GO:0060008
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Sertoli cell differentiation
Biological Process
Definition (GO:0060008 GONUTS page)
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0060008
Child Term | Relationship to GO:0060008 |
---|---|
Sertoli cell fate commitment
|
part_of |
Sertoli cell development
|
part_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0060008 | Sertoli cell differentiation | Only in Taxon | 6072 | Eumetazoa |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
results_in_acquisition_of_features_of | CL | CL:0000216 | Sertoli cell |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0060008 based on ALL annotations
The top 100 of 551 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Sertoli cell differentiation
|
327,078.50 | 100.00 | 596 | 596 |
positive regulation of male gonad development
|
152,934.31 | 30.18 | 274 | 586 |
renal vesicle induction
|
215,922.92 | 24.74 | 169 | 256 |
male sex determination
|
76,578.79 | 19.97 | 343 | 1,465 |
Sertoli cell development
|
92,446.98 | 16.60 | 171 | 605 |
negative regulation of immune system process
|
320,192.62 | 15.55 | 93 | 95 |
enzyme activator complex
|
277,708.16 | 14.71 | 90 | 106 |
cell proliferation involved in heart morphogenesis
|
327,078.53 | 14.60 | 87 | 87 |
regulation of branching involved in lung morphogenesis
|
327,078.53 | 14.60 | 87 | 87 |
regulation of epithelial cell proliferation involved in lung morphogenesis
|
327,078.53 | 14.60 | 87 | 87 |
Totals | 10159 | 41929 |
No co-occurrence statistics for GO:0060008 based on MANUAL annotations
The top 100 of 506 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Sertoli cell differentiation
|
26,912.48 | 100.00 | 48 | 48 |
renal vesicle induction
|
19,735.82 | 21.15 | 11 | 15 |
heart valve morphogenesis
|
10,092.18 | 20.55 | 15 | 40 |
epithelial cell proliferation involved in prostatic bud elongation
|
26,912.48 | 18.75 | 9 | 9 |
regulation of cell proliferation involved in tissue homeostasis
|
22,019.30 | 18.00 | 9 | 11 |
negative regulation of immune system process
|
22,019.30 | 18.00 | 9 | 11 |
positive regulation of male gonad development
|
7,849.47 | 17.07 | 14 | 48 |
morphogenesis of a branching epithelium
|
15,138.27 | 16.36 | 9 | 16 |
positive regulation of mesenchymal stem cell differentiation
|
15,138.27 | 16.36 | 9 | 16 |
positive regulation of kidney development
|
14,247.78 | 16.07 | 9 | 17 |
Totals | 736 | 5242 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-22 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
2024-03-22 | Deleted | CONSTRAINT | in_taxon NCBITaxon:33213 (Bilateria) |
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33213 (Bilateria) |
2017-08-13 | Deleted | RELATION | is a GO:0044702 (single organism reproductive process) |
2016-08-06 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2016-06-22 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2014-07-30 | Deleted | RELATION | is a GO:0048610 (obsolete cellular process involved in reproduction) |
2013-11-28 | Added | RELATION | is a GO:0044702 (single organism reproductive process) |
2013-05-09 | Deleted | RELATION | is a GO:0030154 (cell differentiation) |
2013-05-09 | Added | RELATION | is a GO:0030855 (epithelial cell differentiation) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2006-11-10 | Added | TERM | Sertoli cell differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-12-17 | Added | DEFINITION | The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. |
2010-12-17 | Deleted | DEFINITION | The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. |
2008-05-13 | Added | DEFINITION | The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. |
2008-05-12 | Deleted | DEFINITION | The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. |
2006-11-14 | Added | DEFINITION | The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-08-13 | Deleted | RELATION | is a GO:0044702 (single organism reproductive process) |
2016-08-06 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2016-06-22 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2014-07-30 | Deleted | RELATION | is a GO:0048610 (obsolete cellular process involved in reproduction) |
2013-11-28 | Added | RELATION | is a GO:0044702 (single organism reproductive process) |
2013-05-09 | Deleted | RELATION | is a GO:0030154 (cell differentiation) |
2013-05-09 | Added | RELATION | is a GO:0030855 (epithelial cell differentiation) |
2010-03-19 | Added | RELATION | is a GO:0003006 (developmental process involved in reproduction) |
2010-03-19 | Added | RELATION | is a GO:0048610 (obsolete cellular process involved in reproduction) |
2008-04-01 | Updated | RELATION | is a GO:0030154 (cell differentiation) |
2008-04-01 | Updated | RELATION | part of GO:0008584 (male gonad development) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-22 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
2024-03-22 | Deleted | CONSTRAINT | in_taxon NCBITaxon:33213 (Bilateria) |
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33213 (Bilateria) |
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