This term is obsolete.

GO:0090611 JSON

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

Biological Process

Definition (GO:0090611 GONUTS page)

The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. PMID:22547407

412 annotations

Ancestor Chart

Ancestor chart for GO:0090611
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Ancestor chart

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein P52708 4558 HNLS_SORBI GO:0006508 To remove over-annotation from InterPro entries. Swiss-Prot entry has been shown not to have carboxypeptidase activity (PMID: 12356304). Reported by InterPro on 15th January 2016. IPR001563|IPR018202
IEA Review protein Q18581 6239 ACN1_CAEEL GO:0006508 To remove over-annotation from InterPro entries; Eukaryotic TrEmbl proteins are false positives probably due to low quality sequences. Reported by InterPro on 17th April 2015. IPR001548
NOT-qualified manual protein A0A0B4LEH6 7227 A0A0B4LEH6_DROME GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10913309
NOT-qualified manual protein A0A139WBK0 7070 A0A139WBK0_TRICA GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1D8PJK3 237561 A0A1D8PJK3_CANAL GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4GA36 7165 A0A1S4GA36_ANOGA GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2A6CPC3 54126 A0A2A6CPC3_PRIPA GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2A6CQR6 54126 A0A2A6CQR6_PRIPA GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A5F5PED9 9796 A0A5F5PED9_HORSE GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A8I3PJW4 9615 A0A8I3PJW4_CANLF GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0090611 based on ALL annotations
The top 100 of 140 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
482,128.60 100.00 411 411
late endosomal microautophagy
368,933.22 37.85 176 230
protein depolymerization
482,128.60 23.84 98 98
ESCRT III complex disassembly
446,081.66 23.63 99 107
vesicle uncoating
482,128.66 21.90 90 90
negative regulation of cytokinesis
127,543.73 20.28 191 722
positive regulation of exosomal secretion
94,158.94 16.60 216 1,106
midbody abscission
74,803.65 15.52 411 2,649
positive regulation of viral budding via host ESCRT complex
162,515.27 15.31 90 267
negative regulation of exosomal secretion
136,952.47 14.89 98 345
Totals 14882 4478293
No co-occurrence statistics for GO:0090611 based on MANUAL annotations
The top 100 of 128 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
100,823.79 100.00 14 14
protein depolymerization
100,823.79 28.57 4 4
late endosomal microautophagy
50,411.90 26.32 5 10
ESCRT III complex disassembly
38,778.38 22.73 5 13
viral budding via host ESCRT complex
20,164.76 20.00 14 70
positive regulation of exosomal secretion
19,672.94 17.02 8 41
negative regulation of exosomal secretion
28,806.80 16.67 4 14
viral budding from plasma membrane
16,803.97 16.22 12 72
Flemming body
15,511.35 14.49 10 65
vesicle uncoating
100,823.79 14.29 2 2
Totals 493 57537

Change Log

Timestamp Action Category Detail
2022-11-22 Added DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
2022-11-22 Deleted DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
2014-10-25 Added TERM ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
2014-10-25 Added DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
2014-10-25 Added RELATION is a GO:0051603 (proteolysis involved in protein catabolic process)
Timestamp Action Category Detail
2014-10-25 Added TERM ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
Timestamp Action Category Detail
2022-11-22 Added DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
2022-11-22 Deleted DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
2014-10-25 Added DEFINITION The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
Timestamp Action Category Detail
2014-10-25 Added RELATION is a GO:0051603 (proteolysis involved in protein catabolic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
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