GO:0061849
JSON
telomeric G-quadruplex DNA binding
Molecular Function
Definition (GO:0061849 GONUTS page)
Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. PMID:16142245 PMID:9512530
Acknowledgement
This term was created by the GO Consortium with support from:
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Considerations when annotating from ChiP assay results | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | P40999 | 284812 | PMT1M_SCHPO | GO:0003677 | To remove over-annotation from InterPro entries IPR001525 and IPR018117; for this particular C5-methyltransferase family member, there is a Ser residue in the active site that may be responsible. Reported by InterPro on 19-10-2012 | |
NOT-qualified manual | protein | A0A0G2JX31 | 10116 | A0A0G2JX31_RAT | GO:0061849 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JY35 | 10116 | A0A0G2JY35_RAT | GO:0061849 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K0G0 | 10116 | A0A0G2K0G0_RAT | GO:0003677 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K736 | 10116 | A0A0G2K736_RAT | GO:0042162 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GWQ8 | 10116 | A0A1B0GWQ8_RAT | GO:0003677 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y5Z6 | 10116 | A0A8I5Y5Z6_RAT | GO:0003677 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5ZKC5 | 10116 | A0A8I5ZKC5_RAT | GO:0003677 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A2T0 | 10116 | A0A8I6A2T0_RAT | GO:0003677 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A7B9 | 10116 | A0A8I6A7B9_RAT | GO:0003677 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0061849 based on ALL annotations
The top 100 of 173 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
telomeric G-quadruplex DNA binding
|
900,704.00 | 100.00 | 220 | 220 |
8-hydroxy-2'-deoxyguanosine DNA binding
|
613,666.44 | 60.59 | 186 | 273 |
telomeric D-loop binding
|
500,092.34 | 50.41 | 186 | 335 |
positive regulation of strand invasion
|
835,704.60 | 39.65 | 90 | 97 |
3'-flap-structured DNA binding
|
711,082.06 | 36.89 | 90 | 114 |
bubble DNA binding
|
294,805.44 | 30.57 | 181 | 553 |
cellular response to camptothecin
|
234,854.02 | 19.04 | 91 | 349 |
regulation of growth rate
|
254,546.75 | 18.66 | 78 | 276 |
DNA/DNA annealing activity
|
167,273.60 | 14.70 | 91 | 490 |
MutLalpha complex binding
|
156,795.66 | 13.91 | 90 | 517 |
Totals | 6263 | 2278743 |
No co-occurrence statistics for GO:0061849 based on MANUAL annotations
The top 100 of 146 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
telomeric G-quadruplex DNA binding
|
117,627.75 | 100.00 | 12 | 12 |
8-hydroxy-2'-deoxyguanosine DNA binding
|
117,627.76 | 91.67 | 11 | 11 |
telomeric D-loop binding
|
92,421.81 | 73.33 | 11 | 14 |
positive regulation of DNA strand elongation
|
117,627.74 | 41.67 | 5 | 5 |
G-rich single-stranded DNA binding
|
84,019.82 | 35.71 | 5 | 7 |
positive regulation of strand invasion
|
94,102.20 | 30.77 | 4 | 5 |
telomere assembly
|
49,011.56 | 26.32 | 5 | 12 |
forked DNA-dependent helicase activity
|
35,288.32 | 23.08 | 6 | 20 |
telomeric D-loop disassembly
|
27,529.90 | 22.92 | 11 | 47 |
establishment of protein localization to telomere
|
29,406.94 | 20.00 | 6 | 24 |
Totals | 363 | 33872 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. |
2017-02-12 | Added | RELATION | is a GO:0051880 (G-quadruplex DNA binding) |
2017-02-12 | Added | DEFINITION | Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. |
2017-02-12 | Added | TERM | telomeric G-quadruplex DNA binding |
2017-02-12 | Added | RELATION | is a GO:0042162 (telomeric DNA binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-02-12 | Added | TERM | telomeric G-quadruplex DNA binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. |
2017-02-12 | Added | DEFINITION | Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-02-12 | Added | RELATION | is a GO:0051880 (G-quadruplex DNA binding) |
2017-02-12 | Added | RELATION | is a GO:0042162 (telomeric DNA binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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