This term is obsolete.

GO:0061077 JSON

chaperone-mediated protein folding

Biological Process

Definition (GO:0061077 GONUTS page)

The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.

300,367 annotations

Ancestor Chart

Ancestor chart for GO:0061077
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0061077

Child Term Relationship to
GO:0061077
negative regulation of chaperone-mediated protein folding
negatively_regulates
regulation of chaperone-mediated protein folding
regulates
positive regulation of chaperone-mediated protein folding
positively_regulates
chaperone mediated protein folding independent of cofactor
is_a
chaperone cofactor-dependent protein refolding
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P23284 9606 PPIB_HUMAN GO:0061077 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:20089953
NOT-qualified manual protein P24368 10116 PPIB_RAT GO:0061077 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q42512 3702 CR15A_ARATH GO:0061077 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18540080
NOT-qualified manual protein Q54DU0 44689 Q54DU0_DICDI GO:0061077 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:24137657

Cross-references

Database ID Description
InterPro IPR001829 Pili assembly chaperone, bacterial
InterPro IPR030873 Beta-barrel assembly-enhancing protease
InterPro IPR043183 DnaJ homolog subfamily B member 2/6-like
InterPro IPR044609 Peptidyl-prolyl cis-trans isomerase FKBP2/11

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0061077 based on ALL annotations
The top 100 of 1,079 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chaperone-mediated protein folding
1,538.06 100.00 126,743 126,743
'de novo' cotranslational protein folding
1,235.77 28.33 38,574 48,010
protein unfolding
790.15 23.63 38,572 75,082
protein maturation by protein folding
1,361.79 23.33 30,492 34,439
protein folding chaperone
465.93 19.60 45,254 149,386
protein stabilization
519.93 16.73 31,545 93,316
RNA polymerase II CTD heptapeptide repeat P3 isomerase activity
225.45 10.38 33,259 226,896
RNA polymerase II CTD heptapeptide repeat P6 isomerase activity
225.45 10.38 33,259 226,896
peptidyl-prolyl cis-trans isomerase activity
163.02 9.05 48,422 456,863
ribosome binding
120.15 6.63 38,575 493,807
Totals 901380 76498639
No co-occurrence statistics for GO:0061077 based on MANUAL annotations
The top 100 of 781 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chaperone-mediated protein folding
1,089.21 100.00 1,186 1,186
peptidyl-prolyl cis-trans isomerase activity
187.48 14.01 510 2,963
protein folding chaperone
187.92 13.47 451 2,614
protein unfolding
419.77 10.70 153 397
'de novo' cotranslational protein folding
400.06 10.67 155 422
protein folding chaperone complex
436.85 5.78 75 187
ribosome binding
66.22 4.34 156 2,566
protein-folding chaperone binding
61.59 4.28 177 3,130
Hsp90 protein binding
93.64 3.56 68 791
unfolded protein binding
43.91 3.55 274 6,796
Totals 5427 328355

Change Log

Timestamp Action Category Detail
2010-06-04 Deleted DEFINITION The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-06-04 Added DEFINITION The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-04-08 Added RELATION is a GO:0006457 (protein folding)
2010-04-08 Added DEFINITION The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-04-08 Added TERM chaperone-mediated protein folding
Timestamp Action Category Detail
2010-04-08 Added TERM chaperone-mediated protein folding
Timestamp Action Category Detail
2010-06-04 Deleted DEFINITION The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-06-04 Added DEFINITION The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
2010-04-08 Added DEFINITION The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
Timestamp Action Category Detail
2010-04-08 Added RELATION is a GO:0006457 (protein folding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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