GO:0061656
JSON
SUMO conjugating enzyme activity
Molecular Function
Definition (GO:0061656 GONUTS page)
Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y = Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
E2 | broad |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | P53817 | 10116 | PLAT3_RAT | GO:0016746 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0061656 based on ALL annotations
The top 100 of 109 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
SUMO conjugating enzyme activity
|
497,292.78 | 100.00 | 392 | 392 |
SUMO ligase complex
|
128,577.62 | 11.58 | 68 | 263 |
RING-like zinc finger domain binding
|
122,946.92 | 11.24 | 67 | 271 |
small protein activating enzyme binding
|
91,034.48 | 9.70 | 67 | 366 |
spectrosome organization
|
155,404.00 | 2.42 | 10 | 32 |
negative regulation melanotic encapsulation of foreign target
|
150,694.80 | 2.41 | 10 | 33 |
ubiquitin activating enzyme binding
|
124,323.21 | 2.37 | 10 | 40 |
negative regulation of hemocyte proliferation
|
85,740.14 | 2.27 | 10 | 58 |
negative regulation of lamellocyte differentiation
|
78,935.38 | 2.25 | 10 | 63 |
positive regulation of somatic stem cell division
|
50,231.60 | 2.08 | 10 | 99 |
Totals | 3405 | 49778611 |
No co-occurrence statistics for GO:0061656 based on MANUAL annotations
The top 90 of 90 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
SUMO conjugating enzyme activity
|
7,137.01 | 100.00 | 181 | 181 |
protein sumoylation
|
836.12 | 11.72 | 181 | 1,545 |
SUMO transferase activity
|
239.23 | 1.69 | 6 | 179 |
SUMO ligase complex
|
973.23 | 1.50 | 3 | 22 |
embryonic heart tube elongation
|
1,784.25 | 1.07 | 2 | 8 |
HLH domain binding
|
1,586.00 | 1.06 | 2 | 9 |
RING-like zinc finger domain binding
|
1,427.40 | 1.06 | 2 | 10 |
small protein activating enzyme binding
|
1,098.00 | 1.04 | 2 | 13 |
transferase complex
|
432.55 | 0.94 | 2 | 33 |
nuclear export
|
115.11 | 0.82 | 3 | 186 |
Totals | 689 | 714346 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-06-13 | Added | DEFINITION | Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y = Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue. |
2023-06-13 | Added | SYNONYM | E2 |
2023-06-13 | Deleted | SYNONYM | E2 |
2023-06-13 | Deleted | DEFINITION | Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue. |
2014-11-08 | Added | TERM | SUMO conjugating enzyme activity |
2014-11-08 | Added | DEFINITION | Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue. |
2014-11-08 | Added | RELATION | is a GO:0019789 (SUMO transferase activity) |
2014-11-08 | Added | SYNONYM | E2 |
2014-11-08 | Added | RELATION | is a GO:0061650 (ubiquitin-like protein conjugating enzyme activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-11-08 | Added | TERM | SUMO conjugating enzyme activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-06-13 | Added | DEFINITION | Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y = Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue. |
2023-06-13 | Added | SYNONYM | E2 |
2023-06-13 | Deleted | SYNONYM | E2 |
2023-06-13 | Deleted | DEFINITION | Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue. |
2014-11-08 | Added | DEFINITION | Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue. |
2014-11-08 | Added | SYNONYM | E2 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-11-08 | Added | RELATION | is a GO:0019789 (SUMO transferase activity) |
2014-11-08 | Added | RELATION | is a GO:0061650 (ubiquitin-like protein conjugating enzyme activity) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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