This term is obsolete.

GO:0070205 JSON

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity

Molecular Function

Definition (GO:0070205 GONUTS page)

Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.

6,289 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
YfbB related
MenH related
6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity related
SHCHC synthase activity related
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity related

Ancestor Chart

Ancestor chart for GO:0070205
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 4.2.99.20
InterPro IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
KEGG_REACTION R08166
MetaCyc RXN-9310
RHEA 25597

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15361 pyruvate
has_participant CHEBI CHEBI:58818 (1R,2S,5S,6S)-2-(3-carboxylatopropanoyl)-5-[(1-carboxylatovinyl)oxy]-6-hydroxycyclohex-3-ene-1-carboxylate
has_participant CHEBI CHEBI:58689 (1R,6R)-2-(3-carboxylatopropanoyl)-6-hydroxycyclohexa-2,4-diene-1-carboxylate

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0046410 obsolete 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity consider GO:0070205

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0070205 based on ALL annotations
The top 68 of 68 co-occurring terms
Co-occurring Term PR S% #Together #Compared
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
31,513.18 100.00 6,288 6,288
menaquinone biosynthetic process
1,118.79 3.53 5,373 151,342
phylloquinone biosynthetic process
1,318.48 2.36 324 7,744
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity
510.79 1.14 236 14,560
amino acid catabolic process
102.56 0.30 245 75,279
photosystem I stabilization
12,891.76 0.29 18 44
mycophenolic acid acyl-glucuronide esterase activity
5,682.70 0.17 11 61
lyase activity
43.64 0.14 6,264 4,523,172
acylglycerol catabolic process
27.67 0.08 37 42,132
thiamine pyrophosphate binding
20.19 0.06 256 399,572
Totals 21444 175187659
No co-occurrence statistics for GO:0070205 based on MANUAL annotations
The top 3 of 3 co-occurring terms
Co-occurring Term PR S% #Together #Compared
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
1,411,533.00 100.00 1 1
menaquinone biosynthetic process
8,254.58 0.58 1 171
cytosol
15.76 0.00 1 89,580
Totals 3 89752

Change Log

Timestamp Action Category Detail
2020-10-08 Added SYNONYM 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity
2020-10-08 Deleted SYNONYM SHCHC synthase activity
2020-10-08 Deleted SYNONYM 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity
2020-10-08 Added SYNONYM SHCHC synthase activity
2020-10-08 Deleted SYNONYM 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity
2020-10-08 Added SYNONYM 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity
2019-06-20 Deleted XREF KEGG:R08166
2019-06-20 Added XREF KEGG_REACTION:R08166
2018-07-13 Added XREF RHEA:25597
2018-07-13 Deleted XREF RHEA:25600
Timestamp Action Category Detail
2009-01-12 Added TERM 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
Timestamp Action Category Detail
2020-10-08 Added SYNONYM 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity
2020-10-08 Deleted SYNONYM SHCHC synthase activity
2020-10-08 Deleted SYNONYM 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity
2020-10-08 Added SYNONYM SHCHC synthase activity
2020-10-08 Deleted SYNONYM 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity
2020-10-08 Added SYNONYM 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity
2011-01-13 Added SYNONYM 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity
2011-01-13 Deleted SYNONYM 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate.
2010-10-11 Added DEFINITION Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.
2009-01-12 Added SYNONYM 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity
2009-01-12 Added SYNONYM MenH
2009-01-12 Added SYNONYM SHCHC synthase activity
2009-01-12 Added SYNONYM YfbB
2009-01-12 Added SYNONYM 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity
2009-01-12 Added DEFINITION Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate.
Timestamp Action Category Detail
2009-01-12 Added RELATION is a GO:0016835 (carbon-oxygen lyase activity)
Timestamp Action Category Detail
2019-06-20 Deleted XREF KEGG:R08166
2019-06-20 Added XREF KEGG_REACTION:R08166
2018-07-13 Added XREF RHEA:25597
2018-07-13 Deleted XREF RHEA:25600
2010-10-11 Added XREF RHEA:25600
2010-10-11 Added XREF KEGG:R08166
2009-01-12 Added XREF MetaCyc:RXN-9310
2009-01-12 Added XREF EC:4.2.99.20
Timestamp Action Category Detail
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