GO:0070419
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nonhomologous end joining complex
Cellular Component
Definition (GO:0070419 GONUTS page)
A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends. PMID:17072889 PMID:17938628
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
non-homologous end joining complex | exact |
NHEJ complex | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0070419
Child Term | Relationship to GO:0070419 |
---|---|
DNA-dependent protein kinase-DNA ligase 4 complex
|
is_a |
DNA ligase IV complex
|
is_a |
Ku-DNA ligase complex
|
is_a |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0070419 based on ALL annotations
The top 100 of 218 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
nonhomologous end joining complex
|
148,242.42 | 100.00 | 1,315 | 1,315 |
DNA-dependent protein kinase complex
|
90,666.13 | 18.40 | 274 | 448 |
regulation of smooth muscle cell proliferation
|
59,950.98 | 15.99 | 275 | 680 |
pro-B cell differentiation
|
104,272.21 | 11.99 | 166 | 236 |
5'-deoxyribose-5-phosphate lyase activity
|
40,582.68 | 10.56 | 193 | 705 |
DNA-dependent protein kinase-DNA ligase 4 complex
|
18,034.67 | 10.47 | 564 | 4,636 |
T cell receptor V(D)J recombination
|
60,730.36 | 10.41 | 161 | 393 |
double-strand break repair via classical nonhomologous end joining
|
32,500.57 | 9.74 | 196 | 894 |
FHA domain binding
|
148,242.44 | 7.53 | 99 | 99 |
positive regulation of chromosome organization
|
78,435.14 | 7.12 | 100 | 189 |
Totals | 15828 | 1325324 |
No co-occurrence statistics for GO:0070419 based on MANUAL annotations
The top 100 of 177 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
nonhomologous end joining complex
|
19,572.71 | 100.00 | 66 | 66 |
DNA-dependent protein kinase complex
|
14,303.14 | 26.03 | 19 | 26 |
DNA-dependent protein kinase-DNA ligase 4 complex
|
4,822.26 | 20.00 | 34 | 138 |
regulation of smooth muscle cell proliferation
|
6,634.82 | 19.05 | 20 | 59 |
immunoglobulin V(D)J recombination
|
5,382.50 | 17.74 | 22 | 80 |
positive regulation of lymphocyte differentiation
|
10,148.81 | 17.72 | 14 | 27 |
pro-B cell differentiation
|
11,565.69 | 17.33 | 13 | 22 |
V(D)J recombination
|
4,630.10 | 16.06 | 22 | 93 |
DNA end binding
|
5,494.10 | 14.95 | 16 | 57 |
5'-deoxyribose-5-phosphate lyase activity
|
5,436.86 | 14.29 | 15 | 54 |
Totals | 1008 | 24981 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-03 | Deleted | RELATION | part of GO:0005622 (intracellular anatomical structure) |
2020-11-03 | Added | RELATION | is a GO:0140535 (intracellular protein-containing complex) |
2019-09-12 | Deleted | RELATION | is a GO:0044424 (obsolete intracellular part) |
2019-09-12 | Added | RELATION | part of GO:0005622 (intracellular anatomical structure) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2016-10-05 | Added | RELATION | is a GO:0043234 (protein complex) |
2015-06-25 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2015-06-18 | Added | RELATION | capable of part of GO:0006303 (double-strand break repair via nonhomologous end joining) |
2014-06-12 | Added | RELATION | is a GO:1990391 (DNA repair complex) |
2009-02-25 | Added | SYNONYM | NHEJ complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-02-25 | Added | TERM | nonhomologous end joining complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-02-25 | Added | SYNONYM | NHEJ complex |
2009-02-25 | Added | SYNONYM | non-homologous end joining complex |
2009-02-25 | Added | DEFINITION | A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-03 | Deleted | RELATION | part of GO:0005622 (intracellular anatomical structure) |
2020-11-03 | Added | RELATION | is a GO:0140535 (intracellular protein-containing complex) |
2019-09-12 | Deleted | RELATION | is a GO:0044424 (obsolete intracellular part) |
2019-09-12 | Added | RELATION | part of GO:0005622 (intracellular anatomical structure) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2016-10-05 | Added | RELATION | is a GO:0043234 (protein complex) |
2015-06-25 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2015-06-18 | Added | RELATION | capable of part of GO:0006303 (double-strand break repair via nonhomologous end joining) |
2014-06-12 | Added | RELATION | is a GO:1990391 (DNA repair complex) |
2009-02-25 | Added | RELATION | is a GO:0044424 (obsolete intracellular part) |
2009-02-25 | Added | RELATION | is a GO:0043234 (protein complex) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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