GO:0097102
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endothelial tip cell fate specification
Biological Process
Definition (GO:0097102 GONUTS page)
The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels. PMID:21521739
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
angiogenic tip cell fate specification | exact |
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0097102 | endothelial tip cell fate specification | Only in Taxon | 7742 | Vertebrata |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I6A813 | 10116 | A0A8I6A813_RAT | GO:0002040 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6GL08 | 10116 | A0A8I6GL08_RAT | GO:0002040 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A9K3Y7N3 | 10116 | A0A9K3Y7N3_RAT | GO:0002040 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | M0RA19 | 10116 | M0RA19_RAT | GO:0002040 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P17813 | 9606 | EGLN_HUMAN | GO:0002040 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q3KR75 | 10116 | Q3KR75_RAT | GO:0002040 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
results_in_specification_of | CL | CL:0000704 | endothelial tip cell |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0097102 based on ALL annotations
The top 100 of 224 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
endothelial tip cell fate specification
|
2,348,660.00 | 100.00 | 83 | 83 |
cerebellar molecular layer formation
|
2,348,660.00 | 96.39 | 80 | 80 |
regulation of skeletal muscle tissue growth
|
2,348,660.00 | 96.39 | 80 | 80 |
negative regulation of hemocyte differentiation
|
1,297,511.40 | 53.74 | 79 | 143 |
Notch signaling pathway involved in arterial endothelial cell fate commitment
|
1,167,036.00 | 48.78 | 80 | 161 |
loop of Henle development
|
770,052.44 | 32.39 | 80 | 244 |
negative regulation of epidermal cell differentiation
|
760,699.60 | 32.00 | 80 | 247 |
cerebellar Purkinje cell layer structural organization
|
742,659.30 | 31.25 | 80 | 253 |
compartment pattern specification
|
614,028.80 | 25.89 | 80 | 306 |
positive regulation of skeletal muscle tissue growth
|
612,028.70 | 25.81 | 80 | 307 |
Totals | 5295 | 608412 |
No co-occurrence statistics for GO:0097102 based on MANUAL annotations
The top 100 of 170 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
endothelial tip cell fate specification
|
215,299.84 | 100.00 | 6 | 6 |
cerebellar molecular layer formation
|
215,299.84 | 50.00 | 3 | 3 |
regulation of skeletal muscle tissue growth
|
215,299.84 | 50.00 | 3 | 3 |
Notch signaling pathway involved in arterial endothelial cell fate commitment
|
129,179.90 | 37.50 | 3 | 5 |
loop of Henle development
|
71,766.62 | 20.00 | 2 | 6 |
cerebellar Purkinje cell layer structural organization
|
53,824.96 | 20.00 | 3 | 12 |
negative regulation of epidermal cell differentiation
|
37,994.09 | 15.00 | 3 | 17 |
skeletal muscle tissue growth
|
35,883.31 | 14.29 | 3 | 18 |
inhibition of neuroepithelial cell differentiation
|
39,145.43 | 13.33 | 2 | 11 |
compartment pattern specification
|
35,883.31 | 12.50 | 2 | 12 |
Totals | 204 | 9857 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
2013-11-28 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2013-03-10 | Deleted | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2012-12-21 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2012-10-29 | Added | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2011-07-31 | Added | RELATION | part of GO:0002040 (sprouting angiogenesis) |
2011-07-31 | Added | RELATION | is a GO:0097101 (blood vessel endothelial cell fate specification) |
2011-07-31 | Added | TERM | endothelial tip cell fate specification |
2011-07-31 | Added | DEFINITION | The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels. |
2011-07-31 | Added | SYNONYM | angiogenic tip cell fate specification |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-07-31 | Added | TERM | endothelial tip cell fate specification |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-07-31 | Added | DEFINITION | The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels. |
2011-07-31 | Added | SYNONYM | angiogenic tip cell fate specification |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-11-28 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2013-03-10 | Deleted | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2012-12-21 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2012-10-29 | Added | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2011-07-31 | Added | RELATION | part of GO:0002040 (sprouting angiogenesis) |
2011-07-31 | Added | RELATION | is a GO:0097101 (blood vessel endothelial cell fate specification) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
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