GO:0070080
JSON
titin Z domain binding
Molecular Function
Definition (GO:0070080 GONUTS page)
Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Z repeat domain binding | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0070080 based on ALL annotations
The top 94 of 94 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
titin Z domain binding
|
241,859.55 | 100.00 | 806 | 806 |
skeletal muscle myosin thick filament assembly
|
204,096.00 | 75.56 | 708 | 839 |
sarcomerogenesis
|
195,698.90 | 72.76 | 708 | 875 |
detection of muscle stretch
|
184,721.19 | 69.07 | 708 | 927 |
titin binding
|
143,126.86 | 59.18 | 806 | 1,362 |
skeletal muscle thin filament assembly
|
137,539.39 | 52.72 | 708 | 1,245 |
cardiac muscle tissue morphogenesis
|
92,760.86 | 36.42 | 708 | 1,846 |
cardiac myofibril assembly
|
49,821.52 | 20.03 | 708 | 3,437 |
actin filament uncapping
|
241,859.52 | 12.16 | 98 | 98 |
negative regulation of potassium ion transport
|
84,650.84 | 9.92 | 98 | 280 |
Totals | 13716 | 158800255 |
No co-occurrence statistics for GO:0070080 based on MANUAL annotations
The top 74 of 74 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
titin Z domain binding
|
161,474.88 | 100.00 | 8 | 8 |
actin filament uncapping
|
161,474.88 | 62.50 | 5 | 5 |
phospholipase C-activating angiotensin-activated signaling pathway
|
73,397.66 | 35.71 | 5 | 11 |
microspike assembly
|
50,460.90 | 26.32 | 5 | 16 |
negative regulation of potassium ion transport
|
32,294.98 | 17.86 | 5 | 25 |
positive regulation of endocytic recycling
|
23,746.31 | 13.51 | 5 | 34 |
positive regulation of potassium ion transport
|
23,067.84 | 13.16 | 5 | 35 |
titin binding
|
18,721.73 | 11.59 | 8 | 69 |
FATZ binding
|
18,721.73 | 11.59 | 8 | 69 |
detection of muscle stretch
|
13,456.24 | 7.32 | 3 | 36 |
Totals | 281 | 333500 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2008-11-07 | Deleted | DEFINITION | Interacting selectively with the titin Z domain, which recognises and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2008-11-07 | Added | DEFINITION | Interacting selectively with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2008-10-21 | Added | TERM | titin Z domain binding |
2008-10-21 | Added | DEFINITION | Interacting selectively with the titin Z domain, which recognises and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2008-10-21 | Added | RELATION | is a GO:0019904 (protein domain specific binding) |
2008-10-21 | Added | SYNONYM | Z repeat domain binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-10-21 | Added | TERM | titin Z domain binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2008-11-07 | Deleted | DEFINITION | Interacting selectively with the titin Z domain, which recognises and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2008-11-07 | Added | DEFINITION | Interacting selectively with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2008-10-21 | Added | DEFINITION | Interacting selectively with the titin Z domain, which recognises and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. |
2008-10-21 | Added | SYNONYM | Z repeat domain binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-10-21 | Added | RELATION | is a GO:0019904 (protein domain specific binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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