GO:0071878
JSON
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process
Definition (GO:0071878 GONUTS page)
Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
negative regulation of adrenergic receptor signaling pathway | exact |
negative regulation of adrenergic receptor signalling pathway | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0071878
Child Term | Relationship to GO:0071878 |
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negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
|
is_a |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
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signalling | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P13945 | 9606 | ADRB3_HUMAN | GO:0045744 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15123695 | |
NOT-qualified manual | protein | P26255 | 10116 | ADRB3_RAT | GO:0045744 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0030822 | obsolete positive regulation of cAMP catabolic process | consider GO:0071878 |
GO:0140194 | obsolete negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process | consider GO:0071878 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0071878 based on ALL annotations
The top 100 of 176 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway
|
506,334.53 | 100.00 | 385 | 385 |
cellular response to epinephrine stimulus
|
173,656.16 | 24.52 | 178 | 519 |
negative regulation of citrulline biosynthetic process
|
506,334.53 | 24.16 | 93 | 93 |
negative regulation of the force of heart contraction
|
506,334.53 | 24.16 | 93 | 93 |
nitric-oxide synthase inhibitor activity
|
500,947.97 | 24.09 | 93 | 94 |
negative regulation of arginine catabolic process
|
457,175.80 | 23.54 | 93 | 103 |
response to hydrostatic pressure
|
432,010.20 | 23.19 | 93 | 109 |
negative regulation of heat generation
|
506,334.50 | 22.60 | 87 | 87 |
negative regulation of relaxation of cardiac muscle
|
489,073.10 | 21.91 | 85 | 88 |
negative regulation of locomotion involved in locomotory behavior
|
333,720.47 | 20.23 | 87 | 132 |
Totals | 6967 | 1293424 |
No co-occurrence statistics for GO:0071878 based on MANUAL annotations
The top 100 of 153 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway
|
49,684.58 | 100.00 | 26 | 26 |
cAMP response element binding protein binding
|
9,694.55 | 17.39 | 16 | 82 |
negative regulation of relaxation of cardiac muscle
|
24,842.29 | 10.34 | 3 | 6 |
cellular response to epinephrine stimulus
|
8,013.64 | 9.62 | 5 | 31 |
negative regulation of citrulline biosynthetic process
|
49,684.58 | 7.69 | 2 | 2 |
negative regulation of the force of heart contraction
|
49,684.58 | 7.69 | 2 | 2 |
negative regulation of heat generation
|
49,684.58 | 7.69 | 2 | 2 |
nitric-oxide synthase inhibitor activity
|
33,123.06 | 7.41 | 2 | 3 |
negative regulation of cellular response to vascular endothelial growth factor stimulus
|
24,842.29 | 7.14 | 2 | 4 |
beta-3 adrenergic receptor binding
|
19,873.83 | 6.90 | 2 | 5 |
Totals | 252 | 28848 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-08-13 | Deleted | SYNONYM | false |
2021-08-13 | Added | SYNONYM | negative regulation of adrenergic receptor signaling pathway |
2018-02-18 | Deleted | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. |
2018-02-18 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. |
2018-02-18 | Added | SYNONYM | false |
2018-02-18 | Added | RELATION | negatively regulates GO:0071880 (adenylate cyclase-activating adrenergic receptor signaling pathway) |
2018-02-18 | Deleted | RELATION | is a GO:0071877 (regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway) |
2018-02-18 | Deleted | RELATION | negatively regulates GO:0071875 (adrenergic receptor signaling pathway) |
2018-02-18 | Added | RELATION | is a GO:0106072 (negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) |
2018-02-18 | Deleted | RELATION | is a GO:0045744 (negative regulation of G protein-coupled receptor signaling pathway) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-02-18 | Updated | TERM | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway |
2010-09-15 | Added | TERM | negative regulation of adrenergic receptor signaling pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-08-13 | Deleted | SYNONYM | false |
2021-08-13 | Added | SYNONYM | negative regulation of adrenergic receptor signaling pathway |
2018-02-18 | Deleted | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. |
2018-02-18 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. |
2018-02-18 | Added | SYNONYM | false |
2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. |
2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. |
2010-09-15 | Added | SYNONYM | negative regulation of adrenergic receptor signalling pathway |
2010-09-15 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-02-18 | Added | RELATION | negatively regulates GO:0071880 (adenylate cyclase-activating adrenergic receptor signaling pathway) |
2018-02-18 | Deleted | RELATION | is a GO:0071877 (regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway) |
2018-02-18 | Deleted | RELATION | negatively regulates GO:0071875 (adrenergic receptor signaling pathway) |
2018-02-18 | Added | RELATION | is a GO:0106072 (negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) |
2018-02-18 | Deleted | RELATION | is a GO:0045744 (negative regulation of G protein-coupled receptor signaling pathway) |
2010-09-15 | Added | RELATION | is a GO:0045744 (negative regulation of G protein-coupled receptor signaling pathway) |
2010-09-15 | Added | RELATION | is a GO:0071877 (regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway) |
2010-09-15 | Added | RELATION | negatively regulates GO:0071875 (adrenergic receptor signaling pathway) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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