This term is obsolete.

GO:0072538 JSON

T-helper 17 type immune response

Biological Process

Definition (GO:0072538 GONUTS page)

An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.

Acknowledgement

This term was created by the GO Consortium with support from: BHF image

1,503 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
Th17 immune response exact

Ancestor Chart

Ancestor chart for GO:0072538
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0072538

Child Term Relationship to
GO:0072538
negative regulation of T-helper 17 type immune response
negatively_regulates
T-helper 17 cell differentiation
part_of
regulation of T-helper 17 type immune response
regulates
positive regulation of T-helper 17 type immune response
positively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0072538 T-helper 17 type immune response Only in Taxon 33208 Metazoa

More information on taxon constraints in GO is available here

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CL CL:0000899 T-helper 17 cell

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0072538 based on ALL annotations
The top 100 of 435 co-occurring terms
Co-occurring Term PR S% #Together #Compared
T-helper 17 type immune response
531,168.30 100.00 367 367
RNA sequestering activity
476,562.22 25.40 96 107
coronary sinus valve morphogenesis
531,168.30 23.16 85 85
Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation
531,168.30 23.16 85 85
venous endothelial cell differentiation
531,168.30 23.16 85 85
coronary vein morphogenesis
518,957.60 23.04 85 87
cellular response to interleukin-17
153,881.23 21.45 166 573
interleukin-17-mediated signaling pathway
135,244.72 20.71 193 758
growth involved in heart morphogenesis
327,168.90 20.24 85 138
foregut morphogenesis
309,241.84 19.86 85 146
Totals 8926 43676
No co-occurrence statistics for GO:0072538 based on MANUAL annotations
The top 100 of 418 co-occurring terms
Co-occurring Term PR S% #Together #Compared
T-helper 17 type immune response
40,368.72 100.00 32 32
interleukin-17-mediated signaling pathway
13,163.71 23.81 15 46
transitional two stage B cell differentiation
40,368.72 18.75 6 6
eosinophil mediated immunity
40,368.72 18.75 6 6
interleukin-17A-mediated signaling pathway
16,147.49 18.18 8 20
protein localization to P-body
17,300.88 15.00 6 14
B cell affinity maturation
16,147.49 14.63 6 15
leukocyte activation involved in inflammatory response
15,138.27 14.29 6 16
eosinophil homeostasis
14,247.78 13.95 6 17
cellular response to interleukin-17
8,970.83 13.33 8 36
Totals 390 3649

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2011-01-19 Added TERM T-helper 17 type immune response
2011-01-19 Added SYNONYM Th17 immune response
2011-01-19 Added RELATION is a GO:0002460 (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains)
2011-01-19 Added DEFINITION An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.
Timestamp Action Category Detail
2011-01-19 Added TERM T-helper 17 type immune response
Timestamp Action Category Detail
2011-01-19 Added SYNONYM Th17 immune response
2011-01-19 Added DEFINITION An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.
Timestamp Action Category Detail
2011-01-19 Added RELATION is a GO:0002460 (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
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