This term is obsolete.

GO:0070419 JSON

nonhomologous end joining complex

Cellular Component

Definition (GO:0070419 GONUTS page)

A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends. PMID:17072889 PMID:17938628

16,392 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
non-homologous end joining complex exact
NHEJ complex exact

Ancestor Chart

Ancestor chart for GO:0070419
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0070419

Child Term Relationship to
GO:0070419
DNA-dependent protein kinase-DNA ligase 4 complex
is_a
DNA ligase IV complex
is_a
Ku-DNA ligase complex
is_a

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0070419 based on ALL annotations
The top 100 of 218 co-occurring terms
Co-occurring Term PR S% #Together #Compared
nonhomologous end joining complex
148,242.42 100.00 1,315 1,315
DNA-dependent protein kinase complex
90,666.13 18.40 274 448
regulation of smooth muscle cell proliferation
59,950.98 15.99 275 680
pro-B cell differentiation
104,272.21 11.99 166 236
5'-deoxyribose-5-phosphate lyase activity
40,582.68 10.56 193 705
DNA-dependent protein kinase-DNA ligase 4 complex
18,034.67 10.47 564 4,636
T cell receptor V(D)J recombination
60,730.36 10.41 161 393
double-strand break repair via classical nonhomologous end joining
32,500.57 9.74 196 894
FHA domain binding
148,242.44 7.53 99 99
positive regulation of chromosome organization
78,435.14 7.12 100 189
Totals 15828 1325324
No co-occurrence statistics for GO:0070419 based on MANUAL annotations
The top 100 of 177 co-occurring terms
Co-occurring Term PR S% #Together #Compared
nonhomologous end joining complex
19,572.71 100.00 66 66
DNA-dependent protein kinase complex
14,303.14 26.03 19 26
DNA-dependent protein kinase-DNA ligase 4 complex
4,822.26 20.00 34 138
regulation of smooth muscle cell proliferation
6,634.82 19.05 20 59
immunoglobulin V(D)J recombination
5,382.50 17.74 22 80
positive regulation of lymphocyte differentiation
10,148.81 17.72 14 27
pro-B cell differentiation
11,565.69 17.33 13 22
V(D)J recombination
4,630.10 16.06 22 93
DNA end binding
5,494.10 14.95 16 57
5'-deoxyribose-5-phosphate lyase activity
5,436.86 14.29 15 54
Totals 1008 24981

Change Log

Timestamp Action Category Detail
2020-11-03 Deleted RELATION part of GO:0005622 (intracellular anatomical structure)
2020-11-03 Added RELATION is a GO:0140535 (intracellular protein-containing complex)
2019-09-12 Deleted RELATION is a GO:0044424 (obsolete intracellular part)
2019-09-12 Added RELATION part of GO:0005622 (intracellular anatomical structure)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2016-10-05 Added RELATION is a GO:0043234 (protein complex)
2015-06-25 Deleted RELATION is a GO:0043234 (protein complex)
2015-06-18 Added RELATION capable of part of GO:0006303 (double-strand break repair via nonhomologous end joining)
2014-06-12 Added RELATION is a GO:1990391 (DNA repair complex)
2009-02-25 Added SYNONYM NHEJ complex
Timestamp Action Category Detail
2009-02-25 Added TERM nonhomologous end joining complex
Timestamp Action Category Detail
2009-02-25 Added SYNONYM NHEJ complex
2009-02-25 Added SYNONYM non-homologous end joining complex
2009-02-25 Added DEFINITION A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.
Timestamp Action Category Detail
2020-11-03 Deleted RELATION part of GO:0005622 (intracellular anatomical structure)
2020-11-03 Added RELATION is a GO:0140535 (intracellular protein-containing complex)
2019-09-12 Deleted RELATION is a GO:0044424 (obsolete intracellular part)
2019-09-12 Added RELATION part of GO:0005622 (intracellular anatomical structure)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2016-10-05 Added RELATION is a GO:0043234 (protein complex)
2015-06-25 Deleted RELATION is a GO:0043234 (protein complex)
2015-06-18 Added RELATION capable of part of GO:0006303 (double-strand break repair via nonhomologous end joining)
2014-06-12 Added RELATION is a GO:1990391 (DNA repair complex)
2009-02-25 Added RELATION is a GO:0044424 (obsolete intracellular part)
2009-02-25 Added RELATION is a GO:0043234 (protein complex)
Timestamp Action Category Detail
Timestamp Action Category Detail
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