Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.
GO:0070695
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FHF complex
Cellular Component
Definition (GO:0070695 GONUTS page)
A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex). PMID:18799622
Comments
Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0070695 | FHF complex | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0D1E8X3 | 237631 | A0A0D1E8X3_USTMA | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A0G2JZ79 | 10116 | SIR1_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1L8G9S0 | 8355 | A0A1L8G9S0_XENLA | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4L3K3 | 6945 | A0A1S4L3K3_IXOSC | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A2K5ATM2 | 6239 | A0A2K5ATM2_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5ATM9 | 6239 | A0A2K5ATM9_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5ATP6 | 6239 | A0A2K5ATP6_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0070695 based on ALL annotations
The top 60 of 60 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
FHF complex
|
148,129.78 | 100.00 | 1,316 | 1,316 |
protein localization to perinuclear region of cytoplasm
|
85,874.98 | 28.32 | 469 | 809 |
early endosome to late endosome transport
|
12,841.82 | 8.67 | 1,316 | 15,180 |
lysosome organization
|
11,116.49 | 7.50 | 1,316 | 17,536 |
manchette assembly
|
17,313.87 | 4.51 | 90 | 770 |
endosome to lysosome transport
|
6,569.57 | 4.44 | 1,316 | 29,673 |
interkinetic nuclear migration
|
10,171.50 | 3.49 | 87 | 1,267 |
endosome organization
|
4,838.15 | 3.27 | 1,316 | 40,292 |
negative regulation of neurogenesis
|
6,545.09 | 2.72 | 87 | 1,969 |
neuronal stem cell population maintenance
|
6,339.05 | 2.67 | 87 | 2,033 |
Totals | 12647 | 139804376 |
No co-occurrence statistics for GO:0070695 based on MANUAL annotations
The top 45 of 45 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
FHF complex
|
26,912.48 | 100.00 | 48 | 48 |
protein localization to perinuclear region of cytoplasm
|
17,178.18 | 46.15 | 30 | 47 |
early endosome to late endosome transport
|
4,714.59 | 17.52 | 48 | 274 |
lysosome organization
|
2,410.07 | 8.96 | 48 | 536 |
endosome to lysosome transport
|
2,037.54 | 7.57 | 48 | 634 |
interkinetic nuclear migration
|
2,725.31 | 6.72 | 8 | 79 |
dynactin binding
|
1,755.16 | 5.08 | 9 | 138 |
endosome organization
|
1,302.22 | 4.84 | 48 | 992 |
manchette assembly
|
2,503.49 | 4.60 | 4 | 43 |
negative regulation of neurogenesis
|
1,571.53 | 4.52 | 8 | 137 |
Totals | 557 | 768563 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2019-09-12 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2019-09-12 | Added | RELATION | part of GO:0005737 (cytoplasm) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2009-06-11 | Added | RELATION | is a GO:0043234 (protein complex) |
2009-06-11 | Added | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2009-06-11 | Added | DEFINITION | A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex). |
2009-06-11 | Added | TERM | FHF complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-06-11 | Added | TERM | FHF complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-06-11 | Added | DEFINITION | A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex). |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-09-12 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2019-09-12 | Added | RELATION | part of GO:0005737 (cytoplasm) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2009-06-11 | Added | RELATION | is a GO:0043234 (protein complex) |
2009-06-11 | Added | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
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