This term is obsolete.

GO:0060718 JSON

chorionic trophoblast cell differentiation

Biological Process

Definition (GO:0060718 GONUTS page)

The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. PMID:16983341

444 annotations

Ancestor Chart

Ancestor chart for GO:0060718
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0060718

Child Term Relationship to
GO:0060718
chorionic trophoblast cell development
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0060718 chorionic trophoblast cell differentiation Only in Taxon 32525 Theria

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0011101 chorionic trophoblast cell

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0060718 based on ALL annotations
The top 100 of 162 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chorionic trophoblast cell differentiation
516,028.28 100.00 384 384
cell cycle comprising mitosis without cytokinesis
403,848.25 17.82 72 92
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
459,477.22 16.58 65 73
negative regulation of cytokinesis
97,202.01 14.02 136 722
regulation of chorionic trophoblast cell proliferation
209,636.48 13.57 65 160
positive regulation of DNA endoreduplication
82,856.96 12.42 136 847
trophoblast giant cell differentiation
80,515.05 12.02 132 846
male germ-line sex determination
146,440.47 11.60 63 222
placenta development
61,246.77 11.57 315 2,654
post-embryonic camera-type eye development
111,434.68 10.48 65 301
Totals 7020 3323766
No co-occurrence statistics for GO:0060718 based on MANUAL annotations
The top 100 of 125 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chorionic trophoblast cell differentiation
56,461.32 100.00 25 25
cell cycle comprising mitosis without cytokinesis
56,461.32 24.00 6 6
negative regulation of cytokinesis
16,525.26 22.22 12 41
male germ-line sex determination
16,467.89 16.67 7 24
positive regulation of DNA endoreduplication
8,065.90 12.37 12 84
hepatocyte differentiation
6,708.28 10.53 12 101
trophoblast giant cell differentiation
7,404.76 10.26 8 61
placenta development
5,182.44 8.92 19 207
regulation of chorionic trophoblast cell proliferation
22,584.53 7.14 2 5
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
22,584.53 7.14 2 5
Totals 379 144123

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:32525 (Theria)
2010-12-17 Added DEFINITION The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.
2010-12-17 Deleted DEFINITION The process whereby relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.
2009-06-16 Added RELATION part of GO:0060717 (chorion development)
2009-06-16 Added DEFINITION The process whereby relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.
2009-06-16 Added RELATION is a GO:0030154 (cell differentiation)
2009-06-16 Added TERM chorionic trophoblast cell differentiation
Timestamp Action Category Detail
2009-06-16 Added TERM chorionic trophoblast cell differentiation
Timestamp Action Category Detail
2010-12-17 Added DEFINITION The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.
2010-12-17 Deleted DEFINITION The process whereby relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.
2009-06-16 Added DEFINITION The process whereby relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.
Timestamp Action Category Detail
2009-06-16 Added RELATION part of GO:0060717 (chorion development)
2009-06-16 Added RELATION is a GO:0030154 (cell differentiation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:32525 (Theria)
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