GO:0061749
JSON
forked DNA-dependent helicase activity
Molecular Function
Definition (GO:0061749 GONUTS page)
Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis. PMID:26277776
Ancestor Chart
Ancestor chart for GO:0061749
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A0G2JTU1 | 10116 | A0A0G2JTU1_RAT | GO:0003678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6IBW5 | 10116 | A6IBW5_RAT | GO:0003678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6KC96 | 10116 | A6KC96_RAT | GO:0004386 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6KFV6 | 10116 | A6KFV6_RAT | GO:0003678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | B5DFJ3 | 10116 | B5DFJ3_RAT | GO:0004386 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZDS8 | 10116 | D3ZDS8_RAT | GO:0003678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZG52 | 10116 | DNA2_RAT | GO:0003678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | D3ZS47 | 10116 | D3ZS47_RAT | GO:0003678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | E1BB03 | 9913 | ZRAB3_BOVIN | GO:0003678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | E1BMP7 | 9913 | DNA2_BOVIN | GO:0003678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 3.6.4.12 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0061749 based on ALL annotations
The top 100 of 1,906 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
forked DNA-dependent helicase activity
|
481.16 | 100.00 | 405,142 | 405,142 |
double-stranded DNA helicase activity
|
480.87 | 99.92 | 405,066 | 405,312 |
single-stranded 3'-5' DNA helicase activity
|
478.62 | 98.83 | 402,520 | 404,658 |
four-way junction helicase activity
|
404.39 | 83.60 | 402,598 | 479,025 |
DNA duplex unwinding
|
202.10 | 39.09 | 344,195 | 819,479 |
DNA helicase activity
|
226.25 | 37.28 | 260,408 | 553,794 |
chromatin extrusion motor activity
|
328.41 | 34.99 | 169,338 | 248,104 |
ATP-dependent H3-H4 histone complex chaperone activity
|
328.40 | 34.99 | 169,338 | 248,109 |
cohesin loader activity
|
328.13 | 34.98 | 169,338 | 248,310 |
chromatin looping
|
327.79 | 34.96 | 169,338 | 248,570 |
Totals | 7249735 | 106222995 |
No co-occurrence statistics for GO:0061749 based on MANUAL annotations
The top 100 of 111 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
forked DNA-dependent helicase activity
|
71,766.61 | 100.00 | 18 | 18 |
8-hydroxy-2'-deoxyguanosine DNA binding
|
39,145.43 | 26.09 | 6 | 11 |
telomeric G-quadruplex DNA binding
|
33,123.05 | 24.00 | 6 | 13 |
telomeric D-loop binding
|
30,757.12 | 23.08 | 6 | 14 |
positive regulation of strand invasion
|
57,413.29 | 21.05 | 4 | 5 |
regulation of DNA-templated DNA replication
|
32,621.19 | 20.83 | 5 | 11 |
double-stranded DNA helicase activity
|
17,941.65 | 19.05 | 8 | 32 |
Y-form DNA binding
|
13,396.43 | 17.72 | 14 | 75 |
3'-flap-structured DNA binding
|
23,922.21 | 15.38 | 4 | 12 |
MutLalpha complex binding
|
12,481.15 | 10.81 | 4 | 23 |
Totals | 438 | 131493 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-08-16 | Added | XREF | EC:3.6.4.12 |
2021-07-04 | Deleted | DEFINITION | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA. |
2021-07-04 | Added | DEFINITION | Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis. |
2019-05-25 | Added | DEFINITION | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA. |
2019-05-25 | Deleted | DEFINITION | Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA. |
2015-11-13 | Added | DEFINITION | Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA. |
2015-11-13 | Added | TERM | forked DNA-dependent helicase activity |
2015-11-13 | Added | RELATION | is a GO:0003678 (DNA helicase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-11-13 | Added | TERM | forked DNA-dependent helicase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-07-04 | Deleted | DEFINITION | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA. |
2021-07-04 | Added | DEFINITION | Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis. |
2019-05-25 | Added | DEFINITION | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA. |
2019-05-25 | Deleted | DEFINITION | Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA. |
2015-11-13 | Added | DEFINITION | Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-11-13 | Added | RELATION | is a GO:0003678 (DNA helicase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-08-16 | Added | XREF | EC:3.6.4.12 |
Timestamp | Action | Category | Detail |
---|
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