This term is obsolete.
Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.

GO:0070695 JSON

FHF complex

Cellular Component

Definition (GO:0070695 GONUTS page)

A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex). PMID:18799622

Comments

Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.

1,343 annotations

Ancestor Chart

Ancestor chart for GO:0070695
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0070695 FHF complex Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 237631 A0A0D1E8X3_USTMA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATM9 6239 A0A2K5ATM9_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATP6 6239 A0A2K5ATP6_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0070695 based on ALL annotations
The top 60 of 60 co-occurring terms
Co-occurring Term PR S% #Together #Compared
FHF complex
148,129.78 100.00 1,316 1,316
protein localization to perinuclear region of cytoplasm
85,874.98 28.32 469 809
early endosome to late endosome transport
12,841.82 8.67 1,316 15,180
lysosome organization
11,116.49 7.50 1,316 17,536
manchette assembly
17,313.87 4.51 90 770
endosome to lysosome transport
6,569.57 4.44 1,316 29,673
interkinetic nuclear migration
10,171.50 3.49 87 1,267
endosome organization
4,838.15 3.27 1,316 40,292
negative regulation of neurogenesis
6,545.09 2.72 87 1,969
neuronal stem cell population maintenance
6,339.05 2.67 87 2,033
Totals 12647 139804376
No co-occurrence statistics for GO:0070695 based on MANUAL annotations
The top 45 of 45 co-occurring terms
Co-occurring Term PR S% #Together #Compared
FHF complex
26,912.48 100.00 48 48
protein localization to perinuclear region of cytoplasm
17,178.18 46.15 30 47
early endosome to late endosome transport
4,714.59 17.52 48 274
lysosome organization
2,410.07 8.96 48 536
endosome to lysosome transport
2,037.54 7.57 48 634
interkinetic nuclear migration
2,725.31 6.72 8 79
dynactin binding
1,755.16 5.08 9 138
endosome organization
1,302.22 4.84 48 992
manchette assembly
2,503.49 4.60 4 43
negative regulation of neurogenesis
1,571.53 4.52 8 137
Totals 557 768563

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2019-09-12 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2019-09-12 Added RELATION part of GO:0005737 (cytoplasm)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2009-06-11 Added RELATION is a GO:0043234 (protein complex)
2009-06-11 Added RELATION is a GO:0044444 (obsolete cytoplasmic part)
2009-06-11 Added DEFINITION A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
2009-06-11 Added TERM FHF complex
Timestamp Action Category Detail
2009-06-11 Added TERM FHF complex
Timestamp Action Category Detail
2009-06-11 Added DEFINITION A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
Timestamp Action Category Detail
2019-09-12 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2019-09-12 Added RELATION part of GO:0005737 (cytoplasm)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2009-06-11 Added RELATION is a GO:0043234 (protein complex)
2009-06-11 Added RELATION is a GO:0044444 (obsolete cytoplasmic part)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
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