This term is obsolete.

GO:0061710 JSON

L-threonylcarbamoyladenylate synthase

Molecular Function

Definition (GO:0061710 GONUTS page)

Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.

19,265 annotations

Ancestor Chart

Ancestor chart for GO:0061710
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q4H4F3 1397 BTRD_NIACI GO:0016779 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17226887
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.7.7.87
MetaCyc RXN-14569
RHEA 36407

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:73682 L-threonylcarbamoyladenylate(2-)
has_participant CHEBI CHEBI:17544 hydrogencarbonate
has_participant CHEBI CHEBI:57926 L-threonine zwitterion
has_participant CHEBI CHEBI:30616 ATP(4-)
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:33019 diphosphate(3-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0061710 based on ALL annotations
The top 100 of 101 co-occurring terms
Co-occurring Term PR S% #Together #Compared
L-threonylcarbamoyladenylate synthase
10,121.96 100.00 19,259 19,259
regulation of translational fidelity
1,900.03 18.71 18,917 100,776
double-stranded RNA binding
987.74 9.76 19,216 196,918
tRNA threonylcarbamoyladenosine modification
352.56 3.16 4,891 140,419
tRNA binding
148.17 1.46 18,912 1,291,960
tRNA processing
107.67 1.06 18,596 1,748,269
nucleotidyltransferase activity
100.27 0.99 19,227 1,940,928
single-stranded telomeric DNA binding
128.07 0.58 201 15,886
negative regulation of transport
749.13 0.42 86 1,162
tRNA threonylcarbamoyladenosine metabolic process
59.09 0.38 201 34,429
Totals 158135 294806114
No co-occurrence statistics for GO:0061710 based on MANUAL annotations
The top 16 of 16 co-occurring terms
Co-occurring Term PR S% #Together #Compared
L-threonylcarbamoyladenylate synthase
184,542.70 100.00 7 7
negative regulation of transport
21,293.39 10.00 3 26
tRNA threonylcarbamoyladenosine modification
7,097.80 3.85 7 182
regulation of translational fidelity
5,102.56 2.75 6 217
nucleotidyltransferase activity
2,283.00 1.23 6 485
tRNA threonylcarbamoyladenosine metabolic process
798.89 0.42 1 231
tRNA binding
460.02 0.25 6 2,407
single-stranded telomeric DNA binding
168.22 0.09 1 1,097
telomere maintenance
147.75 0.08 1 1,249
double-stranded RNA binding
117.54 0.06 1 1,570
Totals 59 426271

Change Log

Timestamp Action Category Detail
2022-11-22 Deleted DEFINITION Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.
2022-11-22 Added DEFINITION Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.
2022-09-01 Added DEFINITION Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O.
2018-07-13 Deleted XREF RHEA:36410
2018-07-13 Added XREF RHEA:36407
2015-06-25 Added XREF RHEA:36410
2015-06-25 Added XREF EC:2.7.7.87
2015-06-25 Added XREF MetaCyc:RXN-14569
2015-06-25 Added TERM L-threonylcarbamoyladenylate synthase
Timestamp Action Category Detail
2015-06-25 Added TERM L-threonylcarbamoyladenylate synthase
Timestamp Action Category Detail
2022-11-22 Deleted DEFINITION Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.
2022-11-22 Added DEFINITION Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.
2022-09-01 Added DEFINITION Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O.
2015-06-25 Added DEFINITION Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O.
Timestamp Action Category Detail
2015-06-25 Added RELATION is a GO:0016779 (nucleotidyltransferase activity)
Timestamp Action Category Detail
2018-07-13 Deleted XREF RHEA:36410
2018-07-13 Added XREF RHEA:36407
2015-06-25 Added XREF RHEA:36410
2015-06-25 Added XREF EC:2.7.7.87
2015-06-25 Added XREF MetaCyc:RXN-14569
Timestamp Action Category Detail
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.