This term is obsolete.

GO:0060920 JSON

cardiac pacemaker cell differentiation

Biological Process

Definition (GO:0060920 GONUTS page)

The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.

Acknowledgement

This term was created by the GO Consortium with support from: BHF image

1,448 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
pacemaker cell differentiation broad

Ancestor Chart

Ancestor chart for GO:0060920
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0060920

Child Term Relationship to
GO:0060920
atrioventricular node cell differentiation
is_a
cardiac pacemaker cell development
part_of
cardiac pacemaker cell fate commitment
part_of
sinoatrial node cell differentiation
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0060920 cardiac pacemaker cell differentiation Only in Taxon 33213 Bilateria

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A1D5NZN4 9031 A0A1D5NZN4_CHICK GO:0007507 1 NOT-qualified manual annotation exists with evidence code ECO:0000303 from this reference: PMID:17549728
NOT-qualified manual protein A0A8I6AM39 10116 A0A8I6AM39_RAT GO:0048738 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6IPB4 10116 A6IPB4_RAT GO:0048738 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein F1LQC5 10116 F1LQC5_RAT GO:0048738 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein F1RET2 7955 SMYD5_DANRE GO:0048738 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27377701
NOT-qualified manual protein F7FNP9 10116 F7FNP9_RAT GO:0007507 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0002072 nodal myocyte

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0060920 based on ALL annotations
The top 100 of 116 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cardiac pacemaker cell differentiation
1,071,092.20 100.00 182 182
atrioventricular node cell differentiation
1,071,092.20 57.69 105 105
response to resveratrol
720,927.50 45.06 105 156
sinoatrial valve development
1,071,092.20 42.31 77 77
glutamate secretion, neurotransmission
513,537.38 35.47 105 219
cardiac right atrium morphogenesis
509,099.40 28.84 77 162
NLRP3 inflammasome complex assembly
303,958.60 23.49 105 370
voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
285,443.34 22.29 105 394
regulation of branching morphogenesis of a nerve
331,221.30 21.75 77 249
sinoatrial node development
317,208.10 21.10 77 260
Totals 8803 6522837
No co-occurrence statistics for GO:0060920 based on MANUAL annotations
The top 100 of 107 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cardiac pacemaker cell differentiation
258,359.80 100.00 5 5
sinoatrial valve development
258,359.81 60.00 3 3
atrioventricular node cell differentiation
258,359.80 40.00 2 2
cardiac right atrium morphogenesis
129,179.91 37.50 3 6
response to resveratrol
57,413.29 16.67 2 9
sinoatrial node development
48,442.47 16.67 3 16
sinoatrial node cell development
40,793.65 14.29 3 19
sulfonylurea receptor binding
86,119.94 14.29 1 3
regulation of branching morphogenesis of a nerve
43,059.97 13.33 2 12
glutamate secretion, neurotransmission
30,395.27 10.00 2 17
Totals 192 79407

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33213 (Bilateria)
2012-09-17 Added SYNONYM pacemaker cell differentiation
2012-09-17 Updated TERM cardiac pacemaker cell differentiation
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
2009-10-01 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
2009-10-01 Added TERM pacemaker cell differentiation
2009-10-01 Added RELATION is a GO:0055007 (cardiac muscle cell differentiation)
Timestamp Action Category Detail
2012-09-17 Updated TERM cardiac pacemaker cell differentiation
2009-10-01 Added TERM pacemaker cell differentiation
Timestamp Action Category Detail
2012-09-17 Added SYNONYM pacemaker cell differentiation
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
2009-10-01 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
Timestamp Action Category Detail
2009-10-01 Added RELATION is a GO:0055007 (cardiac muscle cell differentiation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33213 (Bilateria)
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