This term is obsolete.

GO:0097102 JSON

endothelial tip cell fate specification

Biological Process

Definition (GO:0097102 GONUTS page)

The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels. PMID:21521739

85 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
angiogenic tip cell fate specification exact

Ancestor Chart

Ancestor chart for GO:0097102
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0097102 endothelial tip cell fate specification Only in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I6A813 10116 A0A8I6A813_RAT GO:0002040 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GL08 10116 A0A8I6GL08_RAT GO:0002040 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A9K3Y7N3 10116 A0A9K3Y7N3_RAT GO:0002040 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein M0RA19 10116 M0RA19_RAT GO:0002040 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P17813 9606 EGLN_HUMAN GO:0002040 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q3KR75 10116 Q3KR75_RAT GO:0002040 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_specification_of CL CL:0000704 endothelial tip cell

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0097102 based on ALL annotations
The top 100 of 224 co-occurring terms
Co-occurring Term PR S% #Together #Compared
endothelial tip cell fate specification
2,348,660.00 100.00 83 83
cerebellar molecular layer formation
2,348,660.00 96.39 80 80
regulation of skeletal muscle tissue growth
2,348,660.00 96.39 80 80
negative regulation of hemocyte differentiation
1,297,511.40 53.74 79 143
Notch signaling pathway involved in arterial endothelial cell fate commitment
1,167,036.00 48.78 80 161
loop of Henle development
770,052.44 32.39 80 244
negative regulation of epidermal cell differentiation
760,699.60 32.00 80 247
cerebellar Purkinje cell layer structural organization
742,659.30 31.25 80 253
compartment pattern specification
614,028.80 25.89 80 306
positive regulation of skeletal muscle tissue growth
612,028.70 25.81 80 307
Totals 5295 608412
No co-occurrence statistics for GO:0097102 based on MANUAL annotations
The top 100 of 170 co-occurring terms
Co-occurring Term PR S% #Together #Compared
endothelial tip cell fate specification
215,299.84 100.00 6 6
cerebellar molecular layer formation
215,299.84 50.00 3 3
regulation of skeletal muscle tissue growth
215,299.84 50.00 3 3
Notch signaling pathway involved in arterial endothelial cell fate commitment
129,179.90 37.50 3 5
loop of Henle development
71,766.62 20.00 2 6
cerebellar Purkinje cell layer structural organization
53,824.96 20.00 3 12
negative regulation of epidermal cell differentiation
37,994.09 15.00 3 17
skeletal muscle tissue growth
35,883.31 14.29 3 18
inhibition of neuroepithelial cell differentiation
39,145.43 13.33 2 11
compartment pattern specification
35,883.31 12.50 2 12
Totals 204 9857

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2013-11-28 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2013-03-10 Deleted RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2012-12-21 Added RELATION is a GO:0044767 (single-organism developmental process)
2012-10-29 Added RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2011-07-31 Added RELATION part of GO:0002040 (sprouting angiogenesis)
2011-07-31 Added RELATION is a GO:0097101 (blood vessel endothelial cell fate specification)
2011-07-31 Added TERM endothelial tip cell fate specification
2011-07-31 Added DEFINITION The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.
2011-07-31 Added SYNONYM angiogenic tip cell fate specification
Timestamp Action Category Detail
2011-07-31 Added TERM endothelial tip cell fate specification
Timestamp Action Category Detail
2011-07-31 Added DEFINITION The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.
2011-07-31 Added SYNONYM angiogenic tip cell fate specification
Timestamp Action Category Detail
2013-11-28 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2013-03-10 Deleted RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2012-12-21 Added RELATION is a GO:0044767 (single-organism developmental process)
2012-10-29 Added RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2011-07-31 Added RELATION part of GO:0002040 (sprouting angiogenesis)
2011-07-31 Added RELATION is a GO:0097101 (blood vessel endothelial cell fate specification)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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