GO:0061179
JSON
negative regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process
Definition (GO:0061179 GONUTS page)
Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
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negative regulation of insulin secretion in response to glucose | related |
negative regulation of insulin secretion involved in cellular response to glucose | exact |
Ancestor Chart
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
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signalling | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | D3ZAS9 | 10116 | D3ZAS9_RAT | GO:0061178 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:21494687 | |
NOT-qualified manual | protein | Q5BJP3 | 10116 | UFM1_RAT | GO:0061178 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:21494687 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0061179 based on ALL annotations
The top 100 of 427 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
420,126.70 | 100.00 | 464 | 464 |
negative regulation of adipose tissue development
|
210,063.33 | 17.88 | 101 | 202 |
phospholipase C-activating adrenergic receptor signaling pathway
|
410,003.16 | 17.38 | 81 | 83 |
negative regulation of release of sequestered calcium ion into cytosol
|
321,040.22 | 16.56 | 81 | 106 |
FK506 binding
|
138,899.03 | 12.90 | 81 | 245 |
positive regulation of sequestering of calcium ion
|
77,166.13 | 9.83 | 81 | 441 |
heterotrimeric G-protein binding
|
76,817.75 | 9.81 | 81 | 443 |
negative regulation of calcium-mediated signaling
|
52,350.17 | 7.75 | 79 | 634 |
fear response
|
49,657.27 | 7.37 | 76 | 643 |
neuronal action potential propagation
|
38,583.06 | 6.40 | 81 | 882 |
Totals | 4723 | 336768 |
No co-occurrence statistics for GO:0061179 based on MANUAL annotations
The top 100 of 337 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
18,721.73 | 100.00 | 69 | 69 |
negative regulation of steroid hormone biosynthetic process
|
17,384.46 | 18.57 | 13 | 14 |
operant conditioning
|
9,014.16 | 15.66 | 13 | 27 |
negative regulation of neuron projection regeneration
|
8,915.11 | 12.50 | 10 | 21 |
positive regulation of ARF protein signal transduction
|
7,200.66 | 11.76 | 10 | 26 |
positive regulation of focal adhesion disassembly
|
6,240.57 | 11.24 | 10 | 30 |
heat generation
|
6,240.57 | 10.34 | 9 | 27 |
positive regulation of lipid metabolic process
|
5,616.52 | 10.00 | 9 | 30 |
cellular response to lipid
|
4,955.75 | 9.57 | 9 | 34 |
positive regulation of keratinocyte migration
|
3,900.36 | 9.35 | 10 | 48 |
Totals | 602 | 11834 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2018-03-05 | Deleted | RELATION | is a GO:0032845 (negative regulation of homeostatic process) |
2015-04-10 | Added | SYNONYM | negative regulation of insulin secretion in response to glucose |
2015-04-10 | Deleted | SYNONYM | negative regulation of insulin secretion in response to glucose |
2014-10-18 | Added | RELATION | is a GO:0048585 (negative regulation of response to stimulus) |
2014-10-18 | Added | RELATION | is a GO:0032845 (negative regulation of homeostatic process) |
2011-04-03 | Updated | TERM | negative regulation of insulin secretion involved in cellular response to glucose stimulus |
2011-04-03 | Added | RELATION | negatively regulates GO:0035773 (insulin secretion involved in cellular response to glucose stimulus) |
2011-04-03 | Added | SYNONYM | negative regulation of insulin secretion involved in cellular response to glucose |
2010-07-15 | Added | TERM | negative regulation of insulin secretion involved in cellular response to glucose |
2010-07-15 | Added | RELATION | is a GO:0061178 (regulation of insulin secretion involved in cellular response to glucose stimulus) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-04-03 | Updated | TERM | negative regulation of insulin secretion involved in cellular response to glucose stimulus |
2010-07-15 | Added | TERM | negative regulation of insulin secretion involved in cellular response to glucose |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-04-10 | Added | SYNONYM | negative regulation of insulin secretion in response to glucose |
2015-04-10 | Deleted | SYNONYM | negative regulation of insulin secretion in response to glucose |
2011-04-03 | Added | SYNONYM | negative regulation of insulin secretion involved in cellular response to glucose |
2010-07-15 | Added | DEFINITION | Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. |
2010-07-15 | Added | SYNONYM | negative regulation of insulin secretion in response to glucose |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-03-05 | Deleted | RELATION | is a GO:0032845 (negative regulation of homeostatic process) |
2014-10-18 | Added | RELATION | is a GO:0048585 (negative regulation of response to stimulus) |
2014-10-18 | Added | RELATION | is a GO:0032845 (negative regulation of homeostatic process) |
2011-04-03 | Added | RELATION | negatively regulates GO:0035773 (insulin secretion involved in cellular response to glucose stimulus) |
2010-07-15 | Added | RELATION | is a GO:0061178 (regulation of insulin secretion involved in cellular response to glucose stimulus) |
2010-07-15 | Added | RELATION | is a GO:0046676 (negative regulation of insulin secretion) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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