GO:0070205
JSON
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
Molecular Function
Definition (GO:0070205 GONUTS page)
Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
YfbB | related |
MenH | related |
6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity | related |
SHCHC synthase activity | related |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 4.2.99.20 | |
InterPro | IPR022485 | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase |
KEGG_REACTION | R08166 | |
MetaCyc | RXN-9310 | |
RHEA | 25597 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15361 | pyruvate |
has_participant | CHEBI | CHEBI:58818 | (1R,2S,5S,6S)-2-(3-carboxylatopropanoyl)-5-[(1-carboxylatovinyl)oxy]-6-hydroxycyclohex-3-ene-1-carboxylate |
has_participant | CHEBI | CHEBI:58689 | (1R,6R)-2-(3-carboxylatopropanoyl)-6-hydroxycyclohexa-2,4-diene-1-carboxylate |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0046410 | obsolete 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity | consider GO:0070205 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0070205 based on ALL annotations
The top 68 of 68 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
|
31,513.18 | 100.00 | 6,288 | 6,288 |
menaquinone biosynthetic process
|
1,118.79 | 3.53 | 5,373 | 151,342 |
phylloquinone biosynthetic process
|
1,318.48 | 2.36 | 324 | 7,744 |
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity
|
510.79 | 1.14 | 236 | 14,560 |
amino acid catabolic process
|
102.56 | 0.30 | 245 | 75,279 |
photosystem I stabilization
|
12,891.76 | 0.29 | 18 | 44 |
mycophenolic acid acyl-glucuronide esterase activity
|
5,682.70 | 0.17 | 11 | 61 |
lyase activity
|
43.64 | 0.14 | 6,264 | 4,523,172 |
acylglycerol catabolic process
|
27.67 | 0.08 | 37 | 42,132 |
thiamine pyrophosphate binding
|
20.19 | 0.06 | 256 | 399,572 |
Totals | 21444 | 175187659 |
No co-occurrence statistics for GO:0070205 based on MANUAL annotations
The top 3 of 3 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
|
1,411,533.00 | 100.00 | 1 | 1 |
menaquinone biosynthetic process
|
8,254.58 | 0.58 | 1 | 171 |
cytosol
|
15.76 | 0.00 | 1 | 89,580 |
Totals | 3 | 89752 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity |
2020-10-08 | Deleted | SYNONYM | SHCHC synthase activity |
2020-10-08 | Deleted | SYNONYM | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity |
2020-10-08 | Added | SYNONYM | SHCHC synthase activity |
2020-10-08 | Deleted | SYNONYM | 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity |
2020-10-08 | Added | SYNONYM | 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity |
2019-06-20 | Deleted | XREF | KEGG:R08166 |
2019-06-20 | Added | XREF | KEGG_REACTION:R08166 |
2018-07-13 | Added | XREF | RHEA:25597 |
2018-07-13 | Deleted | XREF | RHEA:25600 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-01-12 | Added | TERM | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity |
2020-10-08 | Deleted | SYNONYM | SHCHC synthase activity |
2020-10-08 | Deleted | SYNONYM | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity |
2020-10-08 | Added | SYNONYM | SHCHC synthase activity |
2020-10-08 | Deleted | SYNONYM | 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity |
2020-10-08 | Added | SYNONYM | 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity |
2011-01-13 | Added | SYNONYM | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity |
2011-01-13 | Deleted | SYNONYM | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate. |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate. |
2009-01-12 | Added | SYNONYM | 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity |
2009-01-12 | Added | SYNONYM | MenH |
2009-01-12 | Added | SYNONYM | SHCHC synthase activity |
2009-01-12 | Added | SYNONYM | YfbB |
2009-01-12 | Added | SYNONYM | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity |
2009-01-12 | Added | DEFINITION | Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-01-12 | Added | RELATION | is a GO:0016835 (carbon-oxygen lyase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Deleted | XREF | KEGG:R08166 |
2019-06-20 | Added | XREF | KEGG_REACTION:R08166 |
2018-07-13 | Added | XREF | RHEA:25597 |
2018-07-13 | Deleted | XREF | RHEA:25600 |
2010-10-11 | Added | XREF | RHEA:25600 |
2010-10-11 | Added | XREF | KEGG:R08166 |
2009-01-12 | Added | XREF | MetaCyc:RXN-9310 |
2009-01-12 | Added | XREF | EC:4.2.99.20 |
Timestamp | Action | Category | Detail |
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