This term is obsolete.

GO:0061849 JSON

telomeric G-quadruplex DNA binding

Molecular Function

Definition (GO:0061849 GONUTS page)

Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. PMID:16142245 PMID:9512530

Acknowledgement

This term was created by the GO Consortium with support from: BHF image

222 annotations

Ancestor Chart

Ancestor chart for GO:0061849
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link
Considerations when annotating from ChiP assay results Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein P40999 284812 PMT1M_SCHPO GO:0003677 To remove over-annotation from InterPro entries IPR001525 and IPR018117; for this particular C5-methyltransferase family member, there is a Ser residue in the active site that may be responsible. Reported by InterPro on 19-10-2012
NOT-qualified manual protein A0A0G2JX31 10116 A0A0G2JX31_RAT GO:0061849 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2JY35 10116 A0A0G2JY35_RAT GO:0061849 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K0G0 10116 A0A0G2K0G0_RAT GO:0003677 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K736 10116 A0A0G2K736_RAT GO:0042162 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1B0GWQ8 10116 A0A1B0GWQ8_RAT GO:0003677 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5Y5Z6 10116 A0A8I5Y5Z6_RAT GO:0003677 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZKC5 10116 A0A8I5ZKC5_RAT GO:0003677 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A2T0 10116 A0A8I6A2T0_RAT GO:0003677 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A7B9 10116 A0A8I6A7B9_RAT GO:0003677 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0061849 based on ALL annotations
The top 100 of 173 co-occurring terms
Co-occurring Term PR S% #Together #Compared
telomeric G-quadruplex DNA binding
900,704.00 100.00 220 220
8-hydroxy-2'-deoxyguanosine DNA binding
613,666.44 60.59 186 273
telomeric D-loop binding
500,092.34 50.41 186 335
positive regulation of strand invasion
835,704.60 39.65 90 97
3'-flap-structured DNA binding
711,082.06 36.89 90 114
bubble DNA binding
294,805.44 30.57 181 553
cellular response to camptothecin
234,854.02 19.04 91 349
regulation of growth rate
254,546.75 18.66 78 276
DNA/DNA annealing activity
167,273.60 14.70 91 490
MutLalpha complex binding
156,795.66 13.91 90 517
Totals 6263 2278743
No co-occurrence statistics for GO:0061849 based on MANUAL annotations
The top 100 of 146 co-occurring terms
Co-occurring Term PR S% #Together #Compared
telomeric G-quadruplex DNA binding
117,627.75 100.00 12 12
8-hydroxy-2'-deoxyguanosine DNA binding
117,627.76 91.67 11 11
telomeric D-loop binding
92,421.81 73.33 11 14
positive regulation of DNA strand elongation
117,627.74 41.67 5 5
G-rich single-stranded DNA binding
84,019.82 35.71 5 7
positive regulation of strand invasion
94,102.20 30.77 4 5
telomere assembly
49,011.56 26.32 5 12
forked DNA-dependent helicase activity
35,288.32 23.08 6 20
telomeric D-loop disassembly
27,529.90 22.92 11 47
establishment of protein localization to telomere
29,406.94 20.00 6 24
Totals 363 33872

Change Log

Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.
2017-02-12 Added RELATION is a GO:0051880 (G-quadruplex DNA binding)
2017-02-12 Added DEFINITION Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.
2017-02-12 Added TERM telomeric G-quadruplex DNA binding
2017-02-12 Added RELATION is a GO:0042162 (telomeric DNA binding)
Timestamp Action Category Detail
2017-02-12 Added TERM telomeric G-quadruplex DNA binding
Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.
2017-02-12 Added DEFINITION Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.
Timestamp Action Category Detail
2017-02-12 Added RELATION is a GO:0051880 (G-quadruplex DNA binding)
2017-02-12 Added RELATION is a GO:0042162 (telomeric DNA binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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