See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.
GO:0071513
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phosphopantothenoylcysteine decarboxylase complex
Cellular Component
Definition (GO:0071513 GONUTS page)
A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces. PMID:19915539
Comments
See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0071513 | phosphopantothenoylcysteine decarboxylase complex | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0D1E8X3 | 237631 | A0A0D1E8X3_USTMA | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A0G2JZ79 | 10116 | SIR1_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1L8G9S0 | 8355 | A0A1L8G9S0_XENLA | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4L3K3 | 6945 | A0A1S4L3K3_IXOSC | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A2K5ATM2 | 6239 | A0A2K5ATM2_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5ATM9 | 6239 | A0A2K5ATM9_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5ATP6 | 6239 | A0A2K5ATP6_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0071513 based on ALL annotations
The top 100 of 145 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphopantothenoylcysteine decarboxylase complex
|
4,086.68 | 100.00 | 47,701 | 47,701 |
phosphopantothenoylcysteine decarboxylase activity
|
4,026.16 | 98.52 | 47,701 | 48,418 |
pantothenate catabolic process
|
4,043.94 | 75.36 | 36,234 | 36,617 |
phosphopantothenate--cysteine ligase activity
|
3,968.13 | 74.58 | 36,384 | 37,471 |
coenzyme A biosynthetic process
|
914.24 | 22.37 | 47,701 | 213,224 |
FMN binding
|
258.61 | 6.33 | 47,701 | 753,797 |
carboxy-lyase activity
|
220.52 | 5.30 | 35,922 | 665,708 |
ligase activity
|
47.94 | 1.17 | 35,942 | 3,064,099 |
catalytic activity
|
43.04 | 1.05 | 47,375 | 4,498,570 |
metal ion binding
|
5.80 | 0.14 | 33,752 | 23,771,070 |
Totals | 419432 | 137899620 |
No co-occurrence statistics for GO:0071513 based on MANUAL annotations
The top 25 of 25 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphopantothenoylcysteine decarboxylase complex
|
6,363.54 | 100.00 | 203 | 203 |
phosphopantothenoylcysteine decarboxylase activity
|
6,240.58 | 98.07 | 203 | 207 |
coenzyme A biosynthetic process
|
1,368.43 | 21.50 | 203 | 944 |
FMN binding
|
1,211.82 | 19.04 | 203 | 1,066 |
CoA-synthesizing protein complex
|
3,181.77 | 1.46 | 3 | 6 |
phosphopantothenate--cysteine ligase activity
|
99.43 | 0.61 | 2 | 128 |
protein homotrimerization
|
43.29 | 0.29 | 1 | 147 |
intracellular monoatomic cation homeostasis
|
28.16 | 0.23 | 1 | 226 |
protein serine/threonine phosphatase inhibitor activity
|
22.49 | 0.21 | 1 | 283 |
regulation of cell growth
|
17.53 | 0.18 | 1 | 363 |
Totals | 853 | 746007 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2019-09-12 | Added | RELATION | part of GO:0005737 (cytoplasm) |
2019-09-12 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2015-06-18 | Added | RELATION | capable of GO:0004633 (phosphopantothenoylcysteine decarboxylase activity) |
2013-11-15 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2013-11-15 | Added | RELATION | is a GO:1902494 (catalytic complex) |
2010-01-07 | Added | TERM | phosphopantothenoylcysteine decarboxylase complex |
2010-01-07 | Added | DEFINITION | A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces. |
2010-01-07 | Added | RELATION | is a GO:0043234 (protein complex) |
2010-01-07 | Added | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-01-07 | Added | TERM | phosphopantothenoylcysteine decarboxylase complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-01-07 | Added | DEFINITION | A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-09-12 | Added | RELATION | part of GO:0005737 (cytoplasm) |
2019-09-12 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2015-06-18 | Added | RELATION | capable of GO:0004633 (phosphopantothenoylcysteine decarboxylase activity) |
2013-11-15 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2013-11-15 | Added | RELATION | is a GO:1902494 (catalytic complex) |
2010-01-07 | Added | RELATION | is a GO:0043234 (protein complex) |
2010-01-07 | Added | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
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