This term is obsolete.
See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.

GO:0071513 JSON

phosphopantothenoylcysteine decarboxylase complex

Cellular Component

Definition (GO:0071513 GONUTS page)

A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces. PMID:19915539

Comments

See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.

47,709 annotations

Ancestor Chart

Ancestor chart for GO:0071513
Chart options
Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0071513 phosphopantothenoylcysteine decarboxylase complex Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 237631 A0A0D1E8X3_USTMA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATM9 6239 A0A2K5ATM9_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATP6 6239 A0A2K5ATP6_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0071513 based on ALL annotations
The top 100 of 145 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphopantothenoylcysteine decarboxylase complex
4,086.68 100.00 47,701 47,701
phosphopantothenoylcysteine decarboxylase activity
4,026.16 98.52 47,701 48,418
pantothenate catabolic process
4,043.94 75.36 36,234 36,617
phosphopantothenate--cysteine ligase activity
3,968.13 74.58 36,384 37,471
coenzyme A biosynthetic process
914.24 22.37 47,701 213,224
FMN binding
258.61 6.33 47,701 753,797
carboxy-lyase activity
220.52 5.30 35,922 665,708
ligase activity
47.94 1.17 35,942 3,064,099
catalytic activity
43.04 1.05 47,375 4,498,570
metal ion binding
5.80 0.14 33,752 23,771,070
Totals 419432 137899620
No co-occurrence statistics for GO:0071513 based on MANUAL annotations
The top 25 of 25 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphopantothenoylcysteine decarboxylase complex
6,363.54 100.00 203 203
phosphopantothenoylcysteine decarboxylase activity
6,240.58 98.07 203 207
coenzyme A biosynthetic process
1,368.43 21.50 203 944
FMN binding
1,211.82 19.04 203 1,066
CoA-synthesizing protein complex
3,181.77 1.46 3 6
phosphopantothenate--cysteine ligase activity
99.43 0.61 2 128
protein homotrimerization
43.29 0.29 1 147
intracellular monoatomic cation homeostasis
28.16 0.23 1 226
protein serine/threonine phosphatase inhibitor activity
22.49 0.21 1 283
regulation of cell growth
17.53 0.18 1 363
Totals 853 746007

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2019-09-12 Added RELATION part of GO:0005737 (cytoplasm)
2019-09-12 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2015-06-18 Added RELATION capable of GO:0004633 (phosphopantothenoylcysteine decarboxylase activity)
2013-11-15 Deleted RELATION is a GO:0043234 (protein complex)
2013-11-15 Added RELATION is a GO:1902494 (catalytic complex)
2010-01-07 Added TERM phosphopantothenoylcysteine decarboxylase complex
2010-01-07 Added DEFINITION A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.
2010-01-07 Added RELATION is a GO:0043234 (protein complex)
2010-01-07 Added RELATION is a GO:0044444 (obsolete cytoplasmic part)
Timestamp Action Category Detail
2010-01-07 Added TERM phosphopantothenoylcysteine decarboxylase complex
Timestamp Action Category Detail
2010-01-07 Added DEFINITION A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.
Timestamp Action Category Detail
2019-09-12 Added RELATION part of GO:0005737 (cytoplasm)
2019-09-12 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2015-06-18 Added RELATION capable of GO:0004633 (phosphopantothenoylcysteine decarboxylase activity)
2013-11-15 Deleted RELATION is a GO:0043234 (protein complex)
2013-11-15 Added RELATION is a GO:1902494 (catalytic complex)
2010-01-07 Added RELATION is a GO:0043234 (protein complex)
2010-01-07 Added RELATION is a GO:0044444 (obsolete cytoplasmic part)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
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