GO:0072538
JSON
T-helper 17 type immune response
Biological Process
Definition (GO:0072538 GONUTS page)
An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Th17 immune response | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0072538
Child Term | Relationship to GO:0072538 |
---|---|
negative regulation of T-helper 17 type immune response
|
negatively_regulates |
T-helper 17 cell differentiation
|
part_of |
regulation of T-helper 17 type immune response
|
regulates |
positive regulation of T-helper 17 type immune response
|
positively_regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0072538 | T-helper 17 type immune response | Only in Taxon | 33208 | Metazoa |
More information on taxon constraints in GO is available here
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CL | CL:0000899 | T-helper 17 cell |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0072538 based on ALL annotations
The top 100 of 435 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
T-helper 17 type immune response
|
531,168.30 | 100.00 | 367 | 367 |
RNA sequestering activity
|
476,562.22 | 25.40 | 96 | 107 |
coronary sinus valve morphogenesis
|
531,168.30 | 23.16 | 85 | 85 |
Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation
|
531,168.30 | 23.16 | 85 | 85 |
venous endothelial cell differentiation
|
531,168.30 | 23.16 | 85 | 85 |
coronary vein morphogenesis
|
518,957.60 | 23.04 | 85 | 87 |
cellular response to interleukin-17
|
153,881.23 | 21.45 | 166 | 573 |
interleukin-17-mediated signaling pathway
|
135,244.72 | 20.71 | 193 | 758 |
growth involved in heart morphogenesis
|
327,168.90 | 20.24 | 85 | 138 |
foregut morphogenesis
|
309,241.84 | 19.86 | 85 | 146 |
Totals | 8926 | 43676 |
No co-occurrence statistics for GO:0072538 based on MANUAL annotations
The top 100 of 418 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
T-helper 17 type immune response
|
40,368.72 | 100.00 | 32 | 32 |
interleukin-17-mediated signaling pathway
|
13,163.71 | 23.81 | 15 | 46 |
transitional two stage B cell differentiation
|
40,368.72 | 18.75 | 6 | 6 |
eosinophil mediated immunity
|
40,368.72 | 18.75 | 6 | 6 |
interleukin-17A-mediated signaling pathway
|
16,147.49 | 18.18 | 8 | 20 |
protein localization to P-body
|
17,300.88 | 15.00 | 6 | 14 |
B cell affinity maturation
|
16,147.49 | 14.63 | 6 | 15 |
leukocyte activation involved in inflammatory response
|
15,138.27 | 14.29 | 6 | 16 |
eosinophil homeostasis
|
14,247.78 | 13.95 | 6 | 17 |
cellular response to interleukin-17
|
8,970.83 | 13.33 | 8 | 36 |
Totals | 390 | 3649 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
2011-01-19 | Added | TERM | T-helper 17 type immune response |
2011-01-19 | Added | SYNONYM | Th17 immune response |
2011-01-19 | Added | RELATION | is a GO:0002460 (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) |
2011-01-19 | Added | DEFINITION | An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-01-19 | Added | TERM | T-helper 17 type immune response |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-01-19 | Added | SYNONYM | Th17 immune response |
2011-01-19 | Added | DEFINITION | An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-01-19 | Added | RELATION | is a GO:0002460 (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
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