This term is obsolete.

GO:0061749 JSON

forked DNA-dependent helicase activity

Molecular Function

Definition (GO:0061749 GONUTS page)

Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis. PMID:26277776

405,153 annotations

Ancestor Chart

Ancestor chart for GO:0061749
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0G2JTU1 10116 A0A0G2JTU1_RAT GO:0003678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6IBW5 10116 A6IBW5_RAT GO:0003678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6KC96 10116 A6KC96_RAT GO:0004386 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6KFV6 10116 A6KFV6_RAT GO:0003678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B5DFJ3 10116 B5DFJ3_RAT GO:0004386 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZDS8 10116 D3ZDS8_RAT GO:0003678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZG52 10116 DNA2_RAT GO:0003678 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein D3ZS47 10116 D3ZS47_RAT GO:0003678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein E1BB03 9913 ZRAB3_BOVIN GO:0003678 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein E1BMP7 9913 DNA2_BOVIN GO:0003678 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024

Cross-references

Database ID Description
EC 3.6.4.12

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0061749 based on ALL annotations
The top 100 of 1,906 co-occurring terms
Co-occurring Term PR S% #Together #Compared
forked DNA-dependent helicase activity
481.16 100.00 405,142 405,142
double-stranded DNA helicase activity
480.87 99.92 405,066 405,312
single-stranded 3'-5' DNA helicase activity
478.62 98.83 402,520 404,658
four-way junction helicase activity
404.39 83.60 402,598 479,025
DNA duplex unwinding
202.10 39.09 344,195 819,479
DNA helicase activity
226.25 37.28 260,408 553,794
chromatin extrusion motor activity
328.41 34.99 169,338 248,104
ATP-dependent H3-H4 histone complex chaperone activity
328.40 34.99 169,338 248,109
cohesin loader activity
328.13 34.98 169,338 248,310
chromatin looping
327.79 34.96 169,338 248,570
Totals 7249735 106222995
No co-occurrence statistics for GO:0061749 based on MANUAL annotations
The top 100 of 111 co-occurring terms
Co-occurring Term PR S% #Together #Compared
forked DNA-dependent helicase activity
71,766.61 100.00 18 18
8-hydroxy-2'-deoxyguanosine DNA binding
39,145.43 26.09 6 11
telomeric G-quadruplex DNA binding
33,123.05 24.00 6 13
telomeric D-loop binding
30,757.12 23.08 6 14
positive regulation of strand invasion
57,413.29 21.05 4 5
regulation of DNA-templated DNA replication
32,621.19 20.83 5 11
double-stranded DNA helicase activity
17,941.65 19.05 8 32
Y-form DNA binding
13,396.43 17.72 14 75
3'-flap-structured DNA binding
23,922.21 15.38 4 12
MutLalpha complex binding
12,481.15 10.81 4 23
Totals 438 131493

Change Log

Timestamp Action Category Detail
2024-08-16 Added XREF EC:3.6.4.12
2021-07-04 Deleted DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA.
2021-07-04 Added DEFINITION Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis.
2019-05-25 Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA.
2019-05-25 Deleted DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA.
2015-11-13 Added DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA.
2015-11-13 Added TERM forked DNA-dependent helicase activity
2015-11-13 Added RELATION is a GO:0003678 (DNA helicase activity)
Timestamp Action Category Detail
2015-11-13 Added TERM forked DNA-dependent helicase activity
Timestamp Action Category Detail
2021-07-04 Deleted DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA.
2021-07-04 Added DEFINITION Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis.
2019-05-25 Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA.
2019-05-25 Deleted DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA.
2015-11-13 Added DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA.
Timestamp Action Category Detail
2015-11-13 Added RELATION is a GO:0003678 (DNA helicase activity)
Timestamp Action Category Detail
2024-08-16 Added XREF EC:3.6.4.12
Timestamp Action Category Detail
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