GO:0061929
JSON
gamma-glutamylaminecyclotransferase activity
Molecular Function
Definition (GO:0061929 GONUTS page)
Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline. PMID:20110353 PMID:6107907
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 4.3.2.8 | |
InterPro | IPR039126 | Gamma-glutamylaminecyclotransferase |
RHEA | 16961 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:32551 | L-lysinium(1+) |
has_participant | CHEBI | CHEBI:58402 | 5-oxo-L-prolinate |
has_participant | CHEBI | CHEBI:133752 | epsilon-(gamma-glutamyl)lysine dizwitterion |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0061929 based on ALL annotations
The top 39 of 39 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
gamma-glutamylaminecyclotransferase activity
|
36,893.48 | 100.00 | 5,371 | 5,371 |
modified amino acid catabolic process
|
36,766.26 | 16.13 | 867 | 870 |
cytosol
|
13.74 | 0.04 | 5,210 | 13,989,509 |
transferase activity
|
8.99 | 0.02 | 1,734 | 7,114,403 |
acyltransferase activity
|
7.98 | 0.02 | 572 | 2,644,090 |
lyase activity
|
7.40 | 0.02 | 907 | 4,523,172 |
amidine-lyase activity
|
18,446.74 | 0.02 | 1 | 2 |
mitochondrial matrix
|
3.34 | 0.01 | 20 | 220,932 |
biological_process
|
2.21 | 0.01 | 4 | 66,641 |
gamma-glutamylcyclotransferase activity
|
2.43 | 0.00 | 1 | 15,191 |
Totals | 14786 | 164046727 |
No co-occurrence statistics for GO:0061929 based on MANUAL annotations
The top 12 of 12 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
gamma-glutamylaminecyclotransferase activity
|
128,321.19 | 100.00 | 11 | 11 |
modified amino acid catabolic process
|
93,324.50 | 57.14 | 8 | 11 |
lysozyme activity
|
394.83 | 0.30 | 1 | 325 |
chitinase activity
|
111.49 | 0.09 | 1 | 1,151 |
peptidase activity
|
75.35 | 0.06 | 1 | 1,703 |
extracellular exosome
|
47.56 | 0.04 | 1 | 2,698 |
mitochondrial matrix
|
30.37 | 0.02 | 1 | 4,225 |
protein homodimerization activity
|
24.42 | 0.02 | 1 | 5,255 |
cytosol
|
12.89 | 0.01 | 9 | 89,580 |
protein binding
|
3.07 | 0.00 | 1 | 41,833 |
Totals | 37 | 276023 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-06-22 | Added | XREF | RHEA:16961 |
2018-03-09 | Added | XREF | EC:4.3.2.8 |
2017-08-31 | Added | TERM | gamma-glutamylaminecyclotransferase activity |
2017-08-31 | Added | RELATION | is a GO:0016842 (amidine-lyase activity) |
2017-08-31 | Added | DEFINITION | Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-08-31 | Added | TERM | gamma-glutamylaminecyclotransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-08-31 | Added | DEFINITION | Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-08-31 | Added | RELATION | is a GO:0016842 (amidine-lyase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-06-22 | Added | XREF | RHEA:16961 |
2018-03-09 | Added | XREF | EC:4.3.2.8 |
Timestamp | Action | Category | Detail |
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