GO:0080109
JSON
indole-3-acetonitrile nitrile hydratase activity
Molecular Function
Definition (GO:0080109 GONUTS page)
Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide. PMID:11607511 PMID:12430025
Ancestor Chart
Ancestor chart for GO:0080109
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Annotating to catalytic activities using the IPI evidence code | Link |
| Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
| NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
| NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
| NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
| Database | ID | Description |
|---|---|---|
| KEGG_REACTION | R04020 | |
| MetaCyc | RXN-7567 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0080109 based on ALL annotations
The top 22 of 22 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
indole-3-acetonitrile nitrile hydratase activity
|
71,977.80 | 100.00 | 2,753 | 2,753 |
|
nitrile hydratase activity
|
20,520.31 | 28.50 | 2,750 | 9,646 |
|
transition metal ion binding
|
1,010.11 | 1.40 | 2,748 | 195,815 |
|
indole-3-acetonitrile nitrilase activity
|
35,988.90 | 0.18 | 5 | 10 |
|
indoleacetic acid biosynthetic process
|
3,199.01 | 0.07 | 2 | 45 |
|
cellular response to sulfate starvation
|
841.85 | 0.07 | 2 | 171 |
|
cyanoalanine nitrilase activity
|
269.58 | 0.06 | 2 | 534 |
|
lyase activity
|
43.73 | 0.06 | 2,748 | 4,523,172 |
|
detoxification of nitrogen compound
|
59.53 | 0.04 | 2 | 2,418 |
|
glucosinolate catabolic process
|
94.09 | 0.03 | 1 | 765 |
| Totals | 11046 | 82713373 | ||
No co-occurrence statistics for GO:0080109 based on MANUAL annotations
The top 12 of 12 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
indole-3-acetonitrile nitrile hydratase activity
|
470,511.00 | 100.00 | 3 | 3 |
|
indole-3-acetonitrile nitrilase activity
|
352,883.25 | 75.00 | 3 | 4 |
|
indoleacetic acid biosynthetic process
|
85,547.46 | 16.67 | 2 | 11 |
|
nitrilase activity
|
12,491.44 | 2.65 | 3 | 113 |
|
cellular response to sulfate starvation
|
5,535.42 | 1.15 | 1 | 85 |
|
glucosinolate catabolic process
|
5,170.45 | 1.08 | 1 | 91 |
|
apoplast
|
928.03 | 0.20 | 1 | 507 |
|
plasmodesma
|
159.28 | 0.03 | 1 | 2,954 |
|
chloroplast
|
41.75 | 0.01 | 1 | 11,269 |
|
mRNA binding
|
36.37 | 0.01 | 2 | 25,874 |
| Totals | 23 | 172324 | ||
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-09-02 | Deleted | XREF | EC:4.2.1.84 |
| 2019-06-20 | Added | XREF | KEGG_REACTION:R04020 |
| 2019-06-20 | Deleted | XREF | KEGG:R04020 |
| 2011-08-28 | Added | XREF | EC:4.2.1.84 |
| 2011-08-28 | Added | XREF | MetaCyc:RXN-7567 |
| 2011-08-28 | Added | XREF | KEGG:R04020 |
| 2010-09-15 | Added | DEFINITION | Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide. |
| 2010-09-15 | Deleted | DEFINITION | Catalysis of the reaction: indole-3-acetonitrile (IAN) + H2O = indole-3-acetamide (IAM). |
| 2009-04-29 | Added | DEFINITION | Catalysis of the reaction: indole-3-acetonitrile (IAN) + H2O = indole-3-acetamide (IAM). |
| 2009-04-29 | Added | TERM | indole-3-acetonitrile nitrile hydratase activity |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-04-29 | Added | TERM | indole-3-acetonitrile nitrile hydratase activity |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2010-09-15 | Added | DEFINITION | Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide. |
| 2010-09-15 | Deleted | DEFINITION | Catalysis of the reaction: indole-3-acetonitrile (IAN) + H2O = indole-3-acetamide (IAM). |
| 2009-04-29 | Added | DEFINITION | Catalysis of the reaction: indole-3-acetonitrile (IAN) + H2O = indole-3-acetamide (IAM). |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-04-29 | Added | RELATION | is a GO:0018822 (nitrile hydratase activity) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-09-02 | Deleted | XREF | EC:4.2.1.84 |
| 2019-06-20 | Added | XREF | KEGG_REACTION:R04020 |
| 2019-06-20 | Deleted | XREF | KEGG:R04020 |
| 2011-08-28 | Added | XREF | EC:4.2.1.84 |
| 2011-08-28 | Added | XREF | MetaCyc:RXN-7567 |
| 2011-08-28 | Added | XREF | KEGG:R04020 |
| Timestamp | Action | Category | Detail |
|---|
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