This term is obsolete.

GO:0052734 JSON

shikimate 3-dehydrogenase (NAD+) activity

Molecular Function

Definition (GO:0052734 GONUTS page)

Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+.

644 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
3-dehydroshikimic reductase activity related
shikimate:NAD(P)(+) oxidoreductase activity broad
shikimate oxidoreductase activity broad
shikimate:NAD(P)(+) 3-oxidoreductase activity related
dehydroshikimic reductase activity broad
3-dehydroshikimate reductase activity related
DHS reductase activity broad

Ancestor Chart

Ancestor chart for GO:0052734
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4KZV0 6945 A0A1S4KZV0_IXOSC GO:0016616 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
EC 1.1.1.282
InterPro IPR022872 Quinate/Shikimate dehydrogenase
KEGG_REACTION R06847
RHEA 17741

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:57945 NADH(2-)
has_participant CHEBI CHEBI:57540 NAD(1-)
has_participant CHEBI CHEBI:36208 shikimate
has_participant CHEBI CHEBI:16630 3-dehydroshikimate

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0033706 obsolete quinate/shikimate dehydrogenase activity consider GO:0052734

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0052734 based on ALL annotations
The top 16 of 16 co-occurring terms
Co-occurring Term PR S% #Together #Compared
shikimate 3-dehydrogenase (NAD+) activity
303,170.72 100.00 643 643
quinate 3-dehydrogenase (NADP+) activity
303,170.75 99.53 640 640
quinate 3-dehydrogenase (NAD+) activity
296,259.56 97.72 643 658
shikimate metabolic process
3,159.61 1.04 625 59,970
shikimate 3-dehydrogenase (NADP+) activity
3,071.50 1.01 643 63,467
chorismate biosynthetic process
631.14 0.21 625 300,220
aromatic amino acid family biosynthetic process
477.17 0.16 588 373,587
amino acid biosynthetic process
228.99 0.08 588 778,477
NADP binding
30.76 0.01 88 867,427
oxidoreductase activity
16.37 0.01 643 11,906,003
Totals 5825 104995854
No co-occurrence statistics for GO:0052734 based on MANUAL annotations
The top 7 of 7 co-occurring terms
Co-occurring Term PR S% #Together #Compared
shikimate 3-dehydrogenase (NAD+) activity
1,291,799.00 100.00 1 1
quinate 3-dehydrogenase (NAD+) activity
258,359.80 20.00 1 5
shikimate 3-dehydrogenase (NADP+) activity
6,728.12 0.52 1 192
shikimate metabolic process
6,557.36 0.51 1 197
chorismate biosynthetic process
2,896.41 0.22 1 446
protein homodimerization activity
242.87 0.02 1 5,319
protein binding
30.89 0.00 1 41,817
Totals 7 47977

Change Log

Timestamp Action Category Detail
2020-10-08 Added SYNONYM 3-dehydroshikimate reductase activity
2020-10-08 Added SYNONYM shikimate:NAD(P)(+) 3-oxidoreductase activity
2020-10-08 Added SYNONYM 3-dehydroshikimic reductase activity
2020-10-08 Deleted SYNONYM 3-dehydroshikimate reductase activity
2020-10-08 Deleted SYNONYM shikimate:NAD(P)(+) 3-oxidoreductase activity
2020-10-08 Deleted SYNONYM 3-dehydroshikimic reductase activity
2019-06-20 Added XREF KEGG_REACTION:R06847
2019-06-20 Deleted XREF KEGG:R06847
2018-07-13 Added XREF RHEA:17741
2018-07-13 Deleted XREF RHEA:17744
Timestamp Action Category Detail
2011-08-19 Added TERM shikimate 3-dehydrogenase (NAD+) activity
Timestamp Action Category Detail
2020-10-08 Added SYNONYM 3-dehydroshikimate reductase activity
2020-10-08 Added SYNONYM shikimate:NAD(P)(+) 3-oxidoreductase activity
2020-10-08 Added SYNONYM 3-dehydroshikimic reductase activity
2020-10-08 Deleted SYNONYM 3-dehydroshikimate reductase activity
2020-10-08 Deleted SYNONYM shikimate:NAD(P)(+) 3-oxidoreductase activity
2020-10-08 Deleted SYNONYM 3-dehydroshikimic reductase activity
2011-08-19 Added SYNONYM shikimate:NAD(P)(+) oxidoreductase activity
2011-08-19 Added SYNONYM shikimate oxidoreductase activity
2011-08-19 Added SYNONYM 3-dehydroshikimic reductase activity
2011-08-19 Added SYNONYM DHS reductase activity
2011-08-19 Added DEFINITION Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+.
2011-08-19 Added SYNONYM 3-dehydroshikimate reductase activity
2011-08-19 Added SYNONYM shikimate:NAD(P)(+) 3-oxidoreductase activity
2011-08-19 Added SYNONYM dehydroshikimic reductase activity
Timestamp Action Category Detail
2011-08-19 Added RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Timestamp Action Category Detail
2019-06-20 Added XREF KEGG_REACTION:R06847
2019-06-20 Deleted XREF KEGG:R06847
2018-07-13 Added XREF RHEA:17741
2018-07-13 Deleted XREF RHEA:17744
2011-08-19 Added XREF RHEA:17744
2011-08-19 Added XREF EC:1.1.1.282
2011-08-19 Added XREF KEGG:R06847
Timestamp Action Category Detail
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