GO:0097060
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synaptic membrane
Cellular Component
Definition (GO:0097060 GONUTS page)
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. PMID:20410104
Acknowledgement
This term was created by the GO Consortium with support from:
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0097060
Child Term | Relationship to GO:0097060 |
---|---|
postsynaptic membrane
|
is_a |
presynaptic membrane
|
is_a |
presynaptic periactive zone
|
is_a |
postsynaptic endocytic zone membrane
|
is_a |
presynaptic endocytic zone membrane
|
is_a |
presynaptic active zone membrane
|
is_a |
postsynaptic specialization membrane
|
is_a |
extrinsic component of synaptic membrane
|
part_of |
dendritic spine membrane
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0097060 | synaptic membrane | Only in Taxon | 33208 | Metazoa |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A022QST3 | 4155 | A0A022QST3_ERYGU | GO:0005886 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A022S0M6 | 4155 | A0A022S0M6_ERYGU | GO:0005886 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A059AQE2 | 71139 | A0A059AQE2_EUCGR | GO:0005886 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A059B0U9 | 71139 | A0A059B0U9_EUCGR | GO:0005886 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
UniProtKB-SubCell | SL-0531 | Synaptic cell membrane |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0099144 | obsolete anchored component of synaptic membrane | replaced_by GO:0097060 |
GO:0099240 | obsolete intrinsic component of synaptic membrane | replaced_by GO:0097060 |
GO:0099699 | obsolete integral component of synaptic membrane | replaced_by GO:0097060 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0097060 based on ALL annotations
The top 100 of 2,278 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
synaptic membrane
|
17,492.71 | 100.00 | 11,144 | 11,144 |
metalloendopeptidase activity involved in amyloid precursor protein catabolic process
|
15,945.97 | 16.48 | 1,866 | 2,047 |
regulation of Ras protein signal transduction
|
7,242.98 | 16.12 | 2,327 | 5,620 |
amyloid precursor protein catabolic process
|
7,833.24 | 13.98 | 1,883 | 4,205 |
maintenance of centrosome location
|
7,826.92 | 12.69 | 1,677 | 3,748 |
synaptic membrane adhesion
|
3,909.50 | 11.42 | 2,110 | 9,441 |
regulation of Golgi organization
|
3,691.73 | 9.62 | 1,674 | 7,932 |
regulation of ventricular cardiac muscle cell membrane repolarization
|
3,293.53 | 9.12 | 1,674 | 8,891 |
postsynaptic density protein 95 clustering
|
12,300.27 | 7.15 | 822 | 1,169 |
excitatory synapse assembly
|
11,209.45 | 7.12 | 826 | 1,289 |
Totals | 68173 | 1347816 |
No co-occurrence statistics for GO:0097060 based on MANUAL annotations
The top 100 of 1,928 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
synaptic membrane
|
4,024.30 | 100.00 | 321 | 321 |
regulation of Ras protein signal transduction
|
1,571.39 | 10.65 | 41 | 105 |
metalloendopeptidase activity involved in amyloid precursor protein catabolic process
|
3,058.46 | 5.81 | 19 | 25 |
cGMP catabolic process
|
1,017.64 | 5.70 | 22 | 87 |
negative regulation of cGMP-mediated signaling
|
941.86 | 5.60 | 22 | 94 |
negative regulation of cAMP-mediated signaling
|
941.86 | 5.60 | 22 | 94 |
3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
|
912.73 | 5.56 | 22 | 97 |
excitatory synapse
|
456.54 | 5.08 | 27 | 238 |
maintenance of centrosome location
|
804.86 | 4.58 | 18 | 90 |
regulation of mitochondrion organization
|
433.99 | 4.37 | 22 | 204 |
Totals | 1783 | 17688 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_synapse | 357 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
2019-09-12 | Deleted | RELATION | is a GO:0044456 (obsolete synapse part) |
2017-04-07 | Added | SUBSET | goslim_synapse |
2016-01-20 | Added | RELATION | part of GO:0045202 (synapse) |
2015-07-11 | Deleted | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2015-07-11 | Added | RELATION | is a GO:0098590 (plasma membrane region) |
2013-10-10 | Deleted | RELATION | is a GO:0016020 (membrane) |
2013-10-10 | Added | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2011-06-09 | Added | DEFINITION | A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. |
2011-06-09 | Added | TERM | synaptic membrane |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-06-09 | Added | TERM | synaptic membrane |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-06-09 | Added | DEFINITION | A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-09-12 | Deleted | RELATION | is a GO:0044456 (obsolete synapse part) |
2016-01-20 | Added | RELATION | part of GO:0045202 (synapse) |
2015-07-11 | Deleted | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2015-07-11 | Added | RELATION | is a GO:0098590 (plasma membrane region) |
2013-10-10 | Deleted | RELATION | is a GO:0016020 (membrane) |
2013-10-10 | Added | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2011-06-09 | Added | RELATION | is a GO:0044456 (obsolete synapse part) |
2011-06-09 | Added | RELATION | is a GO:0016020 (membrane) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
2017-04-07 | Added | SUBSET | goslim_synapse |
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