This term is obsolete.

GO:0097060 JSON

synaptic membrane

Cellular Component

Definition (GO:0097060 GONUTS page)

A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. PMID:20410104

Acknowledgement

This term was created by the GO Consortium with support from: BHF image

390,175 annotations

Ancestor Chart

Ancestor chart for GO:0097060
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0097060

Child Term Relationship to
GO:0097060
presynaptic active zone membrane
is_a
presynaptic endocytic zone membrane
is_a
extrinsic component of synaptic membrane
part_of
postsynaptic endocytic zone membrane
is_a
presynaptic periactive zone
is_a
presynaptic membrane
is_a
postsynaptic membrane
is_a
dendritic spine membrane
is_a
postsynaptic specialization membrane
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0097060 synaptic membrane Only in Taxon 33208 Metazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 5270 BI1_MYCMD GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A022QST3 4155 A0A022QST3_ERYGU GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A022S0M6 4155 A0A022S0M6_ERYGU GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059AQE2 71139 A0A059AQE2_EUCGR GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059B0U9 71139 A0A059B0U9_EUCGR GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
UniProtKB-SubCell SL-0531 Synaptic cell membrane

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0099144 obsolete anchored component of synaptic membrane replaced_by GO:0097060
GO:0099240 obsolete intrinsic component of synaptic membrane replaced_by GO:0097060
GO:0099699 obsolete integral component of synaptic membrane replaced_by GO:0097060

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0097060 based on ALL annotations
The top 100 of 2,245 co-occurring terms
Co-occurring Term PR S% #Together #Compared
synaptic membrane
21,907.67 100.00 9,045 9,045
metalloendopeptidase activity involved in amyloid precursor protein catabolic process
19,997.61 20.54 1,895 2,076
regulation of Ras protein signal transduction
9,228.52 19.49 2,407 5,714
amyloid precursor protein catabolic process
9,867.48 16.80 1,912 4,245
maintenance of centrosome location
9,781.84 15.32 1,711 3,832
regulation of Golgi organization
4,603.06 11.04 1,708 8,129
regulation of ventricular cardiac muscle cell membrane repolarization
4,126.41 10.41 1,708 9,068
protein kinase A regulatory subunit binding
2,034.96 6.64 1,711 18,420
membrane protein ectodomain proteolysis
1,778.28 6.23 1,912 23,555
potassium channel regulator activity
1,325.44 4.87 1,803 29,801
Totals 54277 1184710
No co-occurrence statistics for GO:0097060 based on MANUAL annotations
The top 100 of 1,908 co-occurring terms
Co-occurring Term PR S% #Together #Compared
synaptic membrane
3,877.84 100.00 364 364
regulation of Ras protein signal transduction
1,627.31 10.96 47 112
neuron spine
2,481.82 8.38 32 50
cGMP catabolic process
1,102.52 6.64 29 102
negative regulation of cGMP-mediated signaling
1,060.92 6.58 29 106
3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
1,022.34 6.52 29 110
metalloendopeptidase activity involved in amyloid precursor protein catabolic process
3,046.87 5.95 22 28
regulation of mitochondrion organization
551.26 5.38 29 204
maintenance of centrosome location
853.12 4.98 22 100
excitatory synapse
412.21 4.57 27 254
Totals 2044 22537

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_synapse 357

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2019-09-12 Deleted RELATION is a GO:0044456 (obsolete synapse part)
2017-04-07 Added SUBSET goslim_synapse
2016-01-20 Added RELATION part of GO:0045202 (synapse)
2015-07-11 Added RELATION is a GO:0098590 (plasma membrane region)
2015-07-11 Deleted RELATION is a GO:0044459 (obsolete plasma membrane part)
2013-10-10 Deleted RELATION is a GO:0016020 (membrane)
2013-10-10 Added RELATION is a GO:0044459 (obsolete plasma membrane part)
2011-06-09 Added DEFINITION A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
2011-06-09 Added RELATION is a GO:0016020 (membrane)
Timestamp Action Category Detail
2011-06-09 Added TERM synaptic membrane
Timestamp Action Category Detail
2011-06-09 Added DEFINITION A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
Timestamp Action Category Detail
2019-09-12 Deleted RELATION is a GO:0044456 (obsolete synapse part)
2016-01-20 Added RELATION part of GO:0045202 (synapse)
2015-07-11 Added RELATION is a GO:0098590 (plasma membrane region)
2015-07-11 Deleted RELATION is a GO:0044459 (obsolete plasma membrane part)
2013-10-10 Deleted RELATION is a GO:0016020 (membrane)
2013-10-10 Added RELATION is a GO:0044459 (obsolete plasma membrane part)
2011-06-09 Added RELATION is a GO:0016020 (membrane)
2011-06-09 Added RELATION is a GO:0044456 (obsolete synapse part)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2017-04-07 Added SUBSET goslim_synapse
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