GO:0060698
JSON
endoribonuclease inhibitor activity
Molecular Function
Definition (GO:0060698 GONUTS page)
Binds to and stops, prevents or reduces the activity of endoribonuclease.
Ancestor Chart
Ancestor chart for GO:0060698
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Annotating to catalytic activities using the IPI evidence code | Link |
| Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | P84995 | 5315 | GANOD_GANLU | GO:0008428 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16039755 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0060698 based on ALL annotations
The top 100 of 121 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
endoribonuclease inhibitor activity
|
45,626.26 | 100.00 | 4,343 | 4,343 |
|
ribonuclease inhibitor activity
|
8,112.47 | 14.88 | 2,073 | 11,659 |
|
regulation of RNA metabolic process
|
7,563.52 | 14.02 | 2,067 | 12,469 |
|
negative regulation of RNA catabolic process
|
9,860.52 | 13.18 | 1,097 | 5,076 |
|
enzyme binding
|
4,329.50 | 9.46 | 4,212 | 44,388 |
|
CTPase activity
|
11,770.61 | 2.10 | 97 | 376 |
|
negative regulation of calcium ion transport into cytosol
|
14,178.68 | 1.73 | 78 | 251 |
|
response to L-glutamate
|
12,620.03 | 1.72 | 78 | 282 |
|
neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
45,626.26 | 1.63 | 71 | 71 |
|
negative regulation of immunoglobulin production
|
8,973.59 | 1.53 | 71 | 361 |
| Totals | 22433 | 167401263 | ||
No co-occurrence statistics for GO:0060698 based on MANUAL annotations
The top 78 of 78 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
endoribonuclease inhibitor activity
|
31,367.40 | 100.00 | 45 | 45 |
|
cellular response to unfolded protein
|
7,896.69 | 23.68 | 36 | 143 |
|
negative regulation of apoptotic signaling pathway
|
6,202.59 | 18.72 | 35 | 177 |
|
negative regulation of RNA splicing
|
5,455.20 | 6.25 | 4 | 23 |
|
CTPase activity
|
4,481.06 | 5.80 | 4 | 28 |
|
negative regulation of calcium ion transport into cytosol
|
7,841.85 | 5.56 | 3 | 12 |
|
neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
31,367.40 | 4.44 | 2 | 2 |
|
negative regulation of immunoglobulin production
|
2,412.88 | 2.90 | 2 | 26 |
|
ribonuclease inhibitor activity
|
2,163.27 | 2.78 | 2 | 29 |
|
response to L-glutamate
|
1,960.46 | 2.67 | 2 | 32 |
| Totals | 346 | 1136536 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2022-12-12 | Deleted | RELATION | part of GO:0060702 (negative regulation of endoribonuclease activity) |
| 2021-04-20 | Deleted | DEFINITION | Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. |
| 2021-04-20 | Added | DEFINITION | Binds to and stops, prevents or reduces the activity of endoribonuclease. |
| 2010-06-15 | Added | RELATION | negatively regulates GO:0004521 (RNA endonuclease activity) |
| 2010-06-15 | Added | RELATION | part of GO:0060702 (negative regulation of endoribonuclease activity) |
| 2010-06-14 | Deleted | RELATION | negatively regulates GO:0004521 (RNA endonuclease activity) |
| 2010-06-14 | Deleted | RELATION | part of GO:0060702 (negative regulation of endoribonuclease activity) |
| 2010-06-08 | Added | RELATION | negatively regulates GO:0004521 (RNA endonuclease activity) |
| 2010-06-08 | Added | RELATION | part of GO:0060702 (negative regulation of endoribonuclease activity) |
| 2009-06-11 | Added | TERM | endoribonuclease inhibitor activity |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-06-11 | Added | TERM | endoribonuclease inhibitor activity |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-04-20 | Deleted | DEFINITION | Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. |
| 2021-04-20 | Added | DEFINITION | Binds to and stops, prevents or reduces the activity of endoribonuclease. |
| 2009-06-11 | Added | DEFINITION | Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2022-12-12 | Deleted | RELATION | part of GO:0060702 (negative regulation of endoribonuclease activity) |
| 2010-06-15 | Added | RELATION | negatively regulates GO:0004521 (RNA endonuclease activity) |
| 2010-06-15 | Added | RELATION | part of GO:0060702 (negative regulation of endoribonuclease activity) |
| 2010-06-14 | Deleted | RELATION | negatively regulates GO:0004521 (RNA endonuclease activity) |
| 2010-06-14 | Deleted | RELATION | part of GO:0060702 (negative regulation of endoribonuclease activity) |
| 2010-06-08 | Added | RELATION | negatively regulates GO:0004521 (RNA endonuclease activity) |
| 2010-06-08 | Added | RELATION | part of GO:0060702 (negative regulation of endoribonuclease activity) |
| 2009-06-11 | Added | RELATION | is a GO:0008428 (ribonuclease inhibitor activity) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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