This term is obsolete.

GO:0061077 JSON

chaperone-mediated protein folding

Biological Process

Definition (GO:0061077 GONUTS page)

The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.

306,912 annotations

Ancestor Chart

Ancestor chart for GO:0061077
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0061077

Child Term Relationship to
GO:0061077
positive regulation of chaperone-mediated protein folding
positively_regulates
chaperone cofactor-dependent protein refolding
is_a
regulation of chaperone-mediated protein folding
regulates
chaperone mediated protein folding independent of cofactor
is_a
negative regulation of chaperone-mediated protein folding
negatively_regulates

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P23284 9606 PPIB_HUMAN GO:0061077 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:20089953
NOT-qualified manual protein P24368 10116 PPIB_RAT GO:0061077 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q42512 3702 CR15A_ARATH GO:0061077 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18540080
NOT-qualified manual protein Q54DU0 44689 Q54DU0_DICDI GO:0061077 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:24137657

Cross-references

Database ID Description
InterPro IPR001829 Pili assembly chaperone, bacterial
InterPro IPR030873 Beta-barrel assembly-enhancing protease
InterPro IPR043183 DnaJ homolog subfamily B member 2/6-like
InterPro IPR044609 Peptidyl-prolyl cis-trans isomerase FKBP2/11

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0061077 based on ALL annotations
The top 100 of 1,059 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chaperone-mediated protein folding
1,532.96 100.00 129,263 129,263
'de novo' cotranslational protein folding
1,225.91 28.15 39,143 48,947
protein unfolding
789.05 23.56 39,141 76,043
obsolete protein maturation by protein folding
1,358.06 23.08 30,749 34,709
protein folding chaperone
462.52 19.52 46,020 152,527
protein stabilization
513.32 16.54 31,829 95,053
RNA polymerase II CTD heptapeptide repeat P3 isomerase activity
224.09 10.23 32,831 224,589
RNA polymerase II CTD heptapeptide repeat P6 isomerase activity
224.09 10.23 32,831 224,589
peptidyl-prolyl cis-trans isomerase activity
161.68 9.01 49,381 468,194
ribosome binding
118.55 6.56 39,144 506,182
Totals 909924 74722648
No co-occurrence statistics for GO:0061077 based on MANUAL annotations
The top 100 of 773 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chaperone-mediated protein folding
1,085.79 100.00 1,300 1,300
protein folding chaperone
191.15 13.83 510 2,897
peptidyl-prolyl cis-trans isomerase activity
179.37 13.42 542 3,281
protein unfolding
422.40 10.48 163 419
'de novo' cotranslational protein folding
394.62 10.38 165 454
protein folding chaperone complex
445.45 5.65 80 195
ribosome binding
64.60 4.23 166 2,790
protein-folding chaperone binding
55.36 3.83 173 3,393
outer membrane-bounded periplasmic space
82.53 3.44 77 1,013
Hsp90 protein binding
75.43 3.28 76 1,094
Totals 5694 350894

Change Log

Timestamp Action Category Detail
2010-06-04 Deleted DEFINITION The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-06-04 Added DEFINITION The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-04-08 Added TERM chaperone-mediated protein folding
2010-04-08 Added DEFINITION The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-04-08 Added RELATION is a GO:0006457 (protein folding)
Timestamp Action Category Detail
2010-04-08 Added TERM chaperone-mediated protein folding
Timestamp Action Category Detail
2010-06-04 Deleted DEFINITION The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-06-04 Added DEFINITION The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-04-08 Added DEFINITION The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
Timestamp Action Category Detail
2010-04-08 Added RELATION is a GO:0006457 (protein folding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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