GO:0070675
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hypoxanthine oxidase activity
Molecular Function
Definition (GO:0070675 GONUTS page)
Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
schardinger enzyme | related |
hypoxanthine-xanthine oxidase activity | broad |
Schardinger enzyme activity | related |
xanthine oxidoreductase activity | broad |
hypoxanthine:oxygen oxidoreductase activity | related |
hypoxanthine:O2 oxidoreductase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
Reactome | R-HSA-74247 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0070675 based on ALL annotations
The top 57 of 57 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
hypoxanthine oxidase activity
|
2,436,734.80 | 100.00 | 80 | 80 |
hypoxanthine dehydrogenase activity
|
2,051,987.10 | 84.21 | 80 | 95 |
negative regulation of vasculogenesis
|
2,030,612.40 | 83.33 | 80 | 96 |
hypoxanthine catabolic process
|
843,890.90 | 34.63 | 80 | 231 |
xanthine catabolic process
|
776,648.56 | 31.87 | 80 | 251 |
deoxyinosine catabolic process
|
665,320.06 | 27.30 | 80 | 293 |
deoxyguanosine catabolic process
|
658,577.00 | 27.03 | 80 | 296 |
deoxyadenosine catabolic process
|
541,496.60 | 22.22 | 80 | 360 |
GMP catabolic process
|
503,717.78 | 20.67 | 80 | 387 |
inosine catabolic process
|
435,131.22 | 17.86 | 80 | 448 |
Totals | 3367 | 85599472 |
No co-occurrence statistics for GO:0070675 based on MANUAL annotations
The top 49 of 49 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
hypoxanthine oxidase activity
|
645,899.50 | 100.00 | 2 | 2 |
response to azide
|
645,899.50 | 50.00 | 1 | 1 |
hypoxanthine dehydrogenase activity
|
322,949.75 | 50.00 | 2 | 4 |
xanthine oxidase activity
|
215,299.84 | 33.33 | 2 | 6 |
negative regulation of vasculogenesis
|
161,474.88 | 20.00 | 1 | 4 |
guanine catabolic process
|
117,436.27 | 18.18 | 2 | 11 |
deoxyguanosine catabolic process
|
107,649.92 | 16.67 | 2 | 12 |
deoxyinosine catabolic process
|
107,649.92 | 16.67 | 2 | 12 |
deoxyadenosine catabolic process
|
107,649.92 | 16.67 | 2 | 12 |
hypoxanthine catabolic process
|
99,369.16 | 15.38 | 2 | 13 |
Totals | 78 | 198573 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-02 | Added | XREF | Reactome:R-HSA-74247 |
2022-09-01 | Deleted | SYNONYM | hypoxanthine:O(2) oxidoreductase activity |
2020-10-08 | Added | SYNONYM | hypoxanthine:oxygen oxidoreductase activity |
2020-10-08 | Added | SYNONYM | hypoxanthine:O(2) oxidoreductase activity |
2020-10-08 | Added | SYNONYM | hypoxanthine:O2 oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | hypoxanthine:O2 oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | hypoxanthine:O(2) oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | hypoxanthine:oxygen oxidoreductase activity |
2009-06-11 | Added | SYNONYM | hypoxanthine:O2 oxidoreductase activity |
2009-06-11 | Added | SYNONYM | hypoxanthine:O(2) oxidoreductase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-06-11 | Added | TERM | hypoxanthine oxidase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Deleted | SYNONYM | hypoxanthine:O(2) oxidoreductase activity |
2020-10-08 | Added | SYNONYM | hypoxanthine:oxygen oxidoreductase activity |
2020-10-08 | Added | SYNONYM | hypoxanthine:O(2) oxidoreductase activity |
2020-10-08 | Added | SYNONYM | hypoxanthine:O2 oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | hypoxanthine:O2 oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | hypoxanthine:O(2) oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | hypoxanthine:oxygen oxidoreductase activity |
2009-06-11 | Added | SYNONYM | hypoxanthine:O2 oxidoreductase activity |
2009-06-11 | Added | SYNONYM | hypoxanthine:O(2) oxidoreductase activity |
2009-06-11 | Added | DEFINITION | Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2. |
2009-06-11 | Added | SYNONYM | hypoxanthine:oxygen oxidoreductase activity |
2009-06-11 | Added | SYNONYM | xanthine oxidoreductase activity |
2009-06-11 | Added | SYNONYM | schardinger enzyme |
2009-06-11 | Added | SYNONYM | hypoxanthine-xanthine oxidase activity |
2009-06-11 | Added | SYNONYM | Schardinger enzyme activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-06-11 | Added | RELATION | is a GO:0016727 (oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-02 | Added | XREF | Reactome:R-HSA-74247 |
Timestamp | Action | Category | Detail |
---|
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