This term is obsolete.
See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.

GO:0071513 JSON

phosphopantothenoylcysteine decarboxylase complex

Cellular Component

Definition (GO:0071513 GONUTS page)

A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces. PMID:19915539

Comments

See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.

48,512 annotations

Ancestor Chart

Ancestor chart for GO:0071513
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0071513 phosphopantothenoylcysteine decarboxylase complex Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 5270 A0A0D1E8X3_MYCMD GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATM9 6239 A0A2K5ATM9_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATP6 6239 A0A2K5ATP6_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0071513 based on ALL annotations
The top 100 of 142 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphopantothenoylcysteine decarboxylase complex
4,085.58 100.00 48,501 48,501
phosphopantothenoylcysteine decarboxylase activity
4,026.23 98.55 48,501 49,216
pantothenate catabolic process
4,043.40 75.10 36,711 37,094
phosphopantothenate--cysteine ligase activity
3,968.03 74.33 36,860 37,952
coenzyme A biosynthetic process
914.88 22.39 48,501 216,592
FMN binding
257.37 6.30 48,501 769,929
carboxy-lyase activity
218.52 5.26 36,397 680,500
ligase activity
48.48 1.18 36,417 3,069,286
catalytic activity
42.27 1.03 48,165 4,655,290
metal ion binding
6.40 0.16 34,102 21,769,638
Totals 425717 141181252
No co-occurrence statistics for GO:0071513 based on MANUAL annotations
The top 21 of 21 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphopantothenoylcysteine decarboxylase complex
6,474.92 100.00 218 218
phosphopantothenoylcysteine decarboxylase activity
6,358.26 98.20 218 222
coenzyme A biosynthetic process
1,354.64 20.92 218 1,042
FMN binding
1,238.19 19.12 218 1,140
CoA-synthesizing protein complex
3,237.46 1.36 3 6
phosphopantothenate--cysteine ligase activity
95.22 0.57 2 136
protein homotrimerization
46.58 0.28 1 139
intracellular monoatomic cation homeostasis
24.81 0.21 1 261
protein serine/threonine phosphatase inhibitor activity
21.23 0.19 1 305
regulation of cell growth
17.59 0.17 1 368
Totals 908 774740

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2019-09-12 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2019-09-12 Added RELATION part of GO:0005737 (cytoplasm)
2015-06-18 Added RELATION capable of GO:0004633 (phosphopantothenoylcysteine decarboxylase activity)
2013-11-15 Deleted RELATION is a GO:0043234 (protein complex)
2013-11-15 Added RELATION is a GO:1902494 (catalytic complex)
2010-01-07 Added RELATION is a GO:0044444 (obsolete cytoplasmic part)
2010-01-07 Added TERM phosphopantothenoylcysteine decarboxylase complex
2010-01-07 Added DEFINITION A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.
2010-01-07 Added RELATION is a GO:0043234 (protein complex)
Timestamp Action Category Detail
2010-01-07 Added TERM phosphopantothenoylcysteine decarboxylase complex
Timestamp Action Category Detail
2010-01-07 Added DEFINITION A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.
Timestamp Action Category Detail
2019-09-12 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2019-09-12 Added RELATION part of GO:0005737 (cytoplasm)
2015-06-18 Added RELATION capable of GO:0004633 (phosphopantothenoylcysteine decarboxylase activity)
2013-11-15 Deleted RELATION is a GO:0043234 (protein complex)
2013-11-15 Added RELATION is a GO:1902494 (catalytic complex)
2010-01-07 Added RELATION is a GO:0044444 (obsolete cytoplasmic part)
2010-01-07 Added RELATION is a GO:0043234 (protein complex)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
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