GO:0051717 based on MANUAL annotations
The top 100 of 210 co-occurring terms
Co-occurring Term PR S% #Together #Compared
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
143,533.22 100.00 9 9
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
107,649.91 54.55 6 8
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
91,339.32 53.85 7 11
negative regulation of synaptic vesicle clustering
143,533.23 33.33 3 3
regulation of macrophage apoptotic process
143,533.22 22.22 2 2
regulation of cellular component size
71,766.61 18.18 2 4
rhythmic synaptic transmission
39,145.43 17.65 3 11
negative regulation of keratinocyte migration
57,413.29 16.67 2 5
regulation of B cell apoptotic process
57,413.29 16.67 2 5
inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
57,413.29 16.67 2 5
Totals 241 8127

Change Log

Timestamp Action Category Detail
2024-06-20 Added XREF RHEA:77155
2024-06-20 Deleted DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
2024-06-20 Added DEFINITION Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate.
2020-10-08 Deleted SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2020-10-08 Deleted SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2020-10-08 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2020-10-08 Deleted SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2020-10-08 Added SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2020-10-08 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2019-04-01 Deleted XREF reactome:R-HSA-1855200
Timestamp Action Category Detail
2005-12-16 Added TERM inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
Timestamp Action Category Detail
2024-06-20 Deleted DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
2024-06-20 Added DEFINITION Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate.
2020-10-08 Deleted SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2020-10-08 Deleted SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2020-10-08 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2020-10-08 Deleted SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2020-10-08 Added SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2020-10-08 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
2007-09-06 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2007-09-06 Added SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2007-09-06 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2005-12-16 Added DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
Timestamp Action Category Detail
2011-09-16 Added RELATION is a GO:0052743 (inositol tetrakisphosphate phosphatase activity)
2011-09-16 Deleted RELATION is a GO:0004437 (obsolete inositol or phosphatidylinositol phosphatase activity)
2008-04-01 Updated RELATION is a GO:0004437 (obsolete inositol or phosphatidylinositol phosphatase activity)
Timestamp Action Category Detail
2024-06-20 Added XREF RHEA:77155
2019-04-01 Deleted XREF reactome:R-HSA-1855200
2019-04-01 Added XREF Reactome:R-HSA-1855205
2019-04-01 Added XREF Reactome:R-HSA-1855200
2019-04-01 Deleted XREF reactome:R-HSA-1855205
2018-12-11 Added XREF reactome:R-HSA-1855205
2018-12-11 Added XREF reactome:R-HSA-1855200
2005-12-16 Added XREF MetaCyc:3.1.3.62-RXN
Timestamp Action Category Detail
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