GO:0070038
JSON
rRNA (pseudouridine-N3-)-methyltransferase activity
Molecular Function
Definition (GO:0070038 GONUTS page)
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.
Ancestor Chart
Ancestor chart for GO:0070038
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Annotating to catalytic activities using the IPI evidence code | Link |
| Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
| NOT-qualified manual | protein | A0A8I5YBY9 | 10116 | A0A8I5YBY9_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | A0A8I6AGH5 | 10116 | A0A8I6AGH5_RAT | GO:0008168 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | A2VDP2 | 9913 | PCMD1_BOVIN | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
| NOT-qualified manual | protein | A6JFH4 | 10116 | A6JFH4_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | A6JFH5 | 10116 | A6JFH5_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | A7XRZ1 | 227321 | TDIE_EMENI | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17704773 | |
| NOT-qualified manual | protein | D3Z930 | 10116 | D3Z930_RAT | GO:0008168 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | D4A629 | 10116 | D4A629_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0070038 based on ALL annotations
The top 23 of 23 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
rRNA (pseudouridine-N3-)-methyltransferase activity
|
7,472.75 | 100.00 | 26,517 | 26,517 |
|
rRNA methylation
|
592.64 | 7.93 | 26,517 | 334,361 |
|
rRNA processing
|
176.31 | 2.36 | 26,517 | 1,123,906 |
|
methylation
|
54.40 | 0.73 | 26,517 | 3,642,626 |
|
methyltransferase activity
|
52.27 | 0.70 | 26,517 | 3,790,987 |
|
cytoplasm
|
7.77 | 0.10 | 26,517 | 25,503,657 |
|
cellular_component
|
0.96 | 0.01 | 8 | 62,590 |
|
biological_process
|
0.90 | 0.01 | 8 | 66,641 |
|
molecular_function
|
0.86 | 0.01 | 8 | 69,480 |
|
negative regulation of ribosome biogenesis
|
0.55 | 0.00 | 3 | 40,662 |
| Totals | 159184 | 128232163 | ||
No co-occurrence statistics for GO:0070038 based on MANUAL annotations
The top 7 of 7 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
rRNA (pseudouridine-N3-)-methyltransferase activity
|
1,411,533.00 | 100.00 | 1 | 1 |
|
rRNA methylation
|
1,607.67 | 0.11 | 1 | 878 |
|
rRNA base methylation
|
1,157.94 | 0.08 | 1 | 1,219 |
|
ribosome binding
|
505.93 | 0.04 | 1 | 2,790 |
|
protein homodimerization activity
|
268.61 | 0.02 | 1 | 5,255 |
|
protein binding
|
33.74 | 0.00 | 1 | 41,833 |
|
cytoplasm
|
7.15 | 0.00 | 1 | 197,513 |
| Totals | 7 | 249489 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-10-02 | Added | TERM | rRNA (pseudouridine-N3-)-methyltransferase activity |
| 2008-10-02 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine. |
| 2008-10-02 | Added | RELATION | is a GO:0070037 (rRNA (pseudouridine) methyltransferase activity) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-10-02 | Added | TERM | rRNA (pseudouridine-N3-)-methyltransferase activity |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-10-02 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-10-02 | Added | RELATION | is a GO:0070037 (rRNA (pseudouridine) methyltransferase activity) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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