This term is obsolete.

GO:0051717 JSON

inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity

Molecular Function

Definition (GO:0051717 GONUTS page)

Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate.

1,247 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity related
inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity related
inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity related

Ancestor Chart

Ancestor chart for GO:0051717
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0051717

Child Term Relationship to
GO:0051717
GO:1990455
PTEN phosphatase complex
capable_of

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein A0A087QTQ7 9233 A0A087QTQ7_APTFO GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A087VMI5 100784 A0A087VMI5_BALRE GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091CMN8 885580 A0A091CMN8_FUKDA GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091HHI2 9244 A0A091HHI2_CALAN GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091JLW6 188379 A0A091JLW6_EGRGA GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091L9X5 187382 A0A091L9X5_9AVES GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091P439 57397 A0A091P439_APAVI GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091SAD7 54374 A0A091SAD7_9AVES GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A091SQ34 176057 A0A091SQ34_NESNO GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130
IEA Review protein A0A093DPA0 121530 A0A093DPA0_TAUER GO:0016791 To remove over-annotation from InterPro entries. These proteins share homology with protein tyrosine phosphatases but do not have enzyme activity. Therefore, they cannot be annotated to phosphatase activity or related GO terms. Reported by InterPro on the 15th of April, 2016. IPR000387|IPR016130

Cross-references

Database ID Description
InterPro IPR017361 Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN
MetaCyc 3.1.3.62-RXN
RHEA 77155
Reactome R-HSA-1855200
Reactome R-HSA-1855205

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:43474 hydrogenphosphate
has_participant CHEBI CHEBI:203600 1D-myo-inositol 1,4,5-trisphosphate(6-)
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:57895 1D-myo-inositol 1,3,4,5-tetrakisphosphate(8-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0051717 based on ALL annotations
The top 100 of 287 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0051717
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
159,673.55 100.00 1,241 1,241
GO:0051800
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
159,283.78 98.55 1,226 1,229
GO:0052866
phosphatidylinositol phosphate phosphatase activity
27,232.41 16.88 1,171 6,866
GO:0051896
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
26,379.11 16.40 1,188 7,191
GO:0016314
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
24,272.57 15.20 1,238 8,144
GO:0048870
cell motility
10,882.87 6.79 1,186 17,401
GO:0050793
regulation of developmental process
10,388.56 6.50 1,232 18,936
GO:0030351
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
69,730.85 5.19 69 158
GO:0043491
phosphatidylinositol 3-kinase/protein kinase B signal transduction
8,242.69 5.15 1,187 22,994
GO:0051548
negative regulation of keratinocyte migration
152,523.98 5.14 64 67
Totals 33166 4929942
No co-occurrence statistics for GO:0051717 based on MANUAL annotations
The top 100 of 211 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0051717
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
156,837.00 100.00 9 9
GO:0051800
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
117,627.76 54.55 6 8
GO:0030351
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
99,805.37 53.85 7 11
GO:2000808
negative regulation of synaptic vesicle clustering
156,837.00 33.33 3 3
GO:2000109
regulation of macrophage apoptotic process
156,837.00 22.22 2 2
GO:0032535
regulation of cellular component size
78,418.50 18.18 2 4
GO:0060024
rhythmic synaptic transmission
42,773.73 17.65 3 11
GO:0051548
negative regulation of keratinocyte migration
62,734.80 16.67 2 5
GO:0002902
regulation of B cell apoptotic process
62,734.80 16.67 2 5
GO:0030352
inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
62,734.80 16.67 2 5
Totals 242 8241

Change Log

Timestamp Action Category Detail
2024-06-20 Deleted DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
2024-06-20 Added XREF RHEA:77155
2024-06-20 Added DEFINITION Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate.
2020-10-08 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2020-10-08 Deleted SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2020-10-08 Added SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2020-10-08 Deleted SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2020-10-08 Deleted SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2020-10-08 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2019-04-01 Deleted XREF reactome:R-HSA-1855205
Timestamp Action Category Detail
2005-12-16 Added TERM inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
Timestamp Action Category Detail
2024-06-20 Deleted DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
2024-06-20 Added DEFINITION Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate.
2020-10-08 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2020-10-08 Deleted SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2020-10-08 Added SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2020-10-08 Deleted SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2020-10-08 Deleted SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2020-10-08 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
2007-09-06 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity
2007-09-06 Added SYNONYM inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity
2007-09-06 Added SYNONYM inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity
2005-12-16 Added DEFINITION Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
Timestamp Action Category Detail
2011-09-16 Deleted RELATION is a GO:0004437 (obsolete inositol or phosphatidylinositol phosphatase activity)
2011-09-16 Added RELATION is a GO:0052743 (inositol tetrakisphosphate phosphatase activity)
2008-04-01 Updated RELATION is a GO:0004437 (obsolete inositol or phosphatidylinositol phosphatase activity)
Timestamp Action Category Detail
2024-06-20 Added XREF RHEA:77155
2019-04-01 Deleted XREF reactome:R-HSA-1855205
2019-04-01 Added XREF Reactome:R-HSA-1855200
2019-04-01 Deleted XREF reactome:R-HSA-1855200
2019-04-01 Added XREF Reactome:R-HSA-1855205
2018-12-11 Added XREF reactome:R-HSA-1855200
2018-12-11 Added XREF reactome:R-HSA-1855205
2005-12-16 Added XREF MetaCyc:3.1.3.62-RXN
Timestamp Action Category Detail
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