GO:0071820
JSON
N-box binding
Molecular Function
Definition (GO:0071820 GONUTS page)
Binding to an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. PMID:11498047
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
N-box promoter binding | exact |
N box binding | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Considerations when annotating from ChiP assay results | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | P40999 | 284812 | PMT1M_SCHPO | GO:0003677 | To remove over-annotation from InterPro entries IPR001525 and IPR018117; for this particular C5-methyltransferase family member, there is a Ser residue in the active site that may be responsible. Reported by InterPro on 19-10-2012 | |
NOT-qualified manual | protein | A0A0G2JVM9 | 10116 | A0A0G2JVM9_RAT | GO:0000978 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A0G2K0G0 | 10116 | A0A0G2K0G0_RAT | GO:0003677 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K6Q9 | 10116 | A0A0G2K6Q9_RAT | GO:0003690 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GWQ8 | 10116 | A0A1B0GWQ8_RAT | GO:0003677 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1D8PIK2 | 237561 | A0A1D8PIK2_CANAL | GO:0000976 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:20008550 | |
NOT-qualified manual | protein | A0A287AGK9 | 9823 | A0A287AGK9_PIG | GO:0000978 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2I2ZSU6 | 9595 | A0A2I2ZSU6_GORGO | GO:0000978 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A337SMT8 | 9685 | A0A337SMT8_FELCA | GO:0000978 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A3Q2H1G8 | 9796 | A0A3Q2H1G8_HORSE | GO:0000978 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0071820 based on ALL annotations
The top 100 of 143 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
N-box binding
|
2,073,816.90 | 100.00 | 94 | 94 |
negative regulation of stomach neuroendocrine cell differentiation
|
2,073,816.90 | 96.81 | 91 | 91 |
renal interstitial fibroblast development
|
2,073,816.90 | 96.81 | 91 | 91 |
negative regulation of cell fate determination
|
2,073,816.90 | 96.81 | 91 | 91 |
trochlear nerve development
|
1,965,805.60 | 91.92 | 91 | 96 |
positive regulation of mitotic cell cycle, embryonic
|
1,357,678.60 | 64.08 | 91 | 139 |
negative regulation of pancreatic A cell differentiation
|
1,328,995.20 | 62.76 | 91 | 142 |
negative regulation of inner ear receptor cell differentiation
|
1,179,483.40 | 55.83 | 91 | 160 |
stomach neuroendocrine cell differentiation
|
1,103,610.10 | 52.30 | 91 | 171 |
negative regulation of pro-B cell differentiation
|
1,020,621.90 | 49.21 | 94 | 191 |
Totals | 8045 | 492912 |
No co-occurrence statistics for GO:0071820 based on MANUAL annotations
The top 100 of 138 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
N-box binding
|
117,436.27 | 100.00 | 11 | 11 |
negative regulation of forebrain neuron differentiation
|
52,193.90 | 25.00 | 4 | 9 |
negative regulation of pro-B cell differentiation
|
42,704.10 | 22.22 | 4 | 11 |
negative regulation of stomach neuroendocrine cell differentiation
|
117,436.27 | 18.18 | 2 | 2 |
renal interstitial fibroblast development
|
117,436.27 | 18.18 | 2 | 2 |
negative regulation of cell fate determination
|
117,436.27 | 18.18 | 2 | 2 |
stomach neuroendocrine cell differentiation
|
58,718.14 | 15.38 | 2 | 4 |
negative regulation of pancreatic A cell differentiation
|
58,718.14 | 15.38 | 2 | 4 |
negative regulation of inner ear receptor cell differentiation
|
58,718.14 | 15.38 | 2 | 4 |
ascending aorta morphogenesis
|
27,100.68 | 14.29 | 3 | 13 |
Totals | 275 | 16080 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. |
2021-05-24 | Added | DEFINITION | Binding to an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. |
2017-11-25 | Deleted | RELATION | is a GO:0000976 (transcription cis-regulatory region binding) |
2017-11-25 | Added | RELATION | is a GO:0000978 (RNA polymerase II cis-regulatory region sequence-specific DNA binding) |
2017-11-03 | Deleted | RELATION | is a GO:0044212 (transcription regulatory region DNA binding) |
2017-11-03 | Added | RELATION | is a GO:0000976 (transcription cis-regulatory region binding) |
2011-05-13 | Deleted | RELATION | is a GO:0010843 (obsolete promoter binding) |
2011-05-13 | Added | RELATION | is a GO:0044212 (transcription regulatory region DNA binding) |
2010-09-09 | Added | RELATION | is a GO:0010843 (obsolete promoter binding) |
2010-09-09 | Added | SYNONYM | N box binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-09-09 | Added | TERM | N-box binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. |
2021-05-24 | Added | DEFINITION | Binding to an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. |
2010-09-09 | Added | SYNONYM | N box binding |
2010-09-09 | Added | SYNONYM | N-box promoter binding |
2010-09-09 | Added | DEFINITION | Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-11-25 | Deleted | RELATION | is a GO:0000976 (transcription cis-regulatory region binding) |
2017-11-25 | Added | RELATION | is a GO:0000978 (RNA polymerase II cis-regulatory region sequence-specific DNA binding) |
2017-11-03 | Deleted | RELATION | is a GO:0044212 (transcription regulatory region DNA binding) |
2017-11-03 | Added | RELATION | is a GO:0000976 (transcription cis-regulatory region binding) |
2011-05-13 | Deleted | RELATION | is a GO:0010843 (obsolete promoter binding) |
2011-05-13 | Added | RELATION | is a GO:0044212 (transcription regulatory region DNA binding) |
2010-09-09 | Added | RELATION | is a GO:0010843 (obsolete promoter binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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