GO:0090611
JSON
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
Biological Process
Definition (GO:0090611 GONUTS page)
The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. PMID:22547407
Ancestor Chart
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | P52708 | 4558 | HNLS_SORBI | GO:0006508 | To remove over-annotation from InterPro entries. Swiss-Prot entry has been shown not to have carboxypeptidase activity (PMID: 12356304). Reported by InterPro on 15th January 2016. | IPR001563|IPR018202 |
IEA Review | protein | Q18581 | 6239 | ACN1_CAEEL | GO:0006508 | To remove over-annotation from InterPro entries; Eukaryotic TrEmbl proteins are false positives probably due to low quality sequences. Reported by InterPro on 17th April 2015. | IPR001548 |
NOT-qualified manual | protein | A0A0B4LEH6 | 7227 | A0A0B4LEH6_DROME | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10913309 | |
NOT-qualified manual | protein | A0A139WBK0 | 7070 | A0A139WBK0_TRICA | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1D8PJK3 | 237561 | A0A1D8PJK3_CANAL | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4GA36 | 7165 | A0A1S4GA36_ANOGA | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2A6CPC3 | 54126 | A0A2A6CPC3_PRIPA | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2A6CQR6 | 54126 | A0A2A6CQR6_PRIPA | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A5F5PED9 | 9796 | A0A5F5PED9_HORSE | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I3PJW4 | 9615 | A0A8I3PJW4_CANLF | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0090611 based on ALL annotations
The top 100 of 140 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
|
482,128.60 | 100.00 | 411 | 411 |
late endosomal microautophagy
|
368,933.22 | 37.85 | 176 | 230 |
protein depolymerization
|
482,128.60 | 23.84 | 98 | 98 |
ESCRT III complex disassembly
|
446,081.66 | 23.63 | 99 | 107 |
vesicle uncoating
|
482,128.66 | 21.90 | 90 | 90 |
negative regulation of cytokinesis
|
127,543.73 | 20.28 | 191 | 722 |
positive regulation of exosomal secretion
|
94,158.94 | 16.60 | 216 | 1,106 |
midbody abscission
|
74,803.65 | 15.52 | 411 | 2,649 |
positive regulation of viral budding via host ESCRT complex
|
162,515.27 | 15.31 | 90 | 267 |
negative regulation of exosomal secretion
|
136,952.47 | 14.89 | 98 | 345 |
Totals | 14882 | 4478293 |
No co-occurrence statistics for GO:0090611 based on MANUAL annotations
The top 100 of 128 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
|
100,823.79 | 100.00 | 14 | 14 |
protein depolymerization
|
100,823.79 | 28.57 | 4 | 4 |
late endosomal microautophagy
|
50,411.90 | 26.32 | 5 | 10 |
ESCRT III complex disassembly
|
38,778.38 | 22.73 | 5 | 13 |
viral budding via host ESCRT complex
|
20,164.76 | 20.00 | 14 | 70 |
positive regulation of exosomal secretion
|
19,672.94 | 17.02 | 8 | 41 |
negative regulation of exosomal secretion
|
28,806.80 | 16.67 | 4 | 14 |
viral budding from plasma membrane
|
16,803.97 | 16.22 | 12 | 72 |
Flemming body
|
15,511.35 | 14.49 | 10 | 65 |
vesicle uncoating
|
100,823.79 | 14.29 | 2 | 2 |
Totals | 493 | 57537 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-22 | Added | DEFINITION | The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. |
2022-11-22 | Deleted | DEFINITION | The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. |
2014-10-25 | Added | TERM | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway |
2014-10-25 | Added | DEFINITION | The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. |
2014-10-25 | Added | RELATION | is a GO:0051603 (proteolysis involved in protein catabolic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-10-25 | Added | TERM | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-11-22 | Added | DEFINITION | The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. |
2022-11-22 | Deleted | DEFINITION | The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. |
2014-10-25 | Added | DEFINITION | The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-10-25 | Added | RELATION | is a GO:0051603 (proteolysis involved in protein catabolic process) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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